Antisense treatment against Ki-67 mRNA inhibits proliferation and tumor growth in vitro and in vivo

International Journal of Cancer

Volumn 105, Issue 5, 2003, Pages 710-716

  Kausch, Ingo ^a   Lingnau, Anja ^a   Endl, Elmar ^b   Sellmann, Kirsten ^a   Deinert, Irina ^b   Ratliff, Timothy L ^c   Jocham, Dieter ^a   Sczakiel, Georg ^a   Gerdes, Johannes ^b   Böhle, Andreas ^a,b  

^a UNIVERSITY OF LÜBECK   (Germany)

^b RESEARCH CENTER BORSTEL   (Germany)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

Antisense; Cancer; Ki 67; Molecular therapy; Proliferation

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; DNA; KI 67 ANTIGEN; MESSENGER RNA; PHOSPHOROTHIOIC ACID DERIVATIVE;

ANIMAL MODEL; APOPTOSIS; ARTICLE; BLADDER CARCINOMA; CANCER INHIBITION; CANCER THERAPY; CELL DEATH; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DNA CONTENT; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MONOLAYER CULTURE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSMOTIC MINIPUMP; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPHEROID CELL; TRANSITIONAL CELL CARCINOMA; TREATMENT OUTCOME; TUMOR CELL; TUMOR GROWTH;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; BREAST NEOPLASMS; CARCINOMA, TRANSITIONAL CELL; CELL CULTURE TECHNIQUES; CELL DIVISION; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; FIBROBLASTS; GENE THERAPY; HUMANS; KI-67 ANTIGEN; MALE; MICE; MULTIPLE MYELOMA; NEOPLASM PROTEINS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PROSTATIC NEOPLASMS; RNA, MESSENGER; RNA, NEOPLASM; SPHEROIDS, CELLULAR; SUSPENSIONS; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS;

EID: 0037499493     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.11111     Document Type: Article

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