메뉴 건너뛰기




Volumn 289, Issue 19, 2003, Pages 2575-2577

Clinical Trials - Multiple Treatments, Multiple End Points, and Multiple Lessons

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL TRIAL; EDITORIAL; EVIDENCE BASED MEDICINE; MEDICAL RESEARCH; MORTALITY; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TREATMENT OUTCOME; TREATMENT PLANNING; VALIDATION PROCESS; CONTROLLED CLINICAL TRIAL; METHODOLOGY; NOTE; RANDOMIZED CONTROLLED TRIAL; STANDARD; STATISTICS;

EID: 0037636758     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.289.19.2575     Document Type: Editorial
Times cited : (75)

References (25)
  • 1
    • 0022640774 scopus 로고
    • Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction
    • Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico (GISSI). Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet. 1986;1:397-402.
    • (1986) Lancet , vol.1 , pp. 397-402
  • 2
    • 0037872688 scopus 로고    scopus 로고
    • Composite outcomes in randomized trials: Greater precision but with greater uncertainty?
    • Freemantle N, Calvert M, Wood J, Eastaugh J, Griffin C. Composite outcomes in randomized trials: greater precision but with greater uncertainty? JAMA. 2003;289:2554-2559.
    • (2003) JAMA , vol.289 , pp. 2554-2559
    • Freemantle, N.1    Calvert, M.2    Wood, J.3    Eastaugh, J.4    Griffin, C.5
  • 3
    • 0031026945 scopus 로고    scopus 로고
    • Dead is dead - Artificial definitions are no substitute
    • Gottlieb SS. Dead is dead - artificial definitions are no substitute. Lancet. 1997;349:662-663.
    • (1997) Lancet , vol.349 , pp. 662-663
    • Gottlieb, S.S.1
  • 5
    • 0031058514 scopus 로고    scopus 로고
    • Perspectives on large-scale cardiovascular clinical trials for the new millennium
    • Topol EJ, Califf RM, Van de Werf F, et al, Virtual Coordinating Center for Global Collaborative Cardiovascular Research (VIGOUR) Group, Perspectives on large-scale cardiovascular clinical trials for the new millennium. Circulation. 1997;95:1072-1082.
    • (1997) Circulation , vol.95 , pp. 1072-1082
    • Topol, E.J.1    Califf, R.M.2    Van De Werf, F.3
  • 6
    • 0032534989 scopus 로고    scopus 로고
    • Accuracy of death certificates for coding coronary heart disease as the cause of death
    • Lloyd-Jones DM, Martin DO, Larson MG, Levy D. Accuracy of death certificates for coding coronary heart disease as the cause of death. Ann Intern Med. 1998;129:1020-1026.
    • (1998) Ann Intern Med , vol.129 , pp. 1020-1026
    • Lloyd-Jones, D.M.1    Martin, D.O.2    Larson, M.G.3    Levy, D.4
  • 7
    • 0031029373 scopus 로고    scopus 로고
    • Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT
    • Cairns JA, Connolly SJ, Roberts R, Gent M, Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Investigators. Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT. Lancet. 1997;349:675-682.
    • (1997) Lancet , vol.349 , pp. 675-682
    • Cairns, J.A.1    Connolly, S.J.2    Roberts, R.3    Gent, M.4
  • 8
    • 0008926519 scopus 로고    scopus 로고
    • Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes
    • PURSUIT Trial Investigators. Inhibition of platelet glycoprotein IIb/ IIIa with eptifibatide in patients with acute coronary syndromes. N Engl J Med. 1998;339:436-443.
    • (1998) N Engl J Med , vol.339 , pp. 436-443
  • 9
    • 0028070548 scopus 로고
    • The continuing unethical use of placebo controls
    • Rothman KJ, Michels KB. The continuing unethical use of placebo controls. N Engl J Med. 1994;331:394-398.
    • (1994) N Engl J Med , vol.331 , pp. 394-398
    • Rothman, K.J.1    Michels, K.B.2
  • 10
    • 0037453968 scopus 로고    scopus 로고
