High frequency of hepatitis B virus infection in patients with β-thalassemia receiving multiple transfusions

Vox Sanguinis

Volumn 84, Issue 4, 2003, Pages 292-299

  Singh, H ^a   Pradhan, M ^b   Singh, R L ^b   Phadke, S ^a   Naik, Sita R ^a   Aggarwal, R ^a   Naik, S ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^b DR RAM MANOHAR LOHIA AVADH UNIVERSITY   (India)

Author keywords

thalassemia; Anti HBs response; HBV vaccine; S gene mutant

Indexed keywords

EPITOPE; HEPATITIS B CORE ANTIBODY; HEPATITIS B SURFACE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; RECOMBINANT HEPATITIS B VACCINE; VIRUS DNA;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIBODY TITER; ARTICLE; BETA THALASSEMIA; BLOOD TRANSFUSION; CHILD; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DISEASE TRANSMISSION; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE MUTATION; GENOTYPE; HEPATITIS B; HUMAN; HYDROPHOBICITY; INFANT; MAJOR CLINICAL STUDY; MALE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; S GENE; SEROLOGY; SOUTHERN BLOTTING; STRUCTURAL GENE; TORQUE TENO VIRUS; VACCINATION; VIRUS CELL INTERACTION; VIRUS GENE; VIRUS LOAD; VIRUS STRAIN;

ADOLESCENT; ADULT; BASE SEQUENCE; BETA-THALASSEMIA; BLOOD TRANSFUSION; CHILD; CHILD, PRESCHOOL; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HUMANS; INDIA; INFANT; MALE; MUTATION, MISSENSE; POINT MUTATION; PREVALENCE; VIRAL PROTEINS;

EID: 0037528891     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1423-0410.2003.00300.x     Document Type: Article

References (37)

