메뉴 건너뛰기




Volumn 17, Issue 2, 2003, Pages 253-262

Current Status of Monoclonal antibody therapy for Chronic Lymphocytic Leukemia

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY;

EID: 0037628994     PISSN: 08909091     EISSN: 08909091     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (64)
  • 2
    • 0016740933 scopus 로고
    • Clinical staging of chronic lymphocytic leukemia
    • Rai KR, Sawitsky A, Cronkite EP, et al: Clinical staging of chronic lymphocytic leukemia. Blood 46:219-234, 1975.
    • (1975) Blood , vol.46 , pp. 219-234
    • Rai, K.R.1    Sawitsky, A.2    Cronkite, E.P.3
  • 3
    • 0034649696 scopus 로고    scopus 로고
    • Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leuemia
    • Rai KR, Peterson BL, Appelbaum FR, et al: Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leuemia. N Engl J Med 343:1750-1757, 2000.
    • (2000) N Engl J Med , vol.343 , pp. 1750-1757
    • Rai, K.R.1    Peterson, B.L.2    Appelbaum, F.R.3
  • 4
    • 0008942168 scopus 로고    scopus 로고
    • Monoclonal antibodies: Basic principles, radioisotope conjugates
    • in Rosenberg SA (ed). Philadelphia, Lip- pincott Williams & WiIkins
    • Larson S, Divgi C, Sgouros G, et al: Monoclonal antibodies: Basic principles, radioisotope conjugates, in Rosenberg SA (ed): Principles and Practice of the Biologic Therapy of Cancer, pp 396-412. Philadelphia, Lip- pincott Williams & WiIkins, 2000.
    • (2000) Principles and Practice of the Biologic Therapy of Cancer , pp. 396-412
    • Larson, S.1    Divgi, C.2    Sgouros, G.3
  • 5
    • 1842595836 scopus 로고    scopus 로고
    • The use of therapeutic monoclonal antibodies in chronic lymphocytic leukemia
    • in Cheson B (ed). New York, Marcel Dekker
    • Dyer M, Osterborg A: The use of therapeutic monoclonal antibodies in chronic lymphocytic leukemia, in Cheson B (ed): Chronic Lymphocytic Leukemias, pp 335-352. New York, Marcel Dekker, 2001.
    • (2001) Chronic Lymphocytic Leukemias , pp. 335-352
    • Dyer, M.1    Osterborg, A.2
  • 6
    • 0036464719 scopus 로고    scopus 로고
    • Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgRIIIa gene
    • Cartron G, Dacheux L, Salles G, et al: Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgRIIIa gene. Blood 99:754-758, 2002.
    • (2002) Blood , vol.99 , pp. 754-758
    • Cartron, G.1    Dacheux, L.2    Salles, G.3
  • 7
    • 0035469885 scopus 로고    scopus 로고
    • Expression of complement inhibitors CD46, CD55, and CD59 on tumor cells does not predict clinical outcome after rituximab treatment in follicular non- Hodgkin lymphoma
    • Weng WK, Levy R: Expression of complement inhibitors CD46, CD55, and CD59 on tumor cells does not predict clinical outcome after rituximab treatment in follicular non- Hodgkin lymphoma. Blood 98:1352-1357, 2001.
    • (2001) Blood , vol.98 , pp. 1352-1357
    • Weng, W.K.1    Levy, R.2
  • 8
    • 0036464611 scopus 로고    scopus 로고
    • The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: Evidence of caspase activation and apoptosis induction
    • Byrd JC, Kitada S, Flinn IW, et al: The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: Evidence of caspase activation and apoptosis induction. Blood 99:1038-1043, 2002.
    • (2002) Blood , vol.99 , pp. 1038-1043
    • Byrd, J.C.1    Kitada, S.2    Flinn, I.W.3
  • 9
    • 0032030699 scopus 로고    scopus 로고
    • Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies
    • Shan D, Ledbetter JA, Press OW: Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies. Blood 91:1644-1652, 1998.
