Enhanced anti-inflammatory potency of a nitric oxide-releasing prednisolone derivative in the rat

British Journal of Pharmacology

Volumn 139, Issue 5, 2003, Pages 966-972

  Turesin, Fusun ^a   Del Soldato, Piero ^b   Wallace, John L ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b NicOx SA   (France)

Author keywords

Cyclooxygenase; Glucocorticoid; Inflammation; Leukocyte; Leukotriene; Nitric oxide; Prostaglandin

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; CARRAGEENAN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GLUCOCORTICOID; LEUKOTRIENE B4; NCX 1015; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; NITRITE; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISOLONE; PREDNISOLONE DERIVATIVE; PROSTAGLANDIN E2;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; LEUKOCYTE COUNT; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ADJUVANTS, PHARMACEUTIC; ANIMALS; ANTI-INFLAMMATORY AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; NITRIC OXIDE; PREDNISOLONE; RATS; RATS, WISTAR;

EID: 0037622969     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705324     Document Type: Article

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