The combination of angiogenesis and blood vessel invasion as a prognostic indicator in primary breast cancer

British Journal of Cancer

Volumn 88, Issue 12, 2003, Pages 1900-1908

  Kato, T ^a,b   Kameoka, S ^a   Kimura, T ^a   Nishikawa, T ^a   Kobayashi, M ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b Onuma Hospital   (Japan)

Author keywords

Angiogenesis; Blood vessel invasion; Breast cancer; Haematogenous dissemination; Long term survival; Microvessel density

Indexed keywords

CYCLINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FLUOROURACIL; MITOMYCIN C; ONCOPROTEIN; PROTEIN P53; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ADOLESCENT; ADULT; AGED; ANGIOGENESIS; ANTIGEN DETECTION; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER GRADING; CANCER INVASION; CANCER SURVIVAL; CELL PROLIFERATION; CYTOKINE RELEASE; DIAGNOSTIC ACCURACY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE; MAJOR CLINICAL STUDY; METASTASIS POTENTIAL; MICROVASCULATURE; MITOSIS INDEX; ONCOGENE C ERB; ONCOGENE NEU; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; QUANTITATIVE DIAGNOSIS; RELAPSE; RELIABILITY; STAINING; STATISTICAL ANALYSIS; TUMOR NECROSIS; TUMOR VOLUME;

ADOLESCENT; ADULT; BLOOD VESSELS; BREAST NEOPLASMS; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM CIRCULATING CELLS; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; PROGNOSIS;

EID: 0037560493     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600921     Document Type: Article

References (47)