    • (1998) Blood , vol.91 , pp. 1644-1652
    • Shan, D.1    Ledbetter, J.A.2    Press, O.W.3
  • 10
    • 0028057250 scopus 로고
    • Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20
    • Reff ME, Carner K, Chambers KS, et al: Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood 83:435-445, 1994.
    • (1994) Blood , vol.83 , pp. 435-445
    • Reff, M.E.1    Carner, K.2    Chambers, K.S.3
  • 11
    • 0021272605 scopus 로고
    • Expression of human B cell-associated antigens on leukemias and lymphomas: A model of human B cell differentiation
    • Anderson KC, Bates MP, Slaughenhoupt BL, et al: Expression of human B cell-associated antigens on leukemias and lymphomas: A model of human B cell differentiation. Blood 63:1424-1433, 1984.
    • (1984) Blood , vol.63 , pp. 1424-1433
    • Anderson, K.C.1    Bates, M.P.2    Slaughenhoupt, B.L.3
  • 12
    • 0024517986 scopus 로고
    • The gene that encodes the human CD20 (Bl) differentiation antigen is located on chromosome 11 near the t(l I;14)(ql3;q32) translocation site
    • Tedder TF, Disteche CM, Louie E, et al: The gene that encodes the human CD20 (Bl) differentiation antigen is located on chromosome 11 near the t(l I;14)(ql3;q32) translocation site. J Immunol 142:2555-2559, 1989.
    • (1989) J Immunol , vol.142 , pp. 2555-2559
    • Tedder, T.F.1    Disteche, C.M.2    Louie, E.3
  • 13
    • 0023672444 scopus 로고
    • Isoation and structure of a cDNA encoding the Bl (CD20) cell-surface antigen of human B lymphocytes
    • 13, Tedder TF, Streuli M, Schlossman SF, et ak'Isoâtion and structure of a cDNA encoding the Bl (CD20) cell-surface antigen of human B lymphocytes. Proc Natl Acad Sci USA 85:208-212, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 208-212
    • Tedder, T.F.1    Streuli, M.2    Et Al., S.Sf.3
  • 15
    • 0345337254 scopus 로고    scopus 로고
    • Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four- dose treatment program
    • McLaughlin P, Grillo-Lopez AJ, Link BK, et al: Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four- dose treatment program. J Clin Oncol 16:2825-2833, 1998.
    • (1998) J Clin Oncol , vol.16 , pp. 2825-2833
    • McLaughlin, P.1    Grillo-Lopez, A.J.2    Link, B.K.3
  • 16
    • 0033067232 scopus 로고    scopus 로고
    • Single-agent monoclonal antibody efficacy in bulky non-Hodgkin's lymphoma: Results of a phase II trial of rituximab
    • Davis TA, White CA, Grillo-Lopez AJ, et al: Single-agent monoclonal antibody efficacy in bulky non-Hodgkin's lymphoma: Results of a phase II trial of rituximab. J Clin Oncol 17:1851-1857, 1999.
    • (1999) J Clin Oncol , vol.17 , pp. 1851-1857
    • Davis, T.A.1    White, C.A.2    Grillo-Lopez, A.J.3
  • 17
    • 0003257593 scopus 로고    scopus 로고
    • Phase II study of Rituximab (Rituxan) in patients with previously untreated low-grade or follicular non-Hodgkin's lymphoma (abstract 79)
    • Gutheil J, Finucane D, Rodriguez R, et al: Phase II study of Rituximab (Rituxan) in patients with previously untreated low-grade or follicular non-Hodgkin's lymphoma (abstract 79). Proc Am Soc Clin Oncol 19:22a, 2000.
    • (2000) Proc Am Soc Clin Oncol , vol.19
    • Gutheil, J.1    Finucane, D.2    Rodriguez, R.3
  • 18
    • 0003337593 scopus 로고    scopus 로고
    • Toxicity and efficacy of the anti-CD20 antibody rituximab (Rituxan) in patients with B-cell chronic lymphocytic leukemia: A phase 1/ II study (abstract 1396
    • Winkler U, Schulz H, Jensen M, et al: Toxicity and efficacy of the anti-CD20 antibody rituximab (Rituxan) in patients with B- cell chronic lymphocytic leukemia: A phase 1/ II study (abstract 1396). Blood 94:312a, 1999.
