Antileukinate, a hexapeptide inhibitor of CXC-chemokine receptor, suppresses bleomycin-induced acute lung injury in mice

Lung

Volumn 180, Issue 6, 2002, Pages 339-348

  Hayashi, S ^a   Yatsunami, J ^a   Fukuno, Y ^a   Kawashima, M ^a   Miller, E J ^b  

^a SAGA UNIVERSITY   (Japan)

^b NORTH SHORE UNIVERSITY HOSPITAL   (United States)

Author keywords

Acute lung injury; Bleomycin; CXC chemokine; Receptor inhibitor

Indexed keywords

ACETYLARGINYLARGINYLTRYTOPHYLTRYPTOPHYLCYSTEINYLARGININAMIDE; ANTILEUKINATE; BLEOMYCIN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXC; HEXAPEPTIDE; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; ALPHA CHEMOKINE; OLIGOPEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HISTOPATHOLOGY; IN VIVO STUDY; LUNG EDEMA; LUNG INJURY; LUNG LAVAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DRUG ANTAGONISM; INSTITUTE FOR CANCER RESEARCH MOUSE;

ANIMALS; BLEOMYCIN; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOKINES, CXC; MALE; MICE; MICE, INBRED ICR; NEUTROPHILS; OLIGOPEPTIDES; RECEPTORS, CHEMOKINE; RESPIRATORY DISTRESS SYNDROME, ADULT;

EID: 0037528969     PISSN: 03412040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00408-002-0106-7     Document Type: Article

References (23)

1. Azuma A, Furuta T, Enomoto T, Hashimoto Y, Uematsu K, Nukariya N, Murata A, Kudoh S (1998) Preventive effect of erythromycin on experimental bleomycin-induced acute lung injury in rats. Thorax 53:186-189
2. Desaki M, Takizawa H, Ohtoshi T, Kasama T, Kobayashi K, Sunazuka T, Omura S, Yamamoto K, Ito K (2000) Erythromycin suppresses nuclear factor-kappaB and activator protein-1 activation in human bronchial epithelial cells. Biochem Biophys Res Commun 267:124-128
3. Dunstan CA, Salafranca MN, Adhikari S, Xia Y, Feng L, Harrison JK (1996) Identification of two rat genes orthologous to the human interleukin-8 receptors. J Biol Chem 271:32770-32776
4. Folkesson HG, Matthay MA, Hebert CA, Broaddus VC (1995) Acid aspiration-induced lung injury in rabbits is mediated by interleukin-8-dependent mechanisms. J Clin Invest 96:107-116
5. Frevert CW, Huang S, Danaee H, Paulauskis JD, Kobzik L (1995) Functional characterization of the rat chemokine KC and its importance in neutrophil recruitment in a rat model of pulmonary inflammation. J Immunol 154:335-344
6. Fujisawa N, Hayashi S, Miller EJ (1999) A synthetic peptide inhibitor for alpha-chemokines inhibits the tumour growth and pulmonary metastasis of human melanoma cells in nude mice. Melanoma Res 9:105-114
7. Hagimoto N, Kuwano K, Nomoto Y, Kunitake R, Hara N (1997) Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice. Am J Respir Cell Mol Biol 16:91-101
8. Hayashi S, Kurdowska A, Miller EJ, Albright ME, Girten BE, Cohen AB (1995) Synthetic hexa- and heptapeptides that inhibit IL-8 from binding to and activating human blood neutrophils. J Immunol 154:814-824
9. Hayashi S, Kurdowska A, Cohen AB, Stevens MD, Fujisawa N, Miller EJ (1997) A synthetic peptide inhibitor for alpha-chemokines inhibits the growth of melanoma cell lines. J Clin Invest 99:2581-2587
10. Ichiyama T, Nishikawa M, Yoshitomi T, Hasegawa S, Matsubara T, Hayashi T, Furukawa S (2001) Clarithromycin inhibits NF-kappaB activation in human peripheral blood mononuclear cells and pulmonary epithelial cells. Antimicrob Agents Chemother 45:44-47
11. Jerva LF, Sullivan G, Lolis E (1997) Functional and receptor binding characterization of recombinant murine macrophage inflammatory protein 2: sequence analysis and mutagenesis identify receptor binding epitopes. Protein Sci 6:1643-1652
12. Kawashima M, Yatsunami J, Fukuno Y, Nagata M, Tominaga M, Hayashi S (2002) Inhibitory effects of 14-membered ring macrolide antibiotics on bleomycin-induced acute lung injury. Lung 180:73-89
13. Lee J, Kuang WJ, Rice GC, Wood WI (1992) Characterization of complementary DNA clones encoding the rabbit IL-8 receptor. J Immunol 148:1261-1264
14. Loetscher P, Seitz M, Clark-Lewis I, Baggiolini M, Moser B (1994) Both interleukin-8 receptors independently mediate chemotaxis. Jurkat cells transfected with IL-8R1 or IL-8R2 migrate in response to IL-8, GRO alpha and NAP-2. FEBS Lett 341:187-192
15. Matthay MA, Uchida T, Fang X (2002) Clinical acute lung injury and acute respiratory distress syndrome. Curr Treatment Options Cardiovasc Med 4:139-149
16. Meade MO, Herridge MS (2001) An evidence-based approach to acute respiratory distress syndrome. Respir Care 46:1368-1376
17. Miller EJ, Cohen AB, Nagao S, Griffith D, Maunder RJ, Martin TR, Weiner-Kronish JP, Sticherling M, Christophers E, Matthay MA (1992) Elevated levels of NAP-1/interleukin-8 are present in the airspaces of patients with the adult respiratory distress syndrome and are associated with increased mortality. Am Rev Respir Dis 146:427-432
18. Mitsuhashi H, Asano S, Nonaka T, Hamamura I, Masuda K, Kiyoki M (1996) Administration of truncated secretory leukoprotease inhibitor ameliorates bleomycin-induced pulmonary fibrosis in hamsters. Am J Respir Crit Care Med 153:369-374
19. Nagai A, Aoshiba K, Ishihara Y, Inano H, Sakamoto K, Yamaguchi E, Kagawa J, Takizawa T (1992) Administration of alpha 1-proteinase inhibitor ameliorates bleomycin-induced pulmonary fibrosis in hamsters. Am Rev Respir Dis 145:651-656
20. Nakamura M, Fujishima S, Sawafuji M, Ishizaka A, Oguma T, Soejima K, Matsubara H, Tasaka S, Kikuchi K, Kobayashi K, Ikeda E, Sadick M, Hebert CA, Aikawa N, Kanazawa M, Yamaguchi K (2000) Importance of interleukin-8 in the development of reexpansion lung injury in rabbits. Am J Respir Crit Care Med 161:1030-1036
21. Sato E, Koyama S, Masubuchi T, Takamizawa A, Kubo K, Nagai S, Izumi T (1999) Bleomycin stimulates lung epithelial cells to release neutrophil and monocyte chemotactic activities. Am J Physiol 276:L941-950
22. Strieter RM, Kunkel SL, Keane MP, Standiford TJ (1999) Chemokines in lung injury: Thomas A. Neff Lecture. Chest 116:103S-110S
23. Takamizawa A, Koyama S, Sato E, Masubuchi T, Kubo K, Sekiguchi M, Nagai S, Izumi T (1999) Bleomycin stimulates lung fibroblasts to release neutrophil and monocyte chemotactic activity. J Immunol 162:6200-6208