Indomethacin versus meloxicam for prevention of heterotopic ossification after total hip arthroplasty

Archives of Orthopaedic and Trauma Surgery

Volumn 123, Issue 2-3, 2003, Pages 91-94

  Legenstein, Robert ^a   Bösch, Peter ^a   Ungersböck, Alfred ^a  

^a Hospital Wiener Neustadt   (Austria)

Author keywords

Cox 2; Heterotopic ossification; Non steroidal anti inflammatory drug; Prophylaxis; Total hip replacement

Indexed keywords

BONE CEMENT; INDOMETACIN; MELOXICAM; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; AGED; ARTICLE; AUSTRIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG CONTRAINDICATION; DRUG EFFICACY; FEMALE; GASTROINTESTINAL HEMORRHAGE; GASTROINTESTINAL SYMPTOM; HEADACHE; HETEROTOPIC OSSIFICATION; HIP OSTEOARTHRITIS; HUMAN; MAJOR CLINICAL STUDY; MALE; NAUSEA; PATIENT SELECTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; STATISTICAL SIGNIFICANCE; STOMACH PAIN; SURGICAL TECHNIQUE; TOTAL HIP PROSTHESIS; VERTIGO;

EID: 0037662881     PISSN: 09368051     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00402-003-0487-y     Document Type: Article

References (35)

1. Arcq M (1973) Die paraartikulären Ossifikationen - eine Komplikation der Totalendoprothese des Hüftgelenkes. Arch Orthop 77:108-131
2. Barner A (1996) Review of clinical trials and benefit/risk ratio of meloxicam. Scand J Rheumatol 25 [Suppl 102]:29-37
3. Bengt IE et al (1991) Prevention of deep vein thrombosis and pulmonary embolism after total hip replacement. J Bone Joint Surg Am 73:484-493
4. Braun K (1999) Präopertive Radiatio zur Prophylaxe heterotoper Ossifikationen nach endoprothetischem Hüftgelenkersatz. Z Orthop 137:22-23
5. Bremen-Kühne R v et al (1997) Indomethacin - Kurzzeittherapie vs Einzeitige low-dose-radiatio zur Prophylaxe perirtkulärer Ossifikationen (PAO) nach HTEP. Z Orthop 135:422-429
6. Brooker AF et al (1973) Ectopic ossification following total hip replacement. J Bone Joint Surg Am 55:1629-1632
7. Brückl R, Frey M (1997) Prophylaxe paraartikulärer Ossifikation durch Strablentherapie nach zementloser Hüft-TEP-Implantation. Z Orthop 135:430-433
8. DeLee J, Ferrari A, Charnley J (1976) Ectopic bone formation following low friction arthroplasty of the hip. Clin Orthop 121: 53-59
9. Dequecker J et al (1998) Improvement in gastrointestinal tolerability the selective cyclooxigenase (COX)-2 inhibitor, meloxicam, compared with piroxicam: results of the safety and efficacy large-scale evaluation of COX-inhibiting therapies (SELECT) trial in osteoarthritis. Br J Rheumatol 37:946-951
10. Dorn U et al (1998) Indomethacin for prevention of heterotopic ossification after hip arthroplasty. Acta Orthop Scand 69:107-110
11. Drees P (1999) Das Risiko periartikulärer Ossifikationen beim Hüftgelenkersatz. Z Orthop 137:16-17
12. Emery P (1996) Clinical implications of selective cyclooxygenase-2 inhibition. Scand J Rheumatol 25 [Suppl 102]:23-28
13. Fröhling MA (1998) Periartikuläre heterotope Ossifikationen nach Hüft-TEP - Ein Impingement des Hüftgelenkes. Z Orthop 136:A54
14. Gebuhr P et al (1997) Naproxen given to prevent heterotopic ossification does not increase prosthetic loosening. Orthopaedics 5:21-23
15. Gierse H et al (1997) Zur Prophylaxe von periartikulären Vernöcherungen - mit Ergebnissen einer randomisierten, doppel-blinden Studie zum Vergleich von Acemetacin versus Indometacin. Z Orthop 135:417-421
16. Goldmann AR et al (1993) Strahlentherapie zur Prophylaxe von periartkulären, heterotopen Ossifikationen nach Implantation von HTEP. Z Orthop 131:151-155
17. Hawkey C et al (1998) Gastrointestinal tolerability of the COX-2 inhibitor, meloxicam, in osteoarthritis patients: the meloxicam large scale international study safety asesment (MELISSA). Br J Rhreumatol 37:937-945
18. Heyd R et al (1995) Die postoperative, konventionelle fraktionierte Strahlentherapie zur Prävention heterotoper Ossifikationen nach TEP des Hüftgelenks. Röntgenpraxis 48:233-237
19. Jockheck M et al (1998) Prevention of periarticular heterotopic ossification after endoprosthetic hip joint replacement by means of diclofenac. Arch Orthop Trauma Surg 117:337-340
20. Kienapfel H et al (1999) Prevention of heterotopic bone formation after total hip arthroplasty: a prospective randomised study comparing postoperative radiation therapy with indomethacin medication. Arch Orthop Trauma Surg 119:296-302
21. Knelles D et al (1997) Prevention of heterotopic ossification after total hip replacement. J Bone Joint Surg Br 79:596-602
22. Koorevaar CT et al (1999) No effective prophylaxis of heterotopic ossification with short-term ibuprofen. Arch Orthop Trauma Surg 119:183-185
23. Lockie LM (1986) Tolerability and efficacy of long-term daily administration of indomethacin for moderate to severe chronic arthritic disorders. Clin Ther 8:398-405
24. Moore K D et al (1998) Indomethacin versus radiation therapy for prophylaxis against heterotopic ossification in acetabular fractures. J Bone Joint Surg Br 80:259-263
25. Nilsson OS (1998) Heterotopic ossification - editorial. Acta Orthop, Scand 69:103-106
26. Noble S, Balfour JA (1996) Meloxicam. Drugs 51:424-432
27. Patrignani P et al (1997) Differential inhibition of human protaglandin endoperoxide synthase-1 and -2 by nonsteroidal antiinflammatory drugs. J Physiol Pharmacol 48:623-631
28. Peterson P-E et al (1998) Preventive effects of ibuprofen on periarticular heterotopic ossification after total hip arthroplasty. Acta Orthop Scand 69:111-115
29. Quack G et al (1998) Prä- versus postoperative Radiatio zur Prophylaxe von postoperativen Ossifikationen nach TEP. Z Orthop 136
30. Ritter MA, Sieber JM (1985) Prophylactic indomethacin for prevention of heterotopic bone formation following total hip arthroplasty. Clin Orthop 196:217-225
31. Schmidt SA et al (1988) The use of indomethacin to prevent the formation of heterotopic bone after total hip replacement. J Bone Joint Surg Am 70:834-838
32. Sell S, Schleh T (1999) C-reactive protein as an early indicator of the formation of heterotopic ossifications after total hip replacement. Arch Orthop Trauma Surg 119:205-207
33. Van Leeuwen WM et al (1998) Preoperative irradiation for prophylaxis of ectopic ossification after hip arthroplasty. Acta Orthop Scand 69:116-118
34. Vane JR, Botting RM (1996) Mechanism of action of antiinflammatory drugs. Scand J Rheumatol 25 [Suppl 102]:9-21
35. Trnka H-J et al (1999) Stable bony integration with and without short term indomethacin prophylaxis. Arch Orthop Trauma Surg 119:456-460