Hyperosmolar solutions stimulate mucus secretion in the ferret trachea

Chest

Volumn 124, Issue 1, 2003, Pages 306-313

  Kishioka, Chikako ^a   Okamoto, Kosuke ^a   Kim, Jung Soo ^b   Rubin, Bruce K ^b  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Hypertonic saline solution; Inhalation administration; Mucociliary clearance; Mucus

Indexed keywords

LECTIN; MANNITOL; MUCIN; SODIUM CHLORIDE;

AEROSOL; ANIMAL TISSUE; ARTICLE; DOSE RESPONSE; ENZYME ASSAY; ENZYME RELEASE; FEMALE; FERRET; HYPEROSMOLALITY; LYSOSOME; MALE; MUCOCILIARY CLEARANCE; MUCUS; MUCUS SECRETION; NONHUMAN; PRIORITY JOURNAL; TRACHEA; TRACHEA MUCOSA;

EID: 0037484498     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.124.1.306     Document Type: Article

References (31)

1. Foot AB, Caul EO, Roome AP, et al. An assessment of sputum induction as an aid to diagnosis of respiratory infections in the immunocompromised child. J Infect 1992; