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Volumn 31, Issue 3, 2003, Pages 528-531
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Molecular mechanism for inhibition of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase by rosuvastatin
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Author keywords
Atherosclerosis; Cholesterol lowering; Enzyme inhibition; Isothermal titration calorimetry; Statin; X ray crystallography
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Indexed keywords
ATORVASTATIN;
CERIVASTATIN;
FLUINDOSTATIN;
HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE;
LIPOPROTEIN;
PRAVASTATIN;
ROSUVASTATIN;
SIMVASTATIN;
STATINE;
ATHEROSCLEROSIS;
BINDING AFFINITY;
CLINICAL TRIAL;
CONFERENCE PAPER;
CRYSTAL STRUCTURE;
DRUG BINDING;
DRUG EFFECT;
DRUG MECHANISM;
DRUG METABOLISM;
ENTHALPY;
ENZYME BINDING;
ENZYME INHIBITION;
ENZYME MECHANISM;
HIGH RISK POPULATION;
HUMAN;
INHIBITION KINETICS;
MOLECULAR BIOLOGY;
PRIORITY JOURNAL;
STEADY STATE;
X RAY CRYSTALLOGRAPHY;
FLUOROBENZENES;
HUMANS;
HYDROXYMETHYLGLUTARYL COA REDUCTASES;
HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS;
KINETICS;
PYRIMIDINES;
SULFONAMIDES;
THERMODYNAMICS;
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EID: 0037527704
PISSN: 03005127
EISSN: None
Source Type: Journal
DOI: 10.1042/BST0310528 Document Type: Conference Paper |
Times cited : (86)
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References (13)
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