메뉴 건너뛰기




Volumn 26, Issue 4, 2003, Pages 307-313

Bezafibrate improves hypertension and insulin sensitivity in humans

Author keywords

Bezafibrate; Fatty acid; Glucose tolerance; Insulin; Triglyceride

Indexed keywords

ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; BEZAFIBRATE; GLUCOSE; MEMBRANE LIPID; PLACEBO; SATURATED FATTY ACID;

EID: 0037649053     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.26.307     Document Type: Article
Times cited : (38)

References (42)
  • 1
    • 85008093701 scopus 로고
    • Hyperinsulinemia, insulin resistance, and blood pressure
    • Ferrannini E, Galvan AQ: Hyperinsulinemia, insulin resistance, and blood pressure. Hypertens Res 1992; 15: 67-75.
    • (1992) Hypertens. Res. , vol.15 , pp. 67-75
    • Ferrannini, E.1    Galvan, A.Q.2
  • 2
    • 7044263151 scopus 로고    scopus 로고
    • Insulin resistance seen in non-insulin dependent diabetes mellitus and hypertension
    • Kawamori R: Insulin resistance seen in non-insulin dependent diabetes mellitus and hypertension. Hypertens Res 1996; 19 (Suppl 1): S61-S64.
    • (1996) Hypertens. Res. , vol.19 , Issue.SUPPL. 1
    • Kawamori, R.1
  • 3
    • 0026021161 scopus 로고
    • Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
    • DeFronzo R, Ferrannini E: Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 1991; 14: 173-194.
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • DeFronzo, R.1    Ferrannini, E.2
  • 4
    • 0023117178 scopus 로고
    • Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity
    • Fujioka S, Matsuzawa Y, Tokunaga K, et al: Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity. Metabolism 1987; 36: 54-59.
    • (1987) Metabolism , vol.36 , pp. 54-59
    • Fujioka, S.1    Matsuzawa, Y.2    Tokunaga, K.3
  • 5
    • 0032768291 scopus 로고    scopus 로고
    • Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: Usefulness of leptin for the treatment of obesity-associated diabetes
    • Masuzaki H, Ogawa Y, Aizawa-Abe M, et al: Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: usefulness of leptin for the treatment of obesity-associated diabetes. Diabetes 1999; 48: 1615-1622.
    • (1999) Diabetes , vol.48 , pp. 1615-1622
    • Masuzaki, H.1    Ogawa, Y.2    Aizawa-Abe, M.3
  • 6
    • 0032779351 scopus 로고    scopus 로고
    • Molecular mechanism of metabolic syndrome X: Contribution of adipocytokines adipocyte-derived bioactive substances
    • Matsuzawa Y, Funahashi T, Nakamura T: Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocyte-derived bioactive substances. Ann N Y Acad Sci 1999; 892: 146-154.
    • (1999) Ann. N Y Acad. Sci. , vol.892 , pp. 146-154
    • Matsuzawa, Y.1    Funahashi, T.2    Nakamura, T.3
  • 7
    • 0036094913 scopus 로고    scopus 로고
    • Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis
    • Barbier O, Torra IP, Duguay Y, et al: Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis. Arterioscler Thromb Vasc Biol 2002; 22: 717-726.
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , pp. 717-726
    • Barbier, O.1    Torra, I.P.2    Duguay, Y.3
  • 9
    • 0027395358 scopus 로고
    • The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids
    • Borkman M, Storlien LH, Pan DA, et al: The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. N Engl J Med 1993; 328: 238-244.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 238-244
    • Borkman, M.1    Storlien, L.H.2    Pan, D.A.3
  • 10
    • 0029948212 scopus 로고    scopus 로고
    • Mechanism of free fatty acid-induced insulin resistance in humans
    • Roden M, Price TB, Perseghin G, et al: Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest 1996; 97: 2859-2865.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2859-2865
    • Roden, M.1    Price, T.B.2    Perseghin, G.3
  • 12
    • 0023926655 scopus 로고
    • Improvement of glucose tolerance in NIDDM by clofibrate: Randomized double-blind study
    • Kobayashi M, Shigeta Y, Hirata Y, et al: Improvement of glucose tolerance in NIDDM by clofibrate: randomized double-blind study. Diabetes Care 1988; 11: 195-199.
    • (1988) Diabetes Care , vol.11 , pp. 195-199
