Retroviral Transfer of T-Cell Receptor Genes into Human Peripheral Blood Lymphocytes

Methods in Molecular Biology

Volumn 215, Issue , 2003, Pages 227-234

  Clay, Timothy M ^a   Nishimura, Michael I ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Allogeneic Peripheral Blood Mononuclear Cell; Cytokine Release Assay; Immune Assay; Limit Dilution Cloning; Peripheral Blood Lymphocyte

Indexed keywords

CHROMIUM; LYMPHOCYTE ANTIGEN RECEPTOR;

ARTICLE; BIOASSAY; GENE TRANSFER; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; HUMAN; LYMPHOCYTE; METABOLISM; METHODOLOGY; RETROVIRUS;

BIOLOGICAL ASSAY; CHROMIUM ISOTOPES; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; LYMPHOCYTES; RECEPTORS, ANTIGEN, T-CELL; RETROVIRIDAE; TRANSDUCTION, GENETIC;

EID: 0037672910     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1385/1-59259-345-3:227     Document Type: Chapter

References (10)

1. Kawakami, Y., Eliyahu, S., Delgado, C. H., Robbins, P. F., Rivoltini, L., Topalian, S. L., et al. (1994) Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc. Natl. Acad. Sci. USA 91, 3515–3519.
2. Marincola, F. M., Hijazi, Y. M., Fetsch, P., Salgaller, M. L., Rivoltini, L., Cormier, J., et al. (1996) Analysis of expression of the melanoma-associated antigens MART-1 and gp100 in metastatic melanoma cell lines and in situ lesions. J. Immunother. 19, 192–205.
3. Shilyansky, J, Nishimura, M. I., Yannelli, J. R., Kawakami, Y., Jacknin, L. S., Charmley, P., et al. (1994) T-Cell receptor usage by melanoma-specific clonal and highly oligoclonal tumor-infiltrating lymphocyte lines. Proc. Natl. Acad. Sci. USA 91, 2829–2833.
4. Cole, D. J., Weil, D. P., Shilyansky, J., Custer, M., Kawakami, Y., Rosenberg, S. A., et al. (1995) Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen. Cancer Res. 55, 748–752.
5. Clay, T. M., Custer, M. C., Sachs, J., Hwu, P., Rosenberg, S. A., and Nishimura, M. I. (1999) Efficient transfer of tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity. J. Immunol. 163, 507–513.
6. Bunnell, B. A., Muul, L. M., Donahue, R. E., Blaese, R. M., and Morgan, R. A. (1995) High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes. Proc. Natl. Acad. Sci. USA 92, 7739–7743.
7. Walter, E. A., Greenberg, P. D., Gilbert, M. J., Finch, R. J., Watanabe, K. S., Thomas, E. D., et al. (1995) Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N. Engl. J. Med. 333, 1038–1044.
8. Mosca, P. J., Hobeika, A. C., Clay, T. M., Morse, M. A., and Lyerly, H. K. (2001) Direct detection of cellular immune responses to cancer vaccines. Surgery 129, 248–254.
9. Morse, M. A., Clay, T. M., Hobeika, A. C., Mosca, P. J., and Lyerly, H. K. (2001) Monitoring cellular immune responses to cancer immunotherapy. Curr. Opin. Mol. Ther. 3, 45–52.
10. Clay, T. M., Hobeika, A. C., Mosca, P. J., Lyerly, H. K., and Morse, M. A. (2001) Assays for monitoring cellular immune responses to active immunotherapy of cancer. Clinical Cancer Res. 7, 1127–1135.