The Role of T-Lymphocytes in Hypercholesterolemia-Induced Leukocyte-Endothelial Interactions

Microcirculation

Volumn 9, Issue 5, 2002, Pages 407-417

  Stokes, Karen Y ^a   Clanton, E Chris ^a   Bowles, Kimberly S ^a   Fuseler, John W ^a   Chervenak, Deborah ^a   Chervenak, Robert ^a   Jennings, Stephen R ^a   Granger, D Neil ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Hypercholesterolemia; Leukocyte emigration; Microvasculature; T lymphocytes

Indexed keywords

ANIMAL; ARTICLE; CELL ADHESION; CELL COMMUNICATION; CYTOLOGY; GRANULOCYTE; HYPERCHOLESTEROLEMIA; LEUKOCYTE ROLLING; MOUSE; MOUSE MUTANT; MOUSE STRAIN; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PHYSIOLOGY; T LYMPHOCYTE; VASCULAR ENDOTHELIUM; VENULE;

ANIMALS; CELL ADHESION; CELL COMMUNICATION; CHEMOTAXIS, LEUKOCYTE; ENDOTHELIUM, VASCULAR; GRANULOCYTES; HYPERCHOLESTEROLEMIA; LEUKOCYTE ROLLING; MICE; MICE, INBRED STRAINS; MICE, SCID; T-LYMPHOCYTES; VENULES;

ANIMALIA;

EID: 0037510804     PISSN: 10739688     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mn.7800148     Document Type: Article

References (39)