    • (1999) Blood , vol.94
    • Winkler, U.1    Schulz, H.2    Jensen, M.3
  • 19
    • 0035469851 scopus 로고    scopus 로고
    • Rituximab therapy of patients with B-cell chronic lymphocytic leukemia
    • Huhn D, von Schilling C, Wilhelm M, et al: Rituximab therapy of patients with B-cell chronic lymphocytic leukemia. Blood 98:1326-1331, 2001.
    • (2001) Blood , vol.98 , pp. 1326-1331
    • Huhn, D.1    Von Schilling, C.2    Wilhelm, M.3
  • 20
    • 0035871441 scopus 로고    scopus 로고
    • Rituximab dose-escalation trial in chronic lymphocytic leukemia
    • O'Brien SM, Kantarjian H, Thomas DA, et al: Rituximab dose-escalation trial in chronic lymphocytic leukemia. J Clin Oncol 19:2165-2170, 2001.
    • (2001) J Clin Oncol , vol.19 , pp. 2165-2170
    • O'Brien, S.M.1    Kantarjian, H.2    Thomas, D.A.3
  • 21
    • 0035871445 scopus 로고    scopus 로고
    • Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity
    • Byrd JC, Murphy T, Howard RS, et al: Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity. J Clin Oncol 19:2153-2164, 2001.
    • (2001) J Clin Oncol , vol.19 , pp. 2153-2164
    • Byrd, J.C.1    Murphy, T.2    Howard, R.S.3
  • 22
    • 0037108822 scopus 로고    scopus 로고
    • Rituximab as first-line and maintenance therapy for patients with small lymphocytic lymphoma (SLL) and chronic lymphocytic leukemia (CLL) (abstract 1530
    • Hainsworth J, Litchy S, Burris H, et al: Rituximab as first-line and maintenance therapy for patients with small lymphocytic lymphoma (SLL) and chronic lymphocytic leukemia (CLL) (abstract 1530). J Clin Oncol 20:4261-4267, 2002.
    • (2002) J Clin Oncol , vol.20 , pp. 4261-4267
    • Hainsworth, J.1    Litchy, S.2    Burris, H.3
  • 23
    • 0032931320 scopus 로고    scopus 로고
    • IDEC-C2B8 anti-CD20 (rituximab) immunotherapy in patients with low-grade non- Hodgkin's lymphoma and lymphoproliferative disorders: Evaluation of response on 48 patients
    • Nguyen DT, Amess JA, Doughty H, et al: IDEC-C2B8 anti-CD20 (rituximab) immunotherapy in patients with low-grade non- Hodgkin's lymphoma and lymphoproliferative disorders: evaluation of response on 48 patients. Eur J Haematol 62:76-82, 1999.
    • (1999) Eur J Haematol , vol.62 , pp. 76-82
    • Nguyen, D.T.1    Amess, J.A.2    Doughty, H.3
  • 24
    • 0006937912 scopus 로고    scopus 로고
    • Clinical relevance of circulating CD 20 (cCD 20) in patients with chronic lymphocytic leukemia (CLL) (abstract 1595
    • Manshouri T, SafferH, Keating M: Clinical relevance of circulating CD 20 (cCD 20) in patients with chronic lymphocytic leukemia (CLL) (abstract 1595). Blood 96:369a, 2000.
    • (2000) Blood , vol.96
    • Manshouri, T.1    Safferh Keating, M.2
  • 25
    • 0034575137 scopus 로고    scopus 로고
    • Rituximab therapy of B-cell neoplasms
    • Petryk M, Grossbard M: Rituximab therapy of B-cell neoplasms. Clin Lymphoma 1:186-194, 2000.
    • (2000) Clin Lymphoma , vol.1 , pp. 186-194
    • Petryk, M.1    Grossbard, M.2
  • 26
    • 0000120413 scopus 로고    scopus 로고
    • Ritux- imab/cyclophosphomide/dexamethasone combination highly effective in autoimmune hemolytic anemia associated with chronic lymphocytic leukemia (abstract 3264
    • Rai K, Gupta N, Janson D, et al: Ritux- imab/cyclophosphomide/ dexamethasone combination highly effective in autoimmune hemolytic anemia associated with chronic lymphocytic leukemia (abstract 3264). Blood 96:754a, 2000.