    • Bivalirudin and provisional glycoprotein Ilb/IlIa blockade compared with heparin and planned glycoprotein Ilb/ IIIa blockade during percutaneous coronary intervention: REPLACE-2 randomized trial
    • Lincoff AM, Bittl JA, Harrington RA, et al. Bivalirudin and provisional glycoprotein Ilb/IlIa blockade compared with heparin and planned glycoprotein Ilb/ IIIa blockade during percutaneous coronary intervention: REPLACE-2 randomized trial. JAMA, 2003;289:853-863,
    • (2003) JAMA , vol.289 , pp. 853-863
    • Lincoff, A.M.1    Bittl, J.A.2    Harrington, R.A.3
  • 11
    • 0026011647 scopus 로고
    • Mortality and morbidity in patients receiving encainide, flecainide, or placebo: The Cardiac Arrhythmia Suppression Trial
    • Echt DS, Liebson PR, Mitchell LB, et al. Mortality and morbidity in patients receiving encainide, flecainide, or placebo: the Cardiac Arrhythmia Suppression Trial. N Engl J Med. 1991;324:781-788.
    • (1991) N Engl J Med , vol.324 , pp. 781-788
    • Echt, D.S.1    Liebson, P.R.2    Mitchell, L.B.3
  • 12
    • 0032126372 scopus 로고    scopus 로고
    • Differences between local investigator and core laboratory interpretation of the admission electrocardiogram in patients with unstable angina pectoris or non-Q-wave myocardial infarction (a Thrombin Inhibition in Myocardial Ischemia [TRIM] substudy)
    • Holmvang L, Hasbak P, Clemmensen P, Wagner G, Grande P. Differences between local investigator and core laboratory interpretation of the admission electrocardiogram in patients with unstable angina pectoris or non-Q-wave myocardial infarction (a Thrombin Inhibition in Myocardial Ischemia [TRIM] substudy). Am J Cardiol. 1998;82:54-60.
    • (1998) Am J Cardiol , vol.82 , pp. 54-60
    • Holmvang, L.1    Hasbak, P.2    Clemmensen, P.3    Wagner, G.4    Grande, P.5
  • 13
    • 17944380212 scopus 로고    scopus 로고
    • Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: Review of the PURSUIT study
    • Mahaffey KW, Harrington RA, Akkerhuis M, et al. Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: review of the PURSUIT study. Curr Control Trials Cardiovasc Med. 2001;2:187-194.
    • (2001) Curr Control Trials Cardiovasc Med , vol.2 , pp. 187-194
    • Mahaffey, K.W.1    Harrington, R.A.2    Akkerhuis, M.3
  • 14
    • 0036480190 scopus 로고    scopus 로고
    • Misreporting of myocardial infarction end points: Results of adjudication by a central clinical events committee in the PARAGON-B trial
    • Mahaffey KW, Roe MT, Dyke CK, et al, Second Platelet IIb/IIIa Antagonist for the Reduction of Acute Coronary Syndrome Events in a Global Organization Network Trial. Misreporting of myocardial infarction end points: results of adjudication by a central clinical events committee in the PARAGON-B trial. Am Heart J. 2002;143:242-248.
    • (2002) Am Heart J , vol.143 , pp. 242-248
    • Mahaffey, K.W.1    Roe, M.T.2    Dyke, C.K.3
  • 15
    • 0033135701 scopus 로고    scopus 로고
    • The impact of an end-point committee in a large multicentre, randomized, placebo-controlled clinical trial: Results with and without the end-point committee's final decision on end-points
    • Naslund U, Grip L, Fischer-Hansen J, Gundersen T, Lehto S, Wallentin L. The impact of an end-point committee in a large multicentre, randomized, placebo-controlled clinical trial: results with and without the end-point committee's final decision on end-points. Eur Heart J. 1999;20:771-777.
    • (1999) Eur Heart J , vol.20 , pp. 771-777
    • Naslund, U.1    Grip, L.2    Fischer-Hansen, J.3    Gundersen, T.4    Lehto, S.5    Wallentin, L.6
  • 16
    • 0037420275 scopus 로고    scopus 로고
    • Outcome of elderly patients with chronic symptomatic coronary artery disease with an invasive vs optimized medical treatment strategy: One-year results of the randomized TIME trial
