Repetitive preischemic infusion of phosphodiesterase III inhibitor olprinone elicits cardio-protective effects in the failing heart after myocardial infarction

Molecular and Cellular Biochemistry

Volumn 248, Issue 1-2, 2003, Pages 179-184

  Nomura, Yukiya ^a   Horimoto, Hitoshi ^a   Mieno, Shigetoshi ^a   Nakahara, Ken Ichi ^a   Okawa, Hirohisa ^a   Yoshida, Masataka ^a   Sasaki, Shinjiro ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Beta adrenergic receptor; cAMP; Failing heart; Ischemic preconditioning; Phosphodiesterase II inhibitor

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; HEPARIN; LOPRINONE; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PENTOBARBITAL; PHOSPHODIESTERASE INHIBITOR;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HEART FAILURE; HEART INFARCTION; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE PRESSURE; HEART PERFUSION; HEART PROTECTION; IN VIVO STUDY; ISOLATED HEART; MALE; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; CORONARY CIRCULATION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HEART; HEART VENTRICLES; IMIDAZOLES; ISCHEMIA; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; PERFUSION; PHOSPHODIESTERASE INHIBITORS; PRESSURE; PYRIDONES; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS;

ANIMALIA;

EID: 0037627914     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024100722413     Document Type: Article

References (21)

1. Murry CE, Jennings RB, Reimer KA: Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium. Circulation 74: 1124-1136, 1986
2. Downey JM: Ischemic preconditioning nature's own cardioprotective intervention. Trans Cardiovasc Med 2: 170-175, 1992
3. Sandhu R, Thomas U, Diaz RJ, Wilson GJ; Effects of ischemic preconditioning of the myocardium on cAMP. Circ Res 78: 137-147, 1996
4. Lochner A, Genade S, Tromp E, Opie L, Moolman JA, Thomas S, Podzuweit T: Role of cyclic nucleotide phosphodiesterases in ischemic preconditioning. Mol Cell Biochem 186: 169-175, 1998
5. Okruhlicova L, Ravingerova T, Pancza D, Tribulova N, Stuk J, Stetka R: Activation of adenylate cyclase system in the preconditioned rat heart. Physiol Res 49: 251-259, 2000
6. Saltman AE, Gaudette GE, Levitsky S, Kurukenkamp IB: Amrinone preconditioning in the isolated perfused rabbit heart. Ann Thorac Surg 102: 609-613, 2000
7. Sanada S, Kitakaze M, Papst PJ, Asanuma H, Node K, Takashima S, Asakura M, Ogita H, Liao Y, Sakata Y, Ogai Y, Fukushima T, Yamada J, Shinozaki Y, Kuzuya T, Mori H, Terada N, Hori M: Cardioprotective effect afford by transient exposure to phosphodiesterase III inhibitors. Circulation 104: 705-710, 2001
8. Miki T, Miura T, Tsuchida A: Cardioprotective mechanism of ischemic preconditioning is impaired by postinfarct ventricular remodeling through angiotensin II type 1 receptor activation. Circulation 102: 458-463, 2000
9. Lefkowitz RJ, Rockman HA, Koch WJ: Catecholamines, cardiac beta-adrenergic receptors, and heart failure. Circulation 101: 1634-1637, 2000
10. Selye H, Bajusz E, Grasso S, Mendell P: Simple techniques for the surgical occlusion of coronary vessels in the rat. Angiology 11: 398-407, 1960
11. Ausubel FM: In: R. Brent, R.E. Kingston, D.E. Moore, J.G. Seidman, K. Struhi (eds). Current Protocols in Molecular Biology. John Wiley and Son's Inc., New York, 1993, pp 4.2.4-4.2.8
12. Bristow MR: Changes in myocardial and vascular receptors in heart failure. J Am Coll Cardiol 22(suppl A): 61A-71A, 1993
13. 1-adrenoceptor density. Int J Cardiol 72: 137-141, 2000
14. Lochner A, Genade S, Tromp E, Podzuweit T, Moolman JA: Ischemic preconditioning and the β-adrenergic signal transduction pathway. Circulation 100: 958-966, 1999
15. Dixon RA, Kobilka BK, Strader DJ, Benovic JL, Dohlman HG, Frielle T, Bolanowski MA, Bennett CD, Rands E, Diehl RE: Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin. Nature 321: 75-79, 1996
16. Yarden Y, Rodriguez H, Wong SK, Brandt DR, May DC, Brunier J, Harkins RN, Chen EY, Ramachandran J, Ullrich A: The avian β-adrenergic receptor: Primary structure and membrane topology. Proc Natl Acad Sci USA 83: 6795-6799, 1986
17. Sanada S, Kitakaze M, Papst PJ, Hatanaka K, Asanuma H, Aki T, Shinozki Y, Ogita H, Node K, Takashima S, Asakura M, Yamada J, Fukushima T, Ogai A, Kuzuya T, Mori H, Terada N, Yoshida K, Hori M: Role of phasic dynamism of p38 mitogen-activated protein kinase activation in ischemic preconditioning of the canine heart. Circ Res 88: 175-180, 2001
18. Saxena M, Williams S, Tasken K, Mustelin T: Cross talk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphate. Nat Cell Biol 1: 305-311, 1999
19. Blanco-Aparicio C, Torres J, Pulido R: A novel regulatory mechanism of MAP kinase activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphate. J Cell Biol 147: 1129-1136, 1999
20. Brooks G, Hearse DJ: Role of protein kinase C in ischemic preconditioning: player or spectator? Circ Res 79: 627-630, 1996
21. Zimkhovich BZ, Przyklenk K, Kloner RA: Role of protein kinase C as a cellular mediator of ischemic preconditioning: A critical review. Cardiovasc Res 40: 9-22, 1998