Participation of phospholipase D and α/β-protein kinase C in growth factor-induced signalling in C3H10T1/2 fibroblasts

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1632, Issue 1-3, 2003, Pages 62-71

  Thorsen, Vidar A T ^a,c   Vorland, Marta ^a   Bjørndal, Bodil ^a   Bruland, Ove ^a,b   Holmsen, Holm ^a   Lillehaug, Johan R ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^c RF Rogaland Research   (Norway)

Author keywords

C fos; C3H 10T1 2 fibroblasts; ERK1; PDGF BB; Phospholipase D; PKC; RACK1

Indexed keywords

BUTANOL; EPIDERMAL GROWTH FACTOR; MESSENGER RNA; METHIONYLGLYCYLTYROSYLPROLYLTYROSYLASPARAGINYLVALYLPROLYLASPARAGINYLTYROSYL ALANYLGLYCYLSERYLLEUCYLGLUTAMINYLGLYCYLLYSYLGLUTAMINYLLYSYLTHREONYLLYSYLTHREONYL ISOLEUCYLLYSYLGLYCYLPROPYLPROLINE; MITOGEN ACTIVATED PROTEIN KINASE 1; PEPTIDE DERIVATIVE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDIC ACID; PHOSPHOLIPASE D; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN C FOS; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL TYPE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; GENE ACTIVATION; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING;

SUIDAE;

EID: 0037680221     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1388-1981(03)00063-5     Document Type: Article

References (53)

