Hyperplastic-like polyps as precursors of microsatellite-unstable colorectal cancer

American Journal of Clinical Pathology

Volumn 119, Issue 6, 2003, Pages 773-775

  Jass, Jeremy R ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MUCIN; SIALIC ACID; MICROSATELLITE DNA;

ADENOMA; CANCER CYTODIAGNOSIS; CELL STRUCTURE; CELL TRANSFORMATION; COLON POLYP; COLORECTAL CANCER; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; DNA METHYLATION; DNA REPAIR; DYSPLASIA; EDITORIAL; GENE CONTROL; GENE EXPRESSION; GENE SEQUENCE; HYPERPLASIA; MICROSATELLITE INSTABILITY; PATHOLOGICAL ANATOMY; PRIORITY JOURNAL; RECTUM POLYP; SIGMOID; UPREGULATION; COLORECTAL TUMOR; GENETICS; HUMAN; NOTE; PATHOLOGY;

COLONIC POLYPS; COLORECTAL NEOPLASMS; DIAGNOSIS, DIFFERENTIAL; HUMANS; MICROSATELLITE REPEATS;

EID: 0037534007     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/UYN70N9W2DVN9ART     Document Type: Editorial

References (14)

1. Goldstein NS, Bhanot P, Odish E, et al. Hyperplastic-like colon polyps that preceded microsatellite-unstable adenocarcinomas. Am J Clin Pathol. 2003;119:778-796.
2. Jass JR, Filipe MI, Abbas S, et al. A morphologic and histochemical study of metaplastic polyps of the colorectum. Cancer. 1984;53:510-515.
3. Torlakovic E, Snover DC. Serrated adenomatous polyposis in humans. Gastroenterology. 1996;110:748-755.
4. Torlakovic E, Skovlund E, Snover DC, et al. Morphologic reappraisal of serrated colorectal polyps. Am J Surg Pathol. 2003;27:65-81.
5. Jass JR, Iino H, Ruszkiewicz A, et al. Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum. Gut. 2000;47:43-49.
6. Jass JR, Young J, Leggett BA. Hyperplastic polyps and DNA microsatellite unstable cancers of the colorectum. Histopathology. 2000;37:295-301.
7. Whitehall VLJ, Walsh MD, Young J, et al. Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability. Cancer Res. 2001;61:827-830.
8. Jass JR, Young PJ, Robinson EM. Predictors of presence, multiplicity, size and dysplasia of colorectal adenomas: a necropsy study in New Zealand. Gut. 1992;33:1508-1514.
9. Hawkins NJ, Ward RL. Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas. J Natl Cancer Inst. 2001;93:1307-1313.
10. Biemer-Hüttmann A-E, Walsh MD, McGuckin MA, et al. Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis. Clin Cancer Res. 2000;6:1909-1916.
11. Whitehall VLJ, Wynter CVA, Walsh MD, et al. Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancer. Cancer Res. 2002;62:6011-6014.
12. Ricciardiello L, Goel A, Mantovani V, et al. Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer. Cancer Res. 2003;63:787-792.
13. Park S-J, Rashid A, Lee J-H, et al. Frequent CpG island methylation in serrated adenomas of the colorectum. Am J Pathol. 2003;162:815-822.
14. Sawyer EJ, Cerar A, Hanby AM, et al. Molecular characteristics of serrated adenomas. Gut. 2002;51:200-206.