Anti-angiogenic activity of terpestacin, a bicyclo sesterterpene from Embellisia chlamydospora

Journal of Antibiotics

Volumn 56, Issue 5, 2003, Pages 492-496

  Jung, Hye Jing ^a   Lee, Hyang Burm ^b   Kim, Chang Jin ^b   Rho, Jung Rae ^c   Shin, Jongheon ^d   Kwon, Ho Jeong ^a  

^a Sejong University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Korea Research Institute of Ships and Ocean Engineering   (South Korea)

^d Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; SESTERTERPENE; TERPESTACIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; AORTA; CELL VIABILITY; CHORIOALLANTOIS; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; EMBELLISIA CHLAMYDOSPORA; ENDOTHELIUM CELL; IN VITRO STUDY; IN VIVO STUDY; MICROORGANISM; NONHUMAN; NOTE; PRIORITY JOURNAL;

EMBELLISIA CHLAMYDOSPORA;

EID: 0037495960     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.56.492     Document Type: Note

References (18)

1. FOLKMAN, J.: Tumor angiogenesis. Adv. Cancer Res. 43: 175-203, 1985
2. CARMELIET, P. & R. K. JAIN: Angiogenesis in cancer and other diseases. Nature 407: 249-257, 2000
3. ANDRE, T.; E. CHASTRE, L. KOTELEVETS, J. C. VAILLANT, C. LOUVET, J. BALOSSO, E. L. GALL, S. PREVOT & C. GESPACH: Tumoral angiogenesis: physiopathology, prognostic value and therapeutic perspectives. Rev. Med. Interne. 19: 904-913, 1998
4. BATTEGAY, E. J.: Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects. J. Mol. Med. 73: 333-346, 1995
5. CAO, Y.: Endogenous angiogenesis inhibitors and their therapeutic implications. Int. J. Biochem. Cell Biol. 33: 357-369, 2001
6. DAMATO, R.; M. S. LOUGHNAN, E. FLYNN & J. FOLKMAN: Thalidomide is an inhibitor of angiogenesis. Proc. Natl. Acad. Sci. USA 91: 4082-4085, 1994
7. DEPLANQUE, G. & A. L. HARRIS: Anti-angiogenic agents: clinical trial design and therapies in development. Eur. J. Cancer 36: 1713-1724, 2000
8. INGBER, D.; T. FUJITA, S. KISHIMOTO, K. SUDO, T. KANAMARU, H. BREM & J. FOLKMAN: Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumor growth. Nature 348: 555-557, 1990
9. KWON, H. J.; J. S. SHIM, J. H. KIM, H. Y. CHO, Y. N. YUM, S. H. KIM & J. H. YU: Betulinic acid inhibits growth factor-induced in vitro angiogenesis via the modulation of mitochondrial function in endothelial cells. Jpn. J. Cancer Res. 93: 417-425, 2002
10. SHIM, J. S.; D. H. KIM, H. J. JUNG, J. H. KIM, D. Y. LIM, S. K. LEE, K. W. KIM, J. W. AHN, J. S. YOO, J. R. RHO, J. H. SHIN & H. J. KWON: Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation. Bioorg. Med. Chem. 10: 2987-2992, 2002
11. KWON, H. J.; M. S. KIM, M. J. KIM, H. NAKAJIMA & K. W. KIM: Histone deacetylase inhibitor, FK228, inhibits tumor angiogenesis. Int. J. Cancer 97: 290-296, 2002
12. OKA, M.; S. IIMURA, O. TENMYO, Y. SAWADA, M. SUGAWARA, N. OHKUSA, H. YAMAMOTO, K. KAWANO, S. L. HU, Y. FUKAGAWA & T. OKI: Terpestacin, a new syncytium formation inhibitor from Arthrinium sp. J. Antibiotics 46: 367-373, 1993
13. SUGAWARA, F; G. STROBEL, L. E. FISHER, G. D. VAN DUYNE & J. CLARDY: Bipolaroxin, a selective phytotoxin produced by Bipolaris cynodontis. Proc. Natl. Acad. Sci. USA 82: 8291-8294, 1985
14. BUSSOLINO, F.; A. MANTOVANI & G. PERSICO: Molecular mechanisms of blood vessel formation. Trends Biochem. Sci. 22: 251-256, 1997
15. KUWANO, M.; J. FUKUSHI, M. OKAMOTO, A. NISHIE, H. GOTO, T. ISHIBASHI & M. ONO: Angiogenesis factors. Intern. Med. 40: 565-572, 2001
16. KWON, H. J.; M. YOSHIDA, R. NAGAOKA, T. OBINATA, T. BEPPU & S. HORINOUCHI: Suppression of morphological transformation by radicicol is accompanied by enhanced gelsolin expression. Oncogene, 15: 2625-2631, 1997
17. OIKAWA, T.; H. ITO, H. ASHINO, M. TOI, T. TOMINAGA, I. MORITA & S. MUROTA: Radicicol, a microbial cell differentiation modulator, inhibits in vivo angiogenesis. Eur. J. Pharmacol. 241: 221-227, 1993
18. PINTUS, G.; B. TADOLINI, A. M. POSADINO, B. SANNA, M. DEBIDDA, F. BENNARDINI, G. SAVA & C. VENTURA: Inhibition of the MEK/ERK signaling pathway by the novel anti-metastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation. Eur. J. Biochem. 269: 5861-5870, 2002