The A1 and A2 subunits of factor VIIIa synergistically stimulate factor IXa catalytic activity

Journal of Biological Chemistry

Volumn 274, Issue 22, 1999, Pages 15401-15406

  Fay, Philip J ^a,b   Koshibu, Kyoko ^a   Mastri, Maria ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 8A; BLOOD CLOTTING FACTOR 9A; HIRUDIN; MONOCLONAL ANTIBODY; RECOMBINANT BLOOD CLOTTING FACTOR 8; SYNTHETIC PEPTIDE;

ANISOTROPY; ARTICLE; BLOOD CLOTTING; CATALYSIS; ENZYME SUBUNIT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANTIBODIES; BINDING SITES; ENZYME ACTIVATION; FACTOR IXA; FACTOR VIII; FACTOR VIIIA; FACTOR X; FACTOR XA; FLUORESCENCE POLARIZATION; HUMANS; KINETICS; RECOMBINANT PROTEINS;

FELIS CATUS;

EID: 0032983331     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.22.15401     Document Type: Article

References (32)

1. Lollar, P., and C. G. Parker. (1989) Biochemistry 28, 666-674
2. Fay, P. J., Haidaris, P. J., and Smudzin, T. M. (1991) J. Biol. Chem. 266, 8957-8962
3. Pittman, D. D., Millenson, M., Marquette, K., Bauer, K., and Kaufman, R. J. (1992) Blood 79, 389-397
4. Lollar, P., Parker, E. T., and Fay, P. J. (1992) J. Biol. Chem. 267, 23652-23657
5. Fay, P. J., and Smudzin, T. M. (1992) J. Biol. Chem. 267, 13246-13250
6. Persson, E., Ezban, M., and Shymko, R. M. (1995) Biochemistry 34, 12775-12781
7. Fay, P. J., Smudzin, T. M., and Walker, F. J. (1991) J. Biol. Chem. 266, 20139-20145
8. Lenting, P. J., Donath, M. J., van Mourik, J. A., and Mertens, K. (1994) J. Biol. Chem. 269, 7150-7155
9. Duffy, E. J., Parker, E. T., Mutucumarana, V. P., Johnson, A. E., and Lollar, P. (1992) J. Biol. Chem. 267, 17006-17011
10. Curtis, J. E., S. L. Helgerson, Parker, E. T., and Lollar, P. (1994) J. Biol. Chem. 289, 6246-6251
11. Lenting, P. J., van de Loo, J. W., Donath, M. J., van Mourik, J. A., and Mertens, K. (1996) J. Biol. Chem. 271, 1935-1940
12. Regan, L. M., Lamphear, B. J., Huggins, C. F., Walker, F. J., and Fay, P. J. (1994) J. Biol. Chem. 269, 9445-9452
13. Fay, P. J., Beattie, T., Huggins, C. F., and Regan, L. M. (1994) J. Biol. Chem. 269, 20522-20527
14. O'Brien, L. M., Medved, L. V., and Fay, P. J. (1995) J. Biol. Chem. 270, 27087-27092
15. Fay, P. J., and Koshibu, K. (1998) J. Biol. Chem. 273, 19049-19054
16. Fay, P. J., Haidaris, P. J., and Huggins, C. F. (1993) J. Biol. Chem. 268, 17861-17866
17. Lapan, K. A., and Fay, P. J. (1997) J. Biol. Chem. 272, 2082-2088
18. Casillas, G., Simonetti, C., and Pavloveky, A. (1971) Coagulation 4, 107-111
19. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
20. Lollar, P., Fay, P. J., and Fass, D. N. (1993) Meth. Enzymol. 222, 128-143
21. Mimms, L. T., Zampighi, G., Nozaki, Y., Tanford, C., and Reynolds, J. A. (1981) Biochemistry 20, 833-840
22. Laemmli, U. K. (1970) Nature 227, 680-685
23. Sudhakar, K., and Fay, P. J. (1998) Biochemistry 37, 6874-6882
24. Lamphear, B. J., and Fay, P. J. (1992) Blood 80, 3120-3126
25. O'Brien, D. P., Johnson, D., Byfield, P., and Tuddenham, E. G. (1992) Biochemistry 31, 2805-2812
26. Lollar, P., and Parker, C. G. (1990) J. Biol. Chem. 265, 1688-1692
27. O'Brien, L. M., Huggins, C. F., and Fay, P. J. (1997) Blood 90, 3943-3950
28. Sudhakar, K., and Fay, P. J. (1996) J. Biol. Chem. 271, 23015-23021
29. Regan, L. M., O'Brien, L. M., Beattie, T. L., Sudhakar, K., Walker, F. J., and Fay, P. J. (1996) J. Biol. Chem. 271, 3982-3987
30. Donath, M. J. S. H., Lenting, P. J., van Mourik, J. A., and Mertens, K. (1995) J. Biol. Chem. 270, 3648-3655
31. Regan, L. M., and Fay, P. J. (1995) J. Biol. Chem. 270, 8546-8552
32. Foster, P. A., Fulcher, C. A., Houghten, R. A., and Zimmerman, T. S. (1990) Blood 75, 1999-2004