1. Arriagada R, Rutqvist LE, Mattsson A et al (1995) Adequate locoregional treatment for early breast cancer may prevent secondary dissemination. J Clin Oncol 13: 2869-2878
2. Baak JPA, van Dop H, Kurver HJ, Hermans JO (1985) The value of morphometry to classic prognosticators in breast cancer. Cancer 56: 374-382
3. Beenken SW, Grizzle WE, Crowe DR et al (2001) Molecular biomarkers for breast cancer prognosis: coexpression of c-erbB-2 and p53. Ann Surg 233: 630-638
4. Bloom HIJ, Richardson WW (1957) Histologic grading and prognosis. Br J Cancer 11: 359-377
5. Braun S, Pantel K, Muller P, Janni W, Hepp F, Kentenich CRM, Gastroph S, Wischnik A, Dimpfl T, Kindermann G, Riethmuller G, Schlimok G (2000) Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer. N Engl J Med 342: 525-533
6. Clemente CG, Boracchi P, Andreola S, Del Vecchio M, Veronesi P, Rilke FO (1992) Peritumoural lymphatic invasion in patients with node-negative mammary duct carcinoma. Cancer 69: 1396-1403
7. Cooperative Breast Cancer Group (1978) Identification of breast cancer patients with high risk of early reccurence after radical mastectomy. II. Clinical and pathological correlations. Cancer 42: 2809-2826
8. Cox DR (1972) Regression models and life tables. J Roy Stat Soc B 34: 187-202
9. Fisher ER, Costantino J, Fisher B, Redmond C, Collaborating national surgical adjuvant breast bowel project investigators (1993) Pathologic findings from the national surgical adjuvant breast project (protocol 4) Discriminants for 15-year survival. Cancer 71: 2141-2150
10. Fisher B, Fisher ER (1966) The inter-relationship of hematogenous and lymphatic tumour cell dissemination. Surg Gynecol Obstet 122: 791-798
11. Fisher B, Wolmark N, Redmond C, Deutsch M, Fisher ER (1981) Findings from NSABP protocol No. B-04: comparison of radical mastectomy with alternative treatments. II. The clinical and biologic significance of medial-central breast cancers. Cancer 48: 1863-1872
12. Fox SB, Leek RD, Bliss J, Mansi JL, Gusterson B, Gatter KC, Harris AL (1997) Association of tumour angiogenesis with bone marrow micrometastases in breast cancer patients. J Natl Cancer Inst 89: 1044-1049
13. Fox SB, Leek RD, Smith K, Hollyer J, Greenall M, Harris AL (1994) Tumor angiogenesis in node-negative breast carcinomas-relationship with epidermal growth factor receptor, estrogen receptor, and survival. Breast Cancer Res Treat 29: 109-116
14. Friedell GH, Betts A, Sommers SC (1965) The prognostic value of blood vessel invasion and lymphocytic infiltrates in breast carcinoma. Cancer 18: 164-166
15. Gasparini G, Weidner N, Bevilacqua P, Maluta S, Palma PD, Caffo O, Barbareschi M, Boracchi P, Marubini E, Pozza F (1994) Tumour microvessel density, p53 expression, tumour size, and peritumoural lymphatic vessel invasion are relevant prognostic markers in node-negative breast carcinoma. J Clin Oncol 12: 454-466
16. Gilchrist KW, Gray R, Fowble B, Tormey DC, Taylor IV (1993) Tumour necrosis is a prognostic predictor for early recurrence and death in lymph-node positive breast cancer: a 10-year follow-up study of 729 Eastern Cooperative Oncology Group patients. J Clin Oncol 11: 1925-1935
17. Gould VE, Linnoila RL, Memoli VA, Warren WH (1983) Neuroendocrine components of the bronchopulmonary tract: hyperplasis, dysplasias, and neoplasms. Lab Invest 49: 519-537
18. Goulding H, Rashid NFNA, Robertson JF, Bell JA, Elston CW, Blamey RW, Ellis IO (1995) Assessment of angiogenesis in breast carcinoma: an important factor in prognosis? Hum Pathol 26: 1196-1200
19. Harbeck N, Untch M, Pachet I, Eiermann W (1994) Tumour cell detection in the bone marrow of breast cancer patients at primary therapy: results of 3-year median follow-up. Br J Cancer 69: 566-571
20. Heimann R, Ferguson D, Powers C, Recant WM, Weichselbaum RR, Hellman S (1996) Angiogenesis as a predictor of long-term survival for patients with node-negative breast cancer. J Natl Cancer Inst 88: 1764-1769
21. Hellman S, Harris J (1987) The appropriate breast carcinoma paradigm. Cancer Res 47: 339-342
22. Horak ER, Leek R, Klenk N, Lejeune S, Smith K, Stuart N, Greenall M, Stepniewska K, Harris AL (1992) Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer. Lancet 340: 1120-1124
23. Kaplan EL, Meier P (1958) Non-parametric estimation from incomplete observations. J Am. Stat Assoc 53: 457-481
24. Kato T, Kameoka S, Kimura T, Nishikawa T, Kobayashi M (2002) Blood vessel invasion as a predictor of long-term survival for Japanese patients with breast cancer. Breast Cancer Res Treat 73: 1-12