1. Regan FA, Hewitt P, Barbara JA, Contreras M: Prospective investigation of transfusion transmitted infection in recipients of over 20 000 units of blood. TTI Study Group, BMJ 2000; 320:403-406
2. Wang TH, Wang JT, Lin JT, Shen JC, Sung JL, Chen DS: A prospective study of post transfusion hepatitis in Taiwan. J Hepatol 1991; 13:38-43
3. Thygarajan SP, Jayaram S, Mohanavalli B: Prevalence of HBV in general population of India; in Sarin SK, Singal AK (eds): Hepatitis B in India: Problems and Prevention. New Delhi, CBS Publishers and Distributors, 1996:5-16
4. Lai ME, Farci P, Figus A, Balestrieri A, Amone M, Vyas GN: Hepatitis B virus DNA in the serum of Sardinian blood donors negative for the hepatitis B surface antigen. Blood 1989; 73:17-19
5. Nagaraju K, Mishra S, Saraswat S, Choudhary N, Masih B, Ramesh V, Naik S: High prevalence of HBV infectivity in blood donors detected by dot-blot hybridization assay. Vox Sang 1994; 67:117-124
6. Theirs V, Nakajima E, Kremsdorf D, Mack D, Schellekens H, Driss F, Goudeau A, Wands J, Sninsky J, Tiollais P, Brechot C: Transmission of hepatitis B from hepatitis sero-negative patients. Lancet 1988; 2:1273-1276
7. Saraswat S, Banerjee K, Chaudhary N, Mahant TS, Khandekar PS, Gupta RK, Naik S: Post transfusion hepatitis B following multiple transfusion of HBsAg negative blood. J Hepatol 1996; 67:237-239
8. Sukumaran PK, Master HR: The distribution of abnormal hemoglobin in the Indian population. Proc First Conf Indian Soc Human Genetics 1974; 1:91
9. Cacopardo B, Russo R, Fatuzzo R, Cosentino S, Lombardo T, La Rosa Celesia BM, Nigro L, Frontini V, Nunnari A: HCV and HBV infection among multitransfused thalassemics from Eastern Sicily. Infection 1992; 202:83-85
10. Kocabas E, Aksaray N, Alban E, Yarkin F, Koksal F, Kilinc Y: Hepatitis B and C virus infection in Turkish children with hemophilia. Acta Paediatr 1997; 86:1135-1137
11. Amarapurkar DN, Kumar A, Vaiday S, Murti P, Bichile SK, Kalro RH, Desai HG: Frequency of hepatitis B, C and D and human immunodeficiency virus infections in multi-transfused thalassemics. Indian J Gastroenterol 1992; 11:80-81
12. Gulati S, Marwaha RK, Dilawari JB, Midha U, Walia BNS: Serological responses to hepatitis B virus infection in multi-transfused thalassemic children. Indian Pediatr 1991; 29:73-77
13. Carman WF, Zanetti AR, Karayiannis P, Waters J, Manzillo G, Tanzi E, Zuckerman AJ, Thomas HC: Vaccine-induced escape mutant of hepatitis B virus. Lancet 1990; 336:325-329
14. Okamoto H, Yano K, Nozaki Y, Matsui A, Miyazaki H, Yamamoto K, Tsuda F, Machida A, Mishiro S: Mutations within the S gene of hepatitis B virus transmitted from mothers to babies immunized with hepatitis B immune globulin and vaccine. Pediatr Res 1992; 32:264-268
15. Oon CJ, Lim GK, Ye Z, Goh KT, Tan KL, Yo SL, Hopes E, Harrison TJ, Zuckerman AJ: Molecular epidemiology of hepatitis B virus vaccine variants in Singapore. Vaccine 1995; 13:699-702
16. Carman WF, Korula J, Wallace L, MacPhee R, Mimms L, Decker R: Fulminant reactivation of hepatitis B due to envelope protein mutant that escaped detection by monoclonal HBsAg ELISA. Lancet 1995; 345:1406-1407
17. Kalinina T, Riu A, Fischer L, Will H, Sterneck M: A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis. Hepatology 2001; 34:385-394
18. Keller GH, Cumming CU, Huang DP, Manak MM, Ting R: A chemical method for introducing haptens onto DNA probes. Anal Biochem 1988; 170:441-450
19. Nayersina R, Fowler P, Guilhot S, Missale G, Cerny A, Schlicht H-J, Vitiello A, Chesnut R, Person JL, Redeker AG, Chisari FV: HLA A2 restricted cytotoxic T lymphocyte responses to multiple hepatitis B surface antigen epitopes during hepatitis B virus infection. J Immunol 1993; 150:4659-4671
20. Boni C, Penna A, Ogg GS, Bertoletti A, Pilli M, Cavallo C, Cavalli A, Urbani S, Boehme R, Panebianco R, Fiaccadori F, Ferrari C: Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: new perspectives for immune therapy. Hepatology 2001; 33:963-971
21. Bairoch A, Gasteiger E, Alexandre G, Hoogland C, Corinne L, Mostaguir K, Ivanyi I, Appel RD: ExPASy Molecular Biology Server. Geneva, Switzerland, Swiss Institute of Bioinformatics, 2002 [Proteomics tools: ProtScale. Cited: March, Available from: URL. http://expasy.ch/cgi-bin/protscale.pl]
22. Kyte J, Doolittle RF: A simple method for displaying the hydropathic character of a protein. J Mol Biol 1982; 157:105-132
23. Ling R, Mutimer D, Ahmed M, Boxall EH, Elias E, Dusheiko GM, Harrison TJ: Selection of mutations in the hepatitis B virus polymerase during therapy of transplant recipients with lamivudine. Hepatology 1996; 24:711-713
24. Aye TT, Bartholomeusz A, Shaw T, Bowden S, Breschkin A, McMillan J, Angus P, Locarnini S: Hepatitis B virus polymerase mutations during anti-viral therapy in a patient following liver transplantation. J Hepatol 1997; 26:1148-1153
25. Gerety RJ, Aronson DC: Plasma derivatives and viral hepatitis. Transfusion 1982; 22:347-351
26. Omara FO, Blakley BR: The effects of iron deficiency and iron overload on cell-mediated immunity in the mouse. Br J Nutr 1994; 72:899-909
27. Terrault NA, Zhou S, McCory RW, Pruett TL, Lake JR, Roberts JP, Ascher NL, Wright TL: Incidence and clinical consequences of surface and polymerase gene mutations in liver transplant recipients on hepatitis B immunoglobulin. Hepatology 1998; 28:555-561
28. Kohno H, Inoue T, Tsuda F, Okamoto H, Akahane Y: Mutations in the envelope gene of hepatitis B virus variants co-occurring with antibody to surface antigen in sera from patients with chronic hepatitis B. J Gen Virol 1996; 77:1825-1831
29. Bruss V, Ganem D: Mutational analysis of hepatitis B surface antigen particle assembly and secretion. J Virol 1991; 65:3813-3820
30. Mangold CM, Streeck RE: Mutational analysis of the cysteine residues in the hepatitis B virus small envelope protein. J Virol 1993; 67:4588-4597
31. Ellgaard L, Molinari M, Helenius A: Setting the standards: quality control in the secretory pathway. Science 1999; 341: 349-353
32. Wang XZ, Lawson B, Brewer JW, Sinszner H, Sanjay A, Mi LJ, Boorstein R, Kreibich G, Hendershot LM, Ron D: Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). Mol Cell Biol 1996; 16:4273-4280
33. Ogura Y, Kurosaki M, Asahina Y, Enomoto N, Marumo F, Sato C: Prevalence and significance of naturally occurring mutations in the surface and polymerase genes of hepatitis B virus. J Infect Dis 1999; 180:1444-1451
34. Bertoletti A, Sette A, Chisari FV, Penna A, Levreno M, De Carli M, Fiaccadori F, Ferrari C: Natural variants of cytotoxic epitopes and T-cell receptor antagonists for anti-viral cytotoxic T cells. Nature 1994; 369:407-410
35. Oon CJ, Chen WN, Lim N, Koh S, Lim GK, Leong AL, Tan GS: Hepatitis B virus variants with lamivudine-related mutations in the DNA polymerase and the 'a' epitope of the surface antigen are sensitive to ganciclovir. Antiviral Res 1999; 41:113-118
36. Bock CT, Tillmann HL, Torresi J, Klempnauer J, Locamini S, Manns MP, Trautwein C: Selection of hepatitis B virus polymerase mutants with enhanced replication by lamivudine treatment after liver transplantation. Gastroenterology 2002; 122:264-273
37. Stuyver LJ, Locamini SA, Lok A, Richman DD, Carman WF, Dienstag JL, Schinazi RF: Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region. Hepatology 2001; 33:751-757