    • (2000) Blood , vol.96
    • Rai, K.1    Gupta, N.2    Janson, D.3
  • 27
    • 79960970956 scopus 로고    scopus 로고
    • Re- treatment with a rituximab based therapy is highly effective in autoimmune hemolytic anemia (AIHA) associated with chronic lymphocytic leukemia (CLL) (abstract 1529
    • Gupta N, Patel D, Kavuru S, et al: Re- treatment with a rituximab based therapy is highly effective in autoimmune hemolytic anemia (AIHA) associated with chronic lymphocytic leukemia (CLL) (abstract 1529). Blood 98:363a, 2001.
    • (2001) Blood , vol.98
    • Gupta, N.1    Patel, D.2    Kavuru, S.3
  • 28
    • 0033016566 scopus 로고    scopus 로고
    • Rituximab therapy in hematologic malignancy patients with circulating blood tumor cells: Association with increased infusion-related side effects and rapid blood tumor clearance
    • Byrd JC, Waselenko JK, ManeatisXI, et al: Rituximab therapy in hematologic malignancy patients with circulating blood tumor cells: Association with increased infusion-related side effects and rapid blood tumor clearance. J Clin Oncol 17:791-795, 1999.
    • (1999) J Clin Oncol , vol.17 , pp. 791-795
    • Byrd, J.C.1    Maneatisxi W.Jk2
  • 29
    • 0032736341 scopus 로고    scopus 로고
    • Tumor lysis syndrome occurring after the administration of rituximab in lymphoproliferative disorders: High-grade non-Hodgkin's lymphoma and chronic lymphocytic leukemia
    • Yang H, Rosove MH, Figlin RA: Tumor lysis syndrome occurring after the administration of rituximab in lymphoproliferative disorders: High-grade non-Hodgkin's lymphoma and chronic lymphocytic leukemia. Am J He- matol 62:247-250, 1999.
    • (1999) Am J Hematol , vol.62 , pp. 247-250
    • Yang, H.1    Rosove, M.H.2    Figlin, R.A.3
  • 30
    • 0032719863 scopus 로고    scopus 로고
    • Preclinical and phase i and II trials of rituximab
    • Maloney DG: Preclinical and phase I and II trials of rituximab. Semin Oncol 26:74-78, 1999.
    • (1999) Semin Oncol , vol.26 , pp. 74-78
    • Maloney, D.G.1
  • 31
    • 0024566393 scopus 로고
    • Effects of CAMPATH-I antibodies in vivo in patients with lymphoid malignancies: Influence of antibody isotype
    • Dyer MJ, Hale G, Hayhoe FG, et al: Effects of CAMPATH-I antibodies in vivo in patients with lymphoid malignancies: Influence of antibody isotype. Blood 73:1431-1439, 1989.
    • (1989) Blood , vol.73 , pp. 1431-1439
    • Dyer, M.J.1    Hale, G.2    Hayhoe, F.G.3
  • 32
  • 33
    • 0023911111 scopus 로고
    • Reshaping human antibodies for therapy
    • Riechmann L, Clark M, Waldmann H, et al: Reshaping human antibodies for therapy. Nature 332:323-327, 1988.
    • (1988) Nature , vol.332 , pp. 323-327
    • Riechmann, L.1    Clark, M.2    Waldmann, H.3
  • 34
    • 0024204319 scopus 로고
    • Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1 H
    • Hale G, Dyer MJ, Clark MR, et al: Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1 H. Lancet 2:1394-1399, 1988.
    • (1988) Lancet , vol.2 , pp. 1394-1399
    • Hale, G.1    Dyer, M.J.2    Clark, M.R.3
  • 35
    • 0027240401 scopus 로고
    • Effect of Cam- path-lH antibody on human hematopoietic progenitors in vitro
    • Gilleece MH, Dexter TM: Effect of Cam- path-lH antibody on human hematopoietic progenitors in vitro. Blood 82:807-812, 1993.
