The partial response of lung metastases arising from dermatofibrosarcoma protuberans after one month of imatinib mesylate therapy - A case report

Nowotwory

Volumn 53, Issue 2, 2003, Pages 165-168

  Ruka, Włodzimierz ^a   Falkowski, Sławomir ^a   Grzesiakowska, Urszula ^a   Wudarska, Justyna ^a   Nasierowska Guttmejer, Anna ^a   Nowak Dement, Anna ^a   Nowecki, Zbigniew ^a   Ptaszyński, Konrad ^a   Rutkowski, Piotr ^a  

^a INSTITUTE OF ONCOLOGY   (Poland)

Author keywords

Dermatofibrosarcoma protuberans; Imatinib; Sarcoma

Indexed keywords

IMATINIB; PLATELET DERIVED GROWTH FACTOR B; PROTEIN KINASE INHIBITOR;

ADULT; ADVANCED CANCER; ARTICLE; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER RECURRENCE; CANCER REGRESSION; CANCER SURGERY; CASE REPORT; DERMATOFIBROSARCOMA PROTUBERANS; DOSE TIME EFFECT RELATION; DRUG MECHANISM; FEMALE; HUMAN; LUNG METASTASIS; METASTASIS INHIBITION; PARTIAL REGRESSION;

EID: 0037648813     PISSN: 0029540X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Ohtani N, Fukusato T, Tzuka F. Sarcomatous dermatofibrosarcoma protuberans metastasized to the lung: preservation of CD34 expresion in tumor cells. Pathol Int 1998; 48: 989-93.
2. Grosdidier G, Sibille P, Borrelly et al. Pulmonary metastasis of a dermatofibrosarcoma. Ann Chir 1991; 45: 724-5.
3. Volpe R, Carbone A. Dermatofibrosarcoma protuberans metastatic to lymph nodes and showing a dominant histiocytic component. Am J Dermatopathol 1983; 5; 327-34.
4. Hausner RJ, Vargas-Cortes F, Alexander RW. Dermatofibrosarcoma protuberans with lymph node involvement. A case report of simultaneous occurrence with an atypical fibroxanthoma of the skin. Arch Dermatol 1978; 114; 88-91.
5. Kahn LB, Saxe N, Gordon W. Dermatofibrosarcoma protuberans with lymph node and pulmonary metastases. Arch Dermatol 1978; 114; 599-601.
6. Buchdunger E, O'Reilly T, Wood J. Pharmacology of imatinib (STI571). Eur J Canc 2002; 38: suppl. 5 28-36.
7. Sjoblom T et al. Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis. Cancer Res. 2001, 61, 5778-5783.
8. Awan RA. Patients with metastatic sarcoma arising from dermatofibrosarcoma protuberans (DFSP) may respond to imatinib (STI571, Gleevec). ASCO Conference, Orlando, 2002, abstract 1637.
9. Rubin BP et al. Molecular targeting of platelet-derived growth factor B by imatinib mesylate in a patient with metastatic dermatofibrosarcoma protuberans. JCO 2002; 20: 3586-91.
10. Kikuchi K, Soma Y, Fujimoto M et al. Dermatofibrosarcoma protuberans: increased growth response to platelet-derived factor BB in cell culture. Biochem Biophys Res Commun 1993; 196: 409-15.
11. Sheng WQ, Hashimoto H, Okamoto S et al. Expresion of COLA1-PDGFB fusion transcripts in superficial adult fibrosarcoma suggests a close relantionship to dermatofibrosarcoma protuberans. J Pathol 2001; 194: 88-94.
12. Maire G, Martin L, Michalak-Provost S et al. Fusion of COLIA1 exon 29 with PDGFB exon 2 in a der(22)t(17;22) in a pediatric giant cell fibroblastoma with a pigmented Bednar tumor component. Evidence for age-related chromosomal pattern in dermatofibrosarcoma protuberans and related tumors. Cancer Genet Cytogenet 2002; 134: 156-61.
13. Nishio J, Iwasaki H, Ishiguro M et al. Supernumerary ring chromosome in a Bednar tumor (pigmented dermatofibrosarcoma protuberans) is composed of interspersed sequence from chromosomes 17 and 22: a fluorescence in situ hybridization and comparative genomic hybridization analysis. Genes Chromosomes Cancer 2001; 30: 305-9.
14. Mentzel T, Beham A, Katenkamp D et al. Fibrosarcomatous ("high grade") dermatofibrosarcoma protuberans: clinicopathologic and immunohistochemical study of a series of 41 cases with emphasis on prognostic significance. Am J Surg Pathol 1998; 22: 576-87.
15. Ding J, Hashimoto H, Enjoji M. Dermatofibrosarcoma protuberans with fibrosarcomatous areas. A clinicopathologic study of nine cases and a comparison with allied tumors. Cancer 1989; 64: 721-29.
16. Zamecnik M. Fibrosarcomatous dermatofibrosarcoma protuberans with giant rosettes. Am J Dermathopathol 2001; 23: 41-5.
17. Goldblum JR. CD34 positivity in fibrosarcomas which arise in dermatofibrosarcoma protuberans. Arch Pathol Lab Med 1995; 119: 238-41.
18. Pedeutour F, Simon MP, Minoletti F et al. Translocation, t917;22)(q22;q13), in dermatofibrosarcoma protuberans: a new tumor-associated chromosome rearrangement. Cytogenet Cell Genet 1996; 72: 171-4.