    • Kobayashi, M.1    Shigeta, Y.2    Hirata, Y.3
  • 13
    • 0025151893 scopus 로고
    • Lowering of plasma glucose concentrations with bezatibrate in patients with moderately control NIDDM
    • Jones IR, Swai A, Taylor R, Miller M, Laker MF, Alberti KGMM: Lowering of plasma glucose concentrations with bezatibrate in patients with moderately control NIDDM. Diabetes Care 1990; 13: 855-863.
    • (1990) Diabetes Care , vol.13 , pp. 855-863
    • Jones, I.R.1    Swai, A.2    Taylor, R.3    Miller, M.4    Laker, M.F.5    Alberti, K.G.M.M.6
  • 14
    • 0026066026 scopus 로고
    • Bezafibrate retard in type II diabetes patients: Effects of hemostasis and glucose homeostasis
    • Mikhailidis DP, Mathur S, Barradas MA, Dandoma P: Bezafibrate retard in type II diabetes patients: effects of hemostasis and glucose homeostasis. J Cardiovasc Pharmacol 1990; 16 (Suppl 9): 26-29.
    • (1990) J. Cardiovasc. Pharmacol. , vol.16 , Issue.SUPPL. 9 , pp. 26-29
    • Mikhailidis, D.P.1    Mathur, S.2    Barradas, M.A.3    Dandoma, P.4
  • 15
    • 0028090641 scopus 로고
    • Improvement of glucose tolerance by bezafibrate in obese patients with hyperlipidemia and impaired glucose tolerance
    • Inoue I, Takahashi K, Katayama S, et al: Improvement of glucose tolerance by bezafibrate in obese patients with hyperlipidemia and impaired glucose tolerance. Diabetes Res Clin Pract 1994; 25: 199-205.
    • (1994) Diabetes Res. Clin. Pract. , vol.25 , pp. 199-205
    • Inoue, I.1    Takahashi, K.2    Katayama, S.3
  • 16
    • 0034064204 scopus 로고    scopus 로고
    • Bezafibrate reduces blood glucose in type 2 diabetes mellitus
    • Ogawa S, Takeuchi K, Sugimura K, et al: Bezafibrate reduces blood glucose in type 2 diabetes mellitus. Metabolism 2000; 49: 331-334.
    • (2000) Metabolism , vol.49 , pp. 331-334
    • Ogawa, S.1    Takeuchi, K.2    Sugimura, K.3
  • 17
    • 0036686288 scopus 로고    scopus 로고
    • Fenofibrate improves insulin sensitivity in connection with intramuscular lipid content, muscle fatty acid-binding protein, and β-oxidation in skeletal muscle
    • Furuhashi M, Ura N, Murakami H, et al: Fenofibrate improves insulin sensitivity in connection with intramuscular lipid content, muscle fatty acid-binding protein, and β-oxidation in skeletal muscle. J Endocrinol 2002; 174: 321-329.
    • (2002) J. Endocrinol. , vol.174 , pp. 321-329
    • Furuhashi, M.1    Ura, N.2    Murakami, H.3
  • 18
    • 0015348189 scopus 로고
    • Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge
    • Friedewald WT, Levy RT, Fredrickson DS: Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin Chem 1972; 18: 499-502.
    • (1972) Clin. Chem. , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.T.2    Fredrickson, D.S.3
  • 19
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 20
    • 1842334456 scopus 로고    scopus 로고
    • The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
    • The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997; 20: 1183-1197.
    • (1997) Diabetes Care , vol.20 , pp. 1183-1197
  • 21
    • 0025066328 scopus 로고
    • Insulin release and peripheral sensitivity at the oral glucose tolerance test
    • Cederholm J, Wibell L: Insulin release and peripheral sensitivity at the oral glucose tolerance test. Diabetes Res Clin Pract 1990; 10: 167-175.
    • (1990) Diabetes Res. Clin. Pract. , vol.10 , pp. 167-175
    • Cederholm, J.1    Wibell, L.2
  • 22
    • 0016355004 scopus 로고
    • The preparation of red cell ghosts (membranes)
    • Fleisher S, Packer L (eds): New York, Academic Press
    • Hanahan DJ, Ekholm JE: The preparation of red cell ghosts (membranes), in Fleisher S, Packer L (eds): Methods in Enzymology, Vol 31. New York, Academic Press, 1974, pp 168-172.
    • (1974) Methods in Enzymology , vol.31 , pp. 168-172
    • Hanahan, D.J.1    Ekholm, J.E.2
  • 23
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ: A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959; 37: 911-917.
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 24
    • 0015512201 scopus 로고
    • Haemolysis and changes in erythrocyte membranes