    • (1993) Blood , vol.82 , pp. 807-812
    • Gilleece, M.H.1    Dexter, T.M.2
  • 36
    • 0028352208 scopus 로고
    • Immunohistochemical analysis of CDw52 antigen expression in non-Hodgkin's lymphomas
    • Salisbury JR, Rapson NT, Codd JD, et al: Immunohistochemical analysis of CDw52 antigen expression in non-Hodgkin's lymphomas. J Clin Pathol 47:313-317, 1994.
    • (1994) J Clin Pathol , vol.47 , pp. 313-317
    • Salisbury, J.R.1    Rapson, N.T.2    Codd, J.D.3
  • 37
    • 0031757274 scopus 로고    scopus 로고
    • CAMPATH-1 H monoclonal antibody in therapy for previously treated low-grade non- Hodgkin's lymphomas: A phase II multicenter study
    • European Study Group of CAMPATH- 1H Treatment in Low-Grade Non-Hodgkin's Lymphoma
    • Lundin J, Osterborg A, Brittinger G, et al: CAMPATH-1 H monoclonal antibody in therapy for previously treated low-grade non- Hodgkin's lymphomas: A phase II multicenter study. European Study Group of CAMPATH- 1H Treatment in Low-Grade Non-Hodgkin's Lymphoma. J Clin Oncol 16:3257-3263, 1998.
    • (1998) J Clin Oncol , vol.16 , pp. 3257-3263
    • Lundin, J.1    Osterborg, A.2    Brittinger, G.3
  • 38
    • 0027537357 scopus 로고
    • Differential response in a patient treated with Campath- IH monoclonal antibody for refractory non-Hodgkin lymphoma
    • Lim SH, Davey G, Marcus R: Differential response in a patient treated with Campath- IH monoclonal antibody for refractory non-Hodgkin lymphoma. Lancet 341:432-433, 1993.
    • (1993) Lancet , vol.341 , pp. 432-433
    • Lim, S.H.1    Davey, G.2    Marcus, R.3
  • 39
    • 0030812012 scopus 로고    scopus 로고
    • Treatment of T-cell prolymphocytic leukemia with human CD52 antibody
    • Pawson R, Dyer MJ, Barge R, et al: Treatment of T-cell prolymphocytic leukemia with human CD52 antibody. J Clin Oncol 15:2667-2672, 1997.
    • (1997) J Clin Oncol , vol.15 , pp. 2667-2672
    • Pawson, R.1    Dyer, M.J.2    Barge, R.3
  • 40
    • 0035885965 scopus 로고    scopus 로고
    • High remission rate in T-cell prolymphocytic leukemia with CAMPATH-1H
    • Dearden CE, Matutes E, Cazin B, et al: High remission rate in T-cell prolymphocytic leukemia with CAMPATH-1H. Blood 98:1721-1726, 2001.
    • (2001) Blood , vol.98 , pp. 1721-1726
    • Dearden, C.E.1    Matutes, E.2    Cazin, B.3
  • 41
    • 0030897222 scopus 로고    scopus 로고
    • Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia
    • European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia
    • Osterborg A, Dyer MJ, Bunjes D, et al: Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia. J Clin Oncol 15:1567-1574, 1997.
    • (1997) J Clin Oncol , vol.15 , pp. 1567-1574
    • Osterborg, A.1    Dyer, M.J.2    Bunjes, D.3
  • 42
    • 0037092951 scopus 로고    scopus 로고
    • Multi-center study of CAMPATH-1H in patients with chronic lymphocytic leukemia refractory to fludarabine
    • Keating M, Byrd J, Rai K, et al: Multi- center study of CAMPATH-1H in patients with chronic lymphocytic leukemia refractory to flu- darabine. Blood 99:3554-3561, 2002.