25. Kato T, Kameoka S, Kimura T, Soga N, Abe Y, Nishikawa T, Kobayashi M (2001) Angiogenesis as a predictor of long-term survival for 377 Japanese patients with breast cancer. Breast Cancer Res Treat 70: 65-74
26. Kato T, Kimura T, Miyakawa R, Fujii A, Yamamoto K, Kameoka S, Nishikawa T, Kasajima T (2000) Clinicopathological study associated with long-term survival in Japanese patients with node-negative breast cancer. Br J Cancer 82: 404-411
27. Kato T, Kimura T, Miyakawa R, Nobue I, Fujii A, Yamamoto K, Kameoka S, Toshio N, Kasajima T (1999) The methodology of quantitation of microvessel density and prognostic value of neovascularization associated with long-term survival in Japanese patients with breast cancer. Breast Cancer Res Treat 53: 19-31
28. Kato T, Kimura T, Miyakawa R, Tanaka S, Fujii A, Yamamoto K, Kameoka S, Hamano K, Kawakami M, Aiba M (1997) Clinicopathologic study of angiogenesis in Japanese patients with breast cancer. World J Surg 21: 49-56
29. Kister SJ, Sommers SC, Haagensen CD, Cooley E (1996) Reevaluation of blood vessel invasion as a prognostic factor in carcinoma of the breast. Cancer 19: 1213-1216
30. Lauria R, Perrone F, Carlomagna C, De Laurentis M, Morabit A, Gallo C, Varriale E, Pettinato G, Panico L, Petrella G, Bianco AR, De Placido S (1996) The prognostic value of lymphatic and blood vessel invasion in operable breast cancer. Cancer 76: 1772-1778
31. Lee AKC, Delellis RA, Silverman ML, Heatley GJ, Wolfe HJ (1990) Prognostic significance of peritumoural lymphatic and blood vessel Invasion in node-negative carcinoma of the breast. J Clin Oncol 18: 1457-1465
32. Mansi JL, Easton D, Berger U, Gazet J-C, Ford HT, Dearnaley D, Coombes RC (1991) Bone marrow micrometastasis in primary breast cancer: prognostic significance after 6 years' follow-up. Eur J Cancer 27: 1552-1555
33. Mantel N (1966) Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep 50: 163-170
34. Martin SA, Perez-Reyes N, Mendelsonhn G (1987) Angiogenesis in breast carcinoma: an immunohistochemical study of factor VIII-related antigen. Cancer 59: 1918-1922
35. Menard S, Bufalino R, Rilke F, Cascinelli N, Veronesi U, Colnaghi MI (1994) Prognosis based on primary breast carcinoma instead of pathological nodal status. Br J Cancer 70: 709-712
36. Sampat MB, Sirsat MV, Gangadharan P (1977) Prognostic significance of blood vessel invasion in carcinoma of the breast in women. J Surg Oncol 9: 623-632
37. Simpson JF, Ahn C, Battifora H, Esteban JM (1996) Endothelial area as a prognostic indicator for invasive breast carcinoma. Cancer 77: 2077-2085
38. Sirvent JJ, Fortuno-Mar A, Olona M, Orti A (2001) Prognostic value of p53 protein expression and clinicopathological factors in infiltrating ductal carcinoma of the breast. A study of 192 patients. Histol Histopathol 16: 99-106
39. Ted P, Sommers SC (1964) Vascular invasion as a prognostic factor in breast carcinoma. Surg Gynecol Obstet 118: 1006-1008
40. Thor AD, Moore II DH, Edgerton SM, Kawasaki ES, Reihsaus E, Lynch HT, Marcus JN, Schwartz L, Chen LC, Mayall BH, Smith HS (1992) Accumulation of p53 tumour suppressor gene protein: an independent marker of prognosis in breast cancers. J Natl Cancer Inst 84: 1845-1855
41. van de Velde CJH, Gallager HS, Giacco GG (1986) Prognosis in node-negative breast cancer. Breast Cancer Res Treat 8: 189-196
42. Van Hoef MEHM, Knox WF, Dhesi SS, Howell A, Schor AM (1993) Assessment of tumour vascularity as a prognostic factor in lymph node-negative invasive breast cancer. Eur J Cancer 29: 1141-1145
43. Weidner N, Semple JP, Welch WR, Folkman J (1991) Tumour angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 324: 1-8
44. Weigand RA, Isenberg WM, Russo J, Brennan MJ, Rich MA (1982) Blood vessel invasion and axillary lymph-node involvement as prognostic indicators for human breast cancer. Cancer 50: 962-969
45. Wright C, Angus B, Nicholson S, Sainsbury JRC, Cairns J, Gullick WJ, Kelly P, Harris AL, Horne CHW (1989) Expression c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer. Cancer Res 49: 2087-2090
46. Wyllie AH, Beattie GJ, Hargreaves AD (1981) Chromatin changes in apoptosis. Histochem J 13: 681-692
47. Zhang GJ, Kimijima I, Abe R, Watanabe T, Kanno M, Hara K, Tsuchiya A (1998) Apoptotic index correlates to bcl-2 and p53 protein expression, histological grade and prognosis in invasive breast cancers. Anticancer Res 18: 1989-1998