    • Shohet SB: Haemolysis and changes in erythrocyte membranes. New Engl J Med 1972; 286: 577-579.
    • (1972) New Engl. J. Med. , vol.286 , pp. 577-579
    • Shohet, S.B.1
  • 25
    • 0017058767 scopus 로고
    • The exchange of phospholipids between rat erythrocytes and plasma, and the translocation of phosphatidylcholine across the red cell membrane, are temperature-dependent processes
    • Renooij W, Van Golde LMG: The exchange of phospholipids between rat erythrocytes and plasma, and the translocation of phosphatidylcholine across the red cell membrane, are temperature-dependent processes. FEBS Lett 1976; 71: 321-324.
    • (1976) FEBS Lett. , vol.71 , pp. 321-324
    • Renooij, W.1    Van Golde, L.M.G.2
  • 26
    • 0022538893 scopus 로고
    • Dietary sardine oil increases erythrocyte membrane fluidity in diabetic patients
    • Kamada T, Yamashita T, Baba Y, et al: Dietary sardine oil increases erythrocyte membrane fluidity in diabetic patients. Diabetes 1986; 35: 604-611.
    • (1986) Diabetes , vol.35 , pp. 604-611
    • Kamada, T.1    Yamashita, T.2    Baba, Y.3
  • 27
    • 0021341436 scopus 로고
    • The modification of mammalian membrane polyunsaturated fatty acid composition in relation to membrane fluidity and function
    • Stubbs CD, Smith AD: The modification of mammalian membrane polyunsaturated fatty acid composition in relation to membrane fluidity and function. Biochim Biophys Acta 1984; 779: 89-137.
    • (1984) Biochim. Biophys. Acta , vol.779 , pp. 89-137
    • Stubbs, C.D.1    Smith, A.D.2
  • 28
    • 0031051533 scopus 로고    scopus 로고
    • Improved insulin sensitivity by bezafibrate in rats: Relationship to fatty acid composition of skeletal-muscle triglycerides
    • Matsui H, Okumura K, Kawakami K, Hibino M, Toki Y, Ito T: Improved insulin sensitivity by bezafibrate in rats: relationship to fatty acid composition of skeletal-muscle triglycerides. Diabetes 1997; 46: 348-353.
    • (1997) Diabetes , vol.46 , pp. 348-353
    • Matsui, H.1    Okumura, K.2    Kawakami, K.3    Hibino, M.4    Toki, Y.5    Ito, T.6
  • 29
    • 0035002843 scopus 로고    scopus 로고
    • Hyperinsulinemia is a determinant of membrane fluidity of erythrocytes in essential hypertension
    • Tsuda K, Kinoshita Y, Nishio I, Masuyama Y: Hyperinsulinemia is a determinant of membrane fluidity of erythrocytes in essential hypertension. Am J Hypertens 2001; 14: 419-423.
    • (2001) Am. J. Hypertens. , vol.14 , pp. 419-423
    • Tsuda, K.1    Kinoshita, Y.2    Nishio, I.3    Masuyama, Y.4
  • 30
    • 0021984608 scopus 로고
    • Gammalinoleic acid attenuates cardiovascular responses to stress in borderline hypertensive rats
    • Mills DE, Summers MR, Ward RP: Gammalinoleic acid attenuates cardiovascular responses to stress in borderline hypertensive rats. Lipids 1985; 20: 573-577.
    • (1985) Lipids , vol.20 , pp. 573-577
    • Mills, D.E.1    Summers, M.R.2    Ward, R.P.3
  • 31
    • 0037272851 scopus 로고    scopus 로고
    • + exchanger in fructose-fed borderline hypertensive rats
    • + exchanger in fructose-fed borderline hypertensive rats. Hypertens Res 2003; 26: 111-116.
    • (2003) Hypertens. Res. , vol.26 , pp. 111-116
    • Fujioka, Y.1    Masai, M.2    Tsuboi, S.3
  • 32
    • 0025308724 scopus 로고
    • Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension
    • Bønaa KH, Bjerve KS, Straume B, Gram IT, Thelle D: Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension. N Engl J Med 1990; 322: 195-201.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 195-201
    • Bønaa, K.H.1    Bjerve, K.S.2    Straume, B.3    Gram, I.T.4    Thelle, D.5
  • 33
    • 0024582271 scopus 로고
    • The antihypertensive effects of fish oil
    • Knapp HR, FitzGerald GA: The antihypertensive effects of fish oil. N Engl J Med 1989; 320: 1037-1043.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 1037-1043
    • Knapp, H.R.1    FitzGerald, G.A.2
  • 34
    • 0035158036 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid on blood pressure, cell membrane fatty acids, and intracellular sodium concentration in essential hypertension