    • (2002) Blood , vol.99 , pp. 3554-3561
    • Keating, M.1    Byrd, J.2    Rai, K.3
  • 43
    • 0000470701 scopus 로고    scopus 로고
    • Campath-IH therapy in 29 patients with refractory CLL: True complete remission in an attainable goal (abstract 2683)
    • Kennedy B, Rawstron A, Evans P, et al: Campath-IH therapy in 29 patients with refractory CLL: True complete remission in an attainable goal (abstract 2683). Blood 94:603a, 1999.
    • (1999) Blood , vol.94
    • Kennedy, B.1    Rawstron, A.2    Evans, P.3
  • 44
    • 79960971484 scopus 로고    scopus 로고
    • Efficacy and safety of almetuzumab (campath-1H) in refractory B-CLL patients treated on a compassionate basis (abstract 1538)
    • Rai K, Coutre S, Rizzieri D, et al: Efficacy and safety of almetuzumab (campath-1H) in refractory B-CLL patients treated on a compassionate basis (abstract 1538). Blood 98:365a, 2001.
    • (2001) Blood , vol.98
    • Rai, K.1    Coutre, S.2    Rizzieri, D.3
  • 45
    • 0029937765 scopus 로고    scopus 로고
    • Anagnostopoulos A, et al: Humanized CD52 monoclonal antibody Campath-IH as first-line treatment in chronic lymphocytic leukaemia
    • Osterborg A, Fassas AS, Anagnostopoulos A, et al: Humanized CD52 monoclonal antibody Campath-IH as first-line treatment in chronic lymphocytic leukaemia. Br J Haematol 93:151-153, 1996.
    • (1996) Br J Haematol , vol.93 , pp. 151-153
    • Osterborg, A.1    Fassas, A.S.2
  • 46
    • 0031027623 scopus 로고    scopus 로고
    • Subcutaneous CAMPATH-IH in fludarabine- resistant/relapsed chronic lymphocytic and B- prolymphocytic leukaemia
    • Bowen AL, Zomas A, Emmett E, et al: Subcutaneous CAMPATH-IH in fludarabine- resistant/relapsed chronic lymphocytic and B- prolymphocytic leukaemia. Br J Haematol 96:617-619, 1997.
    • (1997) Br J Haematol , vol.96 , pp. 617-619
    • Bowen, A.L.1    Zomas, A.2    Emmett, E.3
  • 47
    • 0030300084 scopus 로고    scopus 로고
    • Immunosuppressive toxicity of CAMPATH IH monoclonal antibody in the treatment of patients with recurrent low grade lymphoma
    • Tang SC, Hewitt K, Reis MD, et al: Immunosuppressive toxicity of CAMPATH IH monoclonal antibody in the treatment of patients with recurrent low grade lymphoma. Leak Lymphoma 24:93-101, 1996.
    • (1996) Leak Lymphoma , vol.24 , pp. 93-101
    • Tang, S.C.1    Hewitt, K.2    Reis, M.D.3
  • 48
    • 0037524970 scopus 로고    scopus 로고
    • Incidence of cytomegalovirus (CMV) viremia during campath-1H therapy for relapsed/refractory chronic lymphocytic leukemia (CLL) and prolymphocytic leukemia (PLL) (abstract 1540
    • Thai C, Nguyen D, Dugan K, et al: Incidence of cytomegalovirus (CMV) viremia during campath-1H therapy for relapsed/refractory chronic lymphocytic leukemia (CLL) and prolymphocytic leukemia (PLL) (abstract 1540). Blood 98:366a, 2001.
    • (2001) Blood , vol.98
    • Thai, C.1    Nguyen, D.2    Dugan, K.3
  • 49
    • 15844368449 scopus 로고    scopus 로고
    • Multicentre prospective randomised trial of flu- darabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia
    • The French Cooperative Group on CLL
    • Johnson S, Smith AG, Loffler H, et al: Multicentre prospective randomised trial of flu- darabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. The French Cooperative Group on CLL. Lancet 347:1432-1438, 1996.