1. Baez S. (1973). An open cremaster muscle preparation for the study of blood vessels by in vivo microscopy. Microvasc Res 5:384-894.
2. Bratt J, Palmblad J. (1997). Cytokine-induced neutrophil-mediated injury of human endothelial cells. J Immunol 159:912-918.
3. Collins RG, Velji R, Guevara NV, Hicks MJ, Chan L, Beaudet AL. (2000). P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E- deficient mice. J Exp Med 191:189-194.
4. d'Uscio LV, Baker TA, Mantilla CB, Smith L, Weiler D. Sieck GC, Katusic ZS. (2001). Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 21:1017-1022.
5. Dansky HM, Charlton SA, Harper MM, Smith JD. (1997). T and B lymphocytes play a minor role in atherosclerotic plaque formation in the apolipoprotein E-deficient mouse. Proc Natl Acad Sci USA 94: 4642-4046.
6. Daugherty A, Pure E, Delfel-Butteiger D, Chen S, Leferovich J, Roselaar SE, Rader DJ. (1997). The effects of total lymphocyte deficiency on the extent of atherosclerosis in apolipoprotein E-/- mice. J Clin Invest 100:1575-1580.
7. de Boer OJ, van der Wal AC, Verhagen CE, Becker AE. (1999). Cytokine secretion profiles of cloned T cells from human aortic atherosclerotic plaques. J Pathol 188:174-179.
8. Emeson EE, Shen ML, Bell CG, Qureshi A. (1996). Inhibition of atherosclerosis in CD4 T-cell-ablated and nude (nu/nu) C57BL/6 hyperlipidemic mice. Am J Pathol 149:675-685.
9. Eriksson EE, Xie X, Werr J, Thoren P, Lindbom L. (2001). Direct viewing of atherosclerosis in vivo: plaque invasion by leukocytes is initiated by the endothelial selectins. Faseb J 15:1149-1157.
10. Frostegard J, Ulfgren AK, Nyberg P, Hedin U, Swedenborg J, Andersson L, Hansson GK. (1999). Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines. Atherosclerosis 145:33-43.
11. Fyfe AI, Qiao JH, Lusis AJ. (1994). Immune-deficient mice develop typical atherosclerotic fatty streaks when fed an atherogenic diet. J Clin Invest 94:2516-2520.
12. Gauthier TW, Scalia R, Murohara T, Guo JP, Lefer AM. (1995). Nitric oxide protects against leukocyte-endothelium interactions in the early stages of hypercholesterolemia. Arterioscler Thromb Vasc Biol 15:1652-1659.
13. Gupta S, Pablo AM, Jiang X, Wang N, Tall AR, Schindler C. (1997). IFN-gamma potentiates atherosclerosis in ApoE knock-out mice. J Clin Invest 99:2752-2761.
14. Hansson GK, Seifert PS, Olsson G, Bondjers G. (1991). Immunohistochemical detection of macrophages and T lymphocytes in atherosclerotic lesions of cholesterol-fed rabbits. Arterioscler Thromb 11:745-750.
15. Hasdai D, Nielsen MF, Rizza RA, Holmes DR Jr., Richardson DM, Cohen P, Lerman A. (1999). Attenuated in vitro coronary arteriolar vasorelaxation to insulin-like growth factor I in experimental hypercholesterolemia. Hypertension 34:89-95.
16. Horie Y, Chervenak RP, Wolf R, Gerritsen ME, Anderson DG, Komatsu S, Granger DN. (1997). Lymphocytes mediate TNF-alpha-induced endothelial cell adhesion molecule expression: studies on SCID and RAG-1 mutant mice. J Immunol 159:5053-5062.
17. Horie Y, Wolf R, Chervenak RP, Jennings SR, Granger DN. (1999). T-lymphocytes contribute to hepatic leukostasis and hypoxic stress induced by gut ischemia-reperfusion. Microcirculation 6:267-280.
18. Huber SA, Sakkinen P, David C, Newell MK, Tracy RP. (2001). T helper-cell phenotype regulates atherosclerosis in mice under conditions of mild hypercholesterolemia. Circulation 103:2610-2616.
19. Iiyama K, Hajra L, Iiyama M, Li H, DiChiara M, Medoff BD, Cybulsky MI. (1999). Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation. Circ Res 85:199-207.
20. Klouche M, May AE, Hemmes M, Messner M, Kanse SM, Preissner KT, Bhakdi S. (1999). Enzymatically modified, nonoxidized LDL induces selective adhesion and transmigration of monocytes and T-lymphocytes through human endothelial cell monolayers. Arterioscler Thromb Vasc Biol 19:784-793.
21. Kokura S, Wolf RE, Yoshikawa T, Granger DN, Aw TY. (2000). Postanoxic T lymphocyte-endothelial cell interactions induce tumor necrosis factor-alpha production and neutrophil adhesion: role of very late antigen-4/vascular cell adhesion molecule-1. Circ Res 86:1237-1244.
22. Manka D, Collins RG, Ley K, Beaudet AL, Sarembock IJ. (2001). Absence of P-selectin, but not intercellular adhesion molecule-1, attenuates neointimal growth after arterial injury in apolipoprotein E-deficient mice. Circulation 103:1000-1005.
23. Misiakos EP, Kouraklis G, Agapitos E, Perrea D, Karatzas G, Boudoulas H, Karayannakos PE. (2001). Expression of PDCF-A, TGFb and VCAM-1 during the developmental stages of experimental atherosclerosis. Eur Surg Res 33:264-269.
24. O'Brien KD, McDonald TO, Chait A, Allen MD, Alpers CE. (1996). Neovascular expression of E-selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in human atherosclerosis and their relation to intimal leukocyte content. Circulation 93:672-682.
25. Reardon CA, Blachowicz L, White T, Cabana V, Wang Y, Lukens J, Bluestone J, Getz GS. (2001). Effect of immune deficiency on lipoproteins and atherosclerosis in male apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 21:1011-1016.
26. Roselaar SE, Kakkanathu PX, Daugherty A. (1996). Lymphocyte populations in atherosclerotic lesions of apoE -/- and EDL receptor -/-mice. Decreasing density with disease progression. Arterioscler Thromb Vasc Biol 16:1013-1018.
27. Sakai A, Kume N, Nishi E, Tanoue K, Miyasaka M, Kita T. (1997). P-selectin and vascular cell adhesion molecule-1 are focally expressed in aortas of hypercholesterolemic rabbits before intimai accumulation of macrophages and T lymphocytes. Arterioscler Thromb Vasc Biol 17:310-316.
28. Scalia R, Appel JZ 3rd, Lefer AM. (1998). Leukocyte-endothelium interaction during the early stages of hypercholesterolemia in the rabbit: role of P-selectin, ICAM-1 and VCAM-1. Arterioscler Thromb Vasc Biol 18:1093-1100.
29. Shigematsu T, Wolf RE, Granger DN. (2002). T-lymphocytes modulate the microvascular and inflammatory responses to intestinal ischemia-reperfusion. Microcirculation 9:99-109.
30. Song E, Leung C, Schindler C. (2001). Lymphocytes are important in early atherosclerosis. J Clin Invest 108:251-259.
31. Stokes K, Russell J, Vallien G, Tailor A, Granger DN. (2000). Hypercholesterolemia alters endothelial cell adhesion molecule expression. FASEB J 14:A274 (abstr.).
32. Stokes KY, Clanton EC, Russell JM, Ross CR, Granger DN. (2001). NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion. Circ Res 88:499-505.
33. Takada M, Nadeau KC, Shaw GD, Marquette KA, Tilney NL. (1997). The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligarid. J Clin Invest 99:2682-2690.
34. Tellides G, Tereb DA, Kirkiles-Smith NC, Kim RW, Wilson JH, Schechner JS, Lorber MI, Pober JS. (2000). Interferon-gamma elicits arteriosclerosis in the absence of leukocytes. Nature 403:207-211.
35. Vink H, Constantinescu AA, Spaan JA. (2000). Oxidized lipoproteins degrade the endothelial surface layer: implications for platelet-endothelial cell adhesion. Circulation 101:1500-1502.
36. + T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice. Circulation 102:2919-2922.
37. Zhou X, Paulsson G, Stemme S, Hansson GK. (1998). Hypercholesterolemia is associated with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice. J Clin Invest 101:1717-1725.
38. Zhou X, Stemme S, Hansson GK. (1996). Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apolipoprotein-E-deficient mice. Am J Pathol 149:359-366.
39. + T-lymphocytes mediate ischemia/reperfusion-induced inflammatory responses in mouse liver. J Clin Invest 100:279-289.