13C and 15N kinetic isotope effects on the reaction of aspartate aminotransferase and the tyrosine-225 to phenylalanine mutant

Biochemistry

Volumn 39, Issue 25, 2000, Pages 7546-7551

  Rishavy, Mark A ^a   Cleland, W W ^a  

^a UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE; PHENYLALANINE; CARBON; NITROGEN; TYROSINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; HYDROLYSIS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; REACTION ANALYSIS; SWINE; AMINO ACID SUBSTITUTION; CHEMISTRY;

ANIMALIA; ESCHERICHIA COLI; SUIDAE; SUS SCROFA;

AMINO ACID SUBSTITUTION; ASPARTATE AMINOTRANSFERASES; CARBON ISOTOPES; NITROGEN ISOTOPES; PHENYLALANINE; TYROSINE;

EID: 0034720690     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi000458d     Document Type: Article

References (30)

1. Meister, A., Sober, H., and Peterson, E. A. (1954) J. Biol. Chem. 206, 89-100.
2. Jenkins, W. T., Yphantis, D. A., and Sizer, I. W. (1959) J. Biol. Chem. 234, 51-57.
3. Velick, S. F., and Vavra, J. (1962) J. Biol. Chem. 262, 2109-2122.
4. Christen, P., and Metzler, D. E., Eds. (1985) Transaminases, John Wiley & Sons, New York.
5. Braunstein, A. E. (1973) in The Enzymes (Boyer, P. D., Ed.) pp 379-481, Academic Press, New York.
6. Kirsch, J. F., Eichele, G., Ford, G. C., Vincent, M. G., Jansonius, J. N., Gehring, H., and Christen, P. (1984) J. Mol. Biol. 174, 497-525.
7. Toney, M. D., and Kirsch, J. F. (1989) Science 243, 1485-1487.
8. McLeish, M. J., Julin, D. A., and Kirsch, J. F. (1989) Biochemistry 28, 3821-3825.
9. Ziak, M., Jaussi, R., Gehring, H., and Christen, P. (1990) Eur. J. Biochem. 187, 329-333.
10. Planas, A., and Kirsch, J. F. (1991) Biochemistry 30, 8268-8276.
11. Toney, M. D., and Kirsch, J. F. (1993) Biochemistry 32, 1471-1479.
12. Goldberg, J. M., Swanson, R. V., Goodman, H. S., and Kirsch, J. F. (1991) Biochemistry 30, 305-312.
13. Inoue, K., Kuramitsu, S., Okamoto, A., Hirutsu, K., Higachi, T. Morino, Y. and Kagamiyama, H. (1991) J. Biochem. (Tokyo) 109, 570-576.
14. Goldberg, J. M., and Kirsch, J. F. (1996) Biochemistry 35, 5280-5291.
15. Birolo, L., Sandmeier, E., Christen, P., and John, R. A. (1995) Eur. J. Biochem. 232, 859-864.
16. Kirsch, J. F., Toney, M. D., and Goldberg, J. M. (1990) in Protein and Pharmaceutical Engineering (Craik, C. S., Fletterick, R., Matthews, C. R., and Wells, J., Eds.) pp 105-118, Wiley-Liss, New York.
17. Julin, D. A., and Kirsch, J. F. (1989) Biochemistry 28, 3825-3833.
18. Gloss, L. M., Planas, A., and Kirsch, J. F. (1992) Biochemistry 31, 32-39.
19. Smith, D. L., Almo, S. C., Toney, M. D., and Ringe, D. (1989) Biochemistry 28, 8161-8167.
20. Edens, W. A., Urbauer, J. L., and Cleland, W. W. (1997) Biochemistry 36, 1141-1147.
21. Cleland, W. W. (1979) Methods Enzymol. 63, 103-138.
22. Fasella, P., Giartosio, A., and Hammes, G. G. (1966) Biochemistry 5, 197-202.
23. Kiick, D. M., and Cook, P. F. (1983) Biochemistry 22, 375-382.
24. Kochar, S., Finlayson, W. L., Kirsch, J. F., and Christen, P. (1987) J. Biol. Chem. 262, 11446-11448.
25. Toney, M. D., and Kirsch, J. F. (1987) J. Biol. Chem. 262, 12403-12405.
26. Rishavy, M. A., and Cleland, W. W. (1999) Can. J. Chem. 77, 967-977.
27. Cleland, W. W. (1980) Methods Enzymol. 64, 104-125.
28. Parmentier, L. E., Weiss, P. M., O'Leary, M. H., Schachman, H. K., and Cleland, W. W. (1992) Biochemistry 31, 6577-6584.
29. Gehring, H. (1986) Eur. J. Biochem. 159, 291-296.
30. Hermes, J. D., and Cleland, W. W. (1984) J. Am. Chem. Soc. 106, 7236-7264