    • Pfisterer M, Buser P, Osswald S, et al. Outcome of elderly patients with chronic symptomatic coronary artery disease with an invasive vs optimized medical treatment strategy: one-year results of the randomized TIME trial. JAMA. 2003;289:1117-1123.
    • (2003) JAMA , vol.289 , pp. 1117-1123
    • Pfisterer, M.1    Buser, P.2    Osswald, S.3
  • 17
    • 0028154813 scopus 로고
    • Parametric approaches to quality-adjusted survival analysis
    • Cole BF, Gelber RD, Anderson KM, International Breast Cancer Study Group. Parametric approaches to quality-adjusted survival analysis. Biometrics. 1994;50:621-631.
    • (1994) Biometrics , vol.50 , pp. 621-631
    • Cole, B.F.1    Gelber, R.D.2    Anderson, K.M.3
  • 18
    • 0032524951 scopus 로고    scopus 로고
    • Parametric likelihoods for multiple non-fatal competing risks and death
    • Shen Y, Thall PF. Parametric likelihoods for multiple non-fatal competing risks and death. Stat Med. 1998;17:999-1015.
    • (1998) Stat Med , vol.17 , pp. 999-1015
    • Shen, Y.1    Thall, P.F.2
  • 19
    • 0038312289 scopus 로고    scopus 로고
    • Analysis and reporting of factorial trials: A systematic review
    • McAlister FA, Straus SE, Sackett DL, Altman DG. Analysis and reporting of factorial trials: a systematic review. JAMA. 2003;289:2545-2553.
    • (2003) JAMA , vol.289 , pp. 2545-2553
    • McAlister, F.A.1    Straus, S.E.2    Sackett, D.L.3    Altman, D.G.4
  • 20
    • 0035969564 scopus 로고    scopus 로고
    • Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease
    • Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med. 2001;345:1583-1592.
    • (2001) N Engl J Med , vol.345 , pp. 1583-1592
    • Brown, B.G.1    Zhao, X.Q.2    Chait, A.3
  • 21
    • 0033805348 scopus 로고    scopus 로고
    • Evaluation of the effects of aspirin combined with angiotensin-converting enzyme inhibitors in patients with coronary artery disease
    • Peterson JG, Topol EJ, Sapp SK, Young JB, Lincoff AM, Lauer MS. Evaluation of the effects of aspirin combined with angiotensin-converting enzyme inhibitors in patients with coronary artery disease. Am J Med. 2000;109:371-377.
    • (2000) Am J Med , vol.109 , pp. 371-377
    • Peterson, J.G.1    Topol, E.J.2    Sapp, S.K.3    Young, J.B.4    Lincoff, A.M.5    Lauer, M.S.6
  • 22
    • 0035906289 scopus 로고    scopus 로고
    • CONSORT revised-improving the reporting of randomized trials
    • Rennie D. CONSORT revised-improving the reporting of randomized trials. JAMA. 2001;285:2006-2007.
    • (2001) JAMA , vol.285 , pp. 2006-2007
    • Rennie, D.1
  • 23
    • 0029837588 scopus 로고    scopus 로고
    • How to report randomized controlled trials: The CONSORT statement
    • Rennie D. How to report randomized controlled trials: the CONSORT statement. JAMA. 1996;276:649.
    • (1996) JAMA , vol.276 , pp. 649
    • Rennie, D.1
  • 24
    • 0035827865 scopus 로고    scopus 로고
    • Representation of elderly persons and women in published randomized trials of acute coronary syndromes
    • Lee PY, Alexander KP, Hammill BG, Pasquali SK, Peterson ED. Representation of elderly persons and women in published randomized trials of acute coronary syndromes. JAMA. 2001;286:708-713.
    • (2001) JAMA , vol.286 , pp. 708-713
    • Lee, P.Y.1    Alexander, K.P.2    Hammill, B.G.3    Pasquali, S.K.4    Peterson, E.D.5
  • 25
    • 0034647297 scopus 로고    scopus 로고
    • Primary angioplasty-time is of the essence
    • Lauer MS. Primary angioplasty-time is of the essence. JAMA. 2000;283:2988-2989.
    • (2000) JAMA , vol.283 , pp. 2988-2989
    • Lauer, M.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.