    • (1996) Lancet , vol.347 , pp. 1432-1438
    • Johnson, S.1    Smith, A.G.2    Loffler, H.3
  • 50
    • 0037220152 scopus 로고    scopus 로고
    • Concurrent rituximab and fludarabine has a higher complete response rate than sequential treatment in untreated chronic lymphocytic leukemia (CLL) patients: Results from CALGB 9712
    • Byrd J, Peterson B, Park K, et al: Concurrent rituximab and fludarabine has a higher complete response rate than sequential treatment in untreated chronic lymphocytic leukemia (CLL) patients: Results from CALGB 9712. Blood 101:6-14, 2003.
    • (2003) Blood , vol.101 , pp. 6-14
    • Byrd, J.1    Peterson, B.2    Park, K.3
  • 51
    • 79960970593 scopus 로고    scopus 로고
    • Phase II study of rituximab in combination with fludarabine in patients with chronic lymphocytic leukemia (CLL) (abstract 1534
    • Schulz H, Klein S, Rehwald U, et al: Phase II study of rituximab in combination with fludarabine in patients with chronic lymphocytic leukemia (CLL) (abstract 1534). Blood 98:364a, 2001.
    • (2001) Blood , vol.98
    • Schulz, H.1    Klein, S.2    Rehwald, U.3
  • 52
    • 0035179950 scopus 로고    scopus 로고
    • DNA repair initiated in chronic lymphocytic leukemia lymphocytes by 4-hydroperoxy- cyclophosphamide is inhibited by fludarabine and clofarabine
    • Yamauchi T, Nowak BJ, Keating MJ, et al: DNA repair initiated in chronic lymphocytic leukemia lymphocytes by 4-hydroperoxy- cyclophosphamide is inhibited by fludarabine and clofarabine. Clin Cancer Res 7:3580-3589, 2001.
    • (2001) Clin Cancer Res , vol.7 , pp. 3580-3589
    • Yamauchi, T.1    Nowak, B.J.2    Keating, M.J.3
  • 53
    • 0035282055 scopus 로고    scopus 로고
    • Results of the fludarabine and cyclophosphamide combination regimen in chronic lymphocytic leukemia
    • O'Brien SM, Kantarjian HM, Cortes J, et al: Results of the fludarabine and cyclophosphamide combination regimen in chronic lymphocytic leukemia. J Clin Oncol 19:1414- 1420, 2001.
    • (2001) J Clin Oncol , vol.19 , pp. 1414-1420
    • O'Brien, S.M.1    Kantarjian, H.M.2    Cortes, J.3
  • 54
    • 79960971391 scopus 로고    scopus 로고
    • Update of results of fludarabine, cyclophosphamide, and rituximab for previously treated patients with chronic lymphocytic leukemia (CLL) (abstract 2650)
    • Garcia-Manero G, O'Brien S, Cortes J, et al: Update of results of fludarabine, cyclophosphamide, and rituximab for previously treated patients with chronic lymphocytic leukemia (CLL) (abstract 2650). Blood 98:633a, 2001.
    • (2001) Blood , vol.98
    • Garcia-Manero, G.1    O'Brien, S.2    Cortes, J.3
  • 55
    • 79960970873 scopus 로고    scopus 로고
    • Combined fludarabine, cyclophosphamide, and rituximab achieves a high complete remission rate as initial treatment for chronic lymphocytic leukemia (abstract 3210)
    • Wierda W, O'Brien S, Albitar M, et al: Combined fludarabine, cyclophosphamide, and rituximab achieves a high complete remission rate as initial treatment for chronic lymphocytic leukemia (abstract 3210). Blood 2001; 98:771a, 2001.
    • (2001) Blood , vol.98
    • Wierda, W.1    O'Brien, S.2    Albitar, M.3
  • 56
    • 0034198736 scopus 로고    scopus 로고
    • Pentostatin and rituximab in the treatment of patients with B-cell malignancies
    • Drapkin R: Pentostatin and rituximab in the treatment of patients with B-cell malignancies. Oncology 14:25-29, 2000.
    • (2000) Oncology , vol.14 , pp. 25-29
    • Drapkin, R.1
  • 57
    • 0000336409 scopus 로고    scopus 로고
    • CAMPATH-IH with fludarabine: A novel, highly active combination in refractory CLL (abstract 703)
    • Kennedy B, Rawstron A, Carter C, et al: CAMPATH-IH with fludarabine: A novel, highly active combination in refractory CLL (abstract 703). Blood 96:289b, 2000.