1. Vassbotn F.S., Skar R., Holmsen H., Lillehaug J.R. Absence of PDGF-induced, PKC-independent c-fos expression in a chemically transformed C3H/10T1/2 cell clone. Exp. Cell Res. 202:1992;98-104.
2. Denhardt D.T. Signal-transducing protein phosphorylation cascade mediated by Ras/Rho proteins in mammalian cell: the potential for multiplex signalling. Biochem. J. 318:1996;729-747.
3. Kikkawa U., Takai Y., Tanaka Y., Miyake R., Nishizuka Y. Protein kinase C as a possible receptor of tumor-promoting phorbol esters. J. Biol. Chem. 258:1983;11442-11445.
4. Malarkey K., Belham C.M., Paul A., Graham A., McLees A., Scott P.H., Plevin R. The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors. Biochem. J. 309:1995;361-375.
5. Mochly-Rosen D. Localization of protein kinases by anchoring proteins: a theme in signal transduction. Science. 268:1995;247-251.
6. Disatnik M.H., Buraggi G., Mochly-Rosen D. Localization of protein kinase C isozymes in cardiac myocytes. Exp. Cell Res. 210:1994;287-297.
7. Zhou L.Y., Disatnik M., Herron G.S., Mochly-Rosen D., Karasek M.A. Differential activation of protein kinase C isozymes by phorbol ester and collagen in human skin microvascular endothelial cells. J. Invest. Dermatol. 107:1996;248-252.
8. Mochly-Rosen D., Smith B.L., Chen C.H., Disatnik M.H., Ron D. Interaction of protein kinase C with RACK1, a receptor for activated C-kinase: a role in beta protein kinase C mediated signal transduction. Biochem. Soc. Trans. 23:1995;596-600.
9. Stebbins E.G., Mochly-Rosen D. Binding specificity for RACK1 resides in the V5 region of beta II protein kinase C. J. Biol. Chem. 276:2001;29644-29650.
10. Ron D., Luo J., Mochly-Rosen D. C2 region-derived peptides inhibit translocation and function of beta protein kinase C in vivo. J. Biol. Chem. 270:1995;24180-24187.
11. Yedovitzky M., Mochly-Rosen D., Johnson J.A., Gray M.O., Ron D., Abramovitch E., Cerasi E., Nesher R. Translocation inhibitors define specificity of protein kinase C isoenzymes in pancreatic beta-cells. J. Biol. Chem. 272:1997;1417-1420.
12. Zhang Z.H., Johnson J.A., Chen L., El S.N., Mochly-Rosen D., Boutjdir M. C2 region-derived peptides of beta-protein kinase C regulate cardiac Ca2+ channels. Circ. Res. 80:1997;720-729.
13. Liliental J., Chang D.D. Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit. J. Biol. Chem. 273:1998;2379-2383.
14. Chang B.Y., Conroy K.B., Machleder E.M., Cartwright C.A. RACK1, a receptor for activated C kinase and a homolog of the β subunit of G proteins, inhibits activity of src tyrosin kinase and growth of NIH 3T3 cells. Mol. Cell. Biol. 18:1998;3245-3256.
15. Kiely P.A., Sant A., O'Connor R. RACK is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death. J. Biol. Chem. 277:2002;22581-22589.
16. Yarwood S.J., Steel M.R., Scotland G., Houslay M.D., Bolger G.B. The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform. J. Biol. Chem. 274:1999;14909-14917.
17. Exton J.H. Phospholipase D: enzymology, mechanisms of regulation, and function. Physiol. Rev. 77:1997;303-320.
18. Exton J.H. Phospholipase D. Biochim. Biophys. Acta. 1436:1998;105-115.
19. Hess J.A., Ji Q.S., Carpenter G., Exton J.H. Analysis of platelet-derived growth factor-induced phospholipase D activation in mouse embryo fibroblasts lacking phospholipase C-gamma1. J. Biol. Chem. 273:1998;20517-20524.
20. Eldar H., Benav P., Schmidt U.S., Livneh E., Liscovitch M. Up-regulation of phospholipase-D activity induced by overexpression of protein kinase C-alpha - studies in intact Swiss/3T3 cells and in detergent-solubilized membranes in vitro. J. Biol. Chem. 268:1993;12560-12564.
21. Yeo E.J., Exton J.H. Stimulation of phospholipase D by epidermal growth factor requires protein kinase C activation in Swiss 3T3 cells. J. Biol. Chem. 270:1995;3980-3988.
22. Plevin R., Cook S.J., Palmer S., Wakelam M.J.O. Multiple sources of sn-1,2-diacylglycerol in platelet-derived- growth-factor-stimulated Swiss 3T3 fibroblasts. Evidence for activation of phosphoinositidase C and phosphatidylcholine-specific phospholipase D. Biochem. J. 279:1991;559-565.
23. Ben Av P., Eli Y., Schmidt U.S., Tobias K.E., Liscovitch M. Distinct mechanisms of phospholipase D activation and attenuation utilized by different mitogens in NIH-3T3 fibroblasts. Eur. J. Biochem. 215:1993;455-463.
24. Ha K.S., Exton J.H. Differential translocation of protein kinase-C isozymes by thrombin and platelet-derived growth factor - a possible function for phosphatidylcholine-derived diacylglycerol. J. Biol. Chem. 268:1993;10534-10539.
25. Wright T.M., Shin H.S., Raben D.M. Sustained increase in 1,2-diacylglycerol precedes DNA synthesis in epidermal-growth-factor-stimulated fibroblasts. Evidence for stimulated phosphatidylcholine hydrolysis. Biochem. J. 267:1990;501-507.
26. Tsai M.H., Yu C.L., Wei F.S., Stacey D.W. The effect of GTPase activating protein upon ras is inhibited by mitogenically responsive lipids. Science. 243:1989;522-526.