    • Miyajima T, Tsujino T, Saito K, Yokoyama M: Effects of eicosapentaenoic acid on blood pressure, cell membrane fatty acids, and intracellular sodium concentration in essential hypertension. Hypertens Res 2001; 24: 537-542.
    • (2001) Hypertens. Res. , vol.24 , pp. 537-542
    • Miyajima, T.1    Tsujino, T.2    Saito, K.3    Yokoyama, M.4
  • 35
    • 0033378092 scopus 로고    scopus 로고
    • Calcium-mediated mechanisms of eicosapentaenoic acid-induced relaxation in hypertensive rat aorta
    • Engler MB, Ma Y-H, Engler MM: Calcium-mediated mechanisms of eicosapentaenoic acid-induced relaxation in hypertensive rat aorta. Am J Hypertens 1999; 12: 1225-1235.
    • (1999) Am. J. Hypertens. , vol.12 , pp. 1225-1235
    • Engler, M.B.1    Ma, Y.-H.2    Engler, M.M.3
  • 36
    • 0027448328 scopus 로고
    • Dietary fish oil augments nitric oxide production or release in patients with type 2 (non-insulin-dependent) diabetes mellitus
    • McVeigh GE, Brennan GM, Johnston GD, et al: Dietary fish oil augments nitric oxide production or release in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 1993; 36: 33-38.
    • (1993) Diabetologia , vol.36 , pp. 33-38
    • McVeigh, G.E.1    Brennan, G.M.2    Johnston, G.D.3
  • 37
    • 0023213349 scopus 로고
    • Relationships between plasma lipoprotein concentrations and insulin action in an obese hyperinsulinemic population
    • Abbott WGH, Lillioja S, Young AA, et al: Relationships between plasma lipoprotein concentrations and insulin action in an obese hyperinsulinemic population. Diabetes 1987; 36: 897-904.
    • (1987) Diabetes , vol.36 , pp. 897-904
    • Abbott, W.G.H.1    Lillioja, S.2    Young, A.A.3
  • 38
    • 0024357130 scopus 로고
    • Linoleic acid supplementation, membrane lipids and leukocyte sodium transport in normotensive humans
    • Robertson DA, Haegerty AM, Ollerenshaw JD, Swales JD: Linoleic acid supplementation, membrane lipids and leukocyte sodium transport in normotensive humans. J Hum Hypertens 1989; 3: 117-123.
    • (1989) J. Hum. Hypertens. , vol.3 , pp. 117-123
    • Robertson, D.A.1    Haegerty, A.M.2    Ollerenshaw, J.D.3    Swales, J.D.4
  • 39
    • 0026754120 scopus 로고
    • Effects induced by olive oil-rich diet on erythrocytes membrane lipids and sodium-potassium transports in postmenopausal hypertensive women
    • Corrocher R, Pagnan A, Ambrosio GB, et al: Effects induced by olive oil-rich diet on erythrocytes membrane lipids and sodium-potassium transports in postmenopausal hypertensive women. J Endocrinol Invest 1992; 15: 369-376.
    • (1992) J. Endocrinol. Invest. , vol.15 , pp. 369-376
    • Corrocher, R.1    Pagnan, A.2    Ambrosio, G.B.3
  • 40
    • 0028144613 scopus 로고
    • Influence of cholesterol lowering on plasma membrane lipids and cationic transport systems
    • Lijnen P, Celis H, Fagard R, Staessen J, Amery A: Influence of cholesterol lowering on plasma membrane lipids and cationic transport systems. J Hypertens 1994; 12: 59-64.
    • (1994) J. Hypertens. , vol.12 , pp. 59-64
    • Lijnen, P.1    Celis, H.2    Fagard, R.3    Staessen, J.4    Amery, A.5
  • 41
    • 0031001513 scopus 로고    scopus 로고
    • Renal P450 metabolites of arachidonic acid and the development of hypertension in Dahl salt-sensitive rats
    • Roman RJ, Alonso-Galicia M, Wilson TW: Renal P450 metabolites of arachidonic acid and the development of hypertension in Dahl salt-sensitive rats. Am J Hypertens 1997; 10(Suppl): 63S-67S.
    • (1997) Am. J. Hypertens. , vol.10 , Issue.SUPPL.
    • Roman, R.J.1    Alonso-Galicia, M.2    Wilson, T.W.3
  • 42
    • 0028901028 scopus 로고
    • Enhancement of insulin sensitivity by troglitazone lowers blood pressure in diabetic hypertensives
    • Ogihara T, Rakugi H, Ikegami H, Mikami H, Masuo K: Enhancement of insulin sensitivity by troglitazone lowers blood pressure in diabetic hypertensives. Am J Hypertens 1995; 8: 316-320.
    • (1995) Am. J. Hypertens. , vol.8 , pp. 316-320
    • Ogihara, T.1    Rakugi, H.2    Ikegami, H.3    Mikami, H.4    Masuo, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.