    • (2000) Blood , vol.96
    • Kennedy, B.1    Rawstron, A.2    Carter, C.3
  • 58
    • 0037085770 scopus 로고    scopus 로고
    • Campath-IH and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia
    • Kennedy B, Rawstron A, Carter C, et al: Campath-IH and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia. Blood 99:2245-2247, 2002.
    • (2002) Blood , vol.99 , pp. 2245-2247
    • Kennedy, B.1    Rawstron, A.2    Carter, C.3
  • 59
    • 0036179094 scopus 로고    scopus 로고
    • Conceptual aspects of combining rituximab and Campath- IH in the treatment of chronic lymphocytic leukemia
    • Nabhan C, Rosen ST: Conceptual aspects of combining rituximab and Campath- IH in the treatment of chronic lymphocytic leukemia. Semln Oncol 29:75-80, 2002.
    • (2002) Semln Oncol , vol.29 , pp. 75-80
    • Nabhan, C.1    Rosen, S.T.2
  • 60
    • 79960970604 scopus 로고    scopus 로고
    • Phase i study of rituximab and CAMPATH-IH in patients with relapsed or refractory chronic lymphocytic leukemia (abstract 1536
    • Nabhan C, Tallman M, Riley M, et al: Phase I study of rituximab and CAMPATH-IH in patients with relapsed or refractory chronic lymphocytic leukemia (abstract 1536). Blood 98:365a, 2001.
    • (2001) Blood , vol.98
    • Nabhan, C.1    Tallman, M.2    Riley, M.3
  • 61
    • 79960971710 scopus 로고    scopus 로고
    • An exploratory study of the combination of monoclonal antibodies CAMPATH-1H and rituximab in the treatment of CD 52 and CD 20 positive chronic lymphoid disorders (abstract 1537)
    • Faderl S, Thomas D, O'Brien S, et al: An exploratory study of the combination of monoclonal antibodies CAMPATH-1H and rituximab in the treatment of CD 52 and CD 20 positive chronic lymphoid disorders (abstract 1537). Blood 98:365a, 2001.
    • (2001) Blood , vol.98
    • Faderl, S.1    Thomas, D.2    O'Brien, S.3
  • 62
    • 79960971026 scopus 로고    scopus 로고
    • Combination monoclonal antibody therapy for lymphoma treatment with epratuzumab (anti-CD 22) and rituximab (anti-CD 20) is well tolerated (abstract 3506)
    • Leonard J, Coleman M, Matthews J, et al: Combination monoclonal antibody therapy for lymphoma treatment with epratuzumab (anti-CD 22) and rituximab (anti-CD 20) is well tolerated (abstract 3506). Blood 98:844a, 2001.
    • (2001) Blood , vol.98
    • Leonard, J.1    Coleman, M.2    Matthews, J.3
  • 63
    • 79960970576 scopus 로고    scopus 로고
    • A phase II study of Remitogen (HulDIO), a humanized monoclonal antibody in patients with relapsed or refractory follicular, small lymphocytic, or marginal zone/MALT B-cell lymphoma (abstract 2540)
    • Link B, Kahl B, Czuczman M, et al: A phase II study of Remitogen (HulDIO), a humanized monoclonal antibody in patients with relapsed or refractory follicular, small lymphocytic, or marginal zone/MALT B-cell lymphoma (abstract 2540). Blood 98:606a, 2001.
    • (2001) Blood , vol.98
    • Link, B.1    Kahl, B.2    Czuczman, M.3
  • 64
    • 79951658129 scopus 로고    scopus 로고
    • Single agent rituxan in early stage chronic lymphocytic leukemia (CLL) (abstract 1533
    • Thomas D, O'Brien S, Giles F: Single agent rituxan in early stage chronic lymphocytic leukemia (CLL) (abstract 1533). Blood 98:364a, 2001.
    • (2001) Blood , vol.98
    • Thomas, D.1    O'Brien, S.2    Giles, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.