27. Limatola C., Schaap D., Moolenaar W.H., van B.W. Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids. Biochem. J. 304:1994;1001-1008.
28. Jenkins G.H., Fisette P.L., Anderson R.A. Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid. J. Biol. Chem. 269:1994;11547-11554.
29. Ghosh S., Strum J.C., Sciorra V.A., Daniel L., Bell R.M. Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells. J. Biol. Chem. 271:1996;8472-8480.
30. Ghosh S., Bell R.M. Regulation of Raf-1 kinase by interaction with the lipid second messenger, phosphatidic acid. Biochem. Soc. Trans. 1997;561-565.
31. Thorsen A.T., Bjørndal B., Nolan G., Bruland O., Fukami M.H., Lillehaug J.R., Holmsen H. Expression of a peptide binding to receptor for activated C-kinase (RACK1) inhibits PMA-stimulated phospholipase D activity in C3H10T1/2 cells: dissociation of phospholipase D-mediated phosphatidylcholine breakdown from its synthesis. Biochim. Biophys. Acta. 1486:2000;163-176.
32. Rizzo M.A., Shome K., Vasudevan C., Stolz D.B., Sung T.C., Frohman M.A., Watkins S.C., Romero G. Phospholipase D and its product, phosphatidic acid, mediate agonist-dependent Raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway. J. Biol. Chem. 274:1999;1131-1139.
33. Holmsen H., Male R., Rongved S., Langeland N., Lillehaug J.R. Platelet-derived-growth-factor-stimulated heterogeneous polyphosphoinositide metabolism and uptake in C3H fibroblasts. Biochem. J. 260:1989;589-592.
34. Male R., Bjerkvig R., Lillehaug J.R. Biological and biochemical characterization of cell lines derived from initiation-promotion transformed C3H/10T1/2 cells. Carcinogenesis. 8:1987;1375-1383.
35. Feinberg A.P., Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:1983;6-13.
36. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
37. Aasland R., Akslen L.A., Varhaug J.E., Lillehaug J.R. Co-expression of the genes encoding transforming growth factor-alpha and its receptor in papillary carcinomas of the thyroid. Int. J. Cancer. 46:1990;382-387.
38. Ness G.O., Haugen D.R., Varhaug J.E., Akslen L.A., Lillehaug J.R. Cytoplasmic localization of EGF receptor in papillary thyroid carcinomas: association with the 150-kDa receptor form. Int. J. Cancer. 65:1996;161-167.
39. Thorsen V.A.T., Bruland O., Lillehaug J., Holmsen H. Choline derived from the phosphatidylcholine specific phospholipase D is not directly available for the CDP choline pathway in phorbol ester-treated C3H10T1/2 Cl 8 fibroblasts. Mol. Cell. Biochem. 187:1998;147-154.
40. Pachter J.A., Pai J.-K., Mayer-Erzell R., Petrin J.M., Dobek E., Bishop W.R. Differential regulation of phosphoinositide and phosphatidylcholine hydrolysis by protein kinase C-β1 overexpression. J. Biol. Chem. 267:1992;9826-9830.
41. Gomez C.J., Keire P. Phospholipase D: a novel major player in signal transduction. Cell. Signal. 10:1998;387-397.
42. Jiang H., Luo J.Q., Urano T., Frankel P., Lu Z., Foster D.A., Felg L.A. Involvement of Ral GTPase in v-Src-induced phospholipase D activation. Nature. 378:1995;409-412.
43. Soh J.-W., Lee E.H., Prywes R., Weinstein I.B. Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element. Mol. Cell. Biol. 19:1999;1313-1324.
44. Feig L.A., Urano T., Cantor S. Evidence for a Ras/Ral signaling cascade. Trends. Biochem. Sci. 21:1996;438-441.
45. 2 in Swiss 3T3 fibroblasts. J. Biol. Chem. 273:1998;29986-29994.
46. Min D.S., Exton J.H. Phospholipase D is associated in a phorbol ester-dependent manner with protein kinase C-alpha and with a 220-kDa protein which is phosphorylated on serine and threonine. Biochem. Biophys. Res. Commun. 248:1998;533-537.
47. Inui H., Kitami Y., Tani M., Kondo T., Inagami T. Differences in signal transduction between platelet-derived growth factor (PDGF) alpha and beta receptors in vascular smooth muscle cells. PDGF-BB is a potent mitogen, but PDGF-AA promotes only protein synthesis without activation of DNA synthesis. J. Biol. Chem. 269:1994;30546-30552.
48. Adachi T., Nakashima S., Saji S., Nakamura T., Nozawa Y. Phospholipase D activation in hepatocyte growth factor-stimulated rat hepatocytes mediates the expressions of c-jun and c-fos: involvement of protein tyrosine kinase, protein kinase C, and Ca2+. Hepatology. 24:1996;1274-1281.
49. Siddiqui R.A., Yang Y.C. Interleukin-11 induces phosphatidic acid formation and activates map kinase in mouse 3T3-L1 cells. Cell. Signal. 7:1995;247-259.
50. White M.A., Nicolette C., Minden A., Polverino A., Van A.L., Karin M., Wigler M.H. Multiple Ras functions can contribute to mammalian cell transformation. Cell. 80:1995;533-541.
51. Moodie S.A., Willumsen B.M., Weber M.J., Wolfman A. Complexes of Ras. GTP with Raf-1 and mitogen-activated protein kinase kinase [see comments]. Science. 260:1993;1658-1661.
52. Warne P.H., Viciana P.R., Downward J. Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro. Nature. 364:1993;352-355.
53. Stokoe D., Macdonald S.G., Cadwallader K., Symons M., Hancock J.F. Activation of Raf as a result of recruitment to the plasma membrane. Science. 264:1994;1463-1467.