Aspirin use is associated with higher serum concentrations of the anti-oxidant enzyme, paraoxonase-1 [2]

Diabetologia

Volumn 46, Issue 4, 2003, Pages 593-594

  Blatter Garin, M C ^a   Kalix, B ^a   De Pree, S ^a   James, R W ^a  

^a UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ARYLDIALKYLPHOSPHATASE;

ADULT; AGED; ANTIOXIDANT ACTIVITY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DRUG EFFECT; DRUG USE; ENZYME ACTIVITY; FEMALE; HUMAN; LETTER; LIPID OXIDATION; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL;

AGED; ARYLDIALKYLPHOSPHATASE; ASPIRIN; FEMALE; HUMANS; MALE; MIDDLE AGED;

EID: 0037617740     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (8)

1. Mackness MI, Mackness B, Durrington PN et al. (1998) Paraoxonase and coronary heart disease. Curr Opin Lipidol 9:319-324
2. Abbott CA, Mackness MI, Kumar S, Boulton AJ, Durrington PN (1995) Serum paraoxonase activity, concentration, and phenotype distribution in diabetes mellitus and its relationship to serum lipids and lipoproteins. Arterioscler Thromb Vasc Biol 15:1812-1818
3. Boemi M, Leviev I, Sirolla C, Pieri C, Marra M, James RW (2001) Serum paraoxonase is reduced in type 1 diabetic patients compared to non-diabetic, first degree relatives; influence on the ability of HDL to protect LDL from oxidation. Atherosclerosis 155:229-235
4. Barbieri M, Bonafe M, Marfella R et al. (2002) LL-paraoxonase genotype is associated with a more severe degree of homeostasis model assessment IR in healthy subjects. J Clin Endocrinol Metab 87:222-225
5. Deakin S, Leviev I, Nicaud V, Brulhart Meynet MC, Tiret L, James RW (2002) Paraoxonase-1 L55M polymorphism is associated with an abnormal oral glucose tolerance test and differentiates high risk coronary disease families. J Clin Endocrinol Metab 87:1268-1273
6. Awtry EH, Loscalzo J (2000) Aspirin. Circulation 101:1206-1218
7. Durrington PN, Mackness B, Mackness MI (2002) The hunt for nutritional and pharmacological modulators of paraoxonase. Arterioscler Thromb Vasc Biol 22:1248-1250
8. James RW, Leviev I, Righetti A (2000) Smoking is associated with reduced serum paraoxonase activity and concentration in coronary artery disease patients. Circulation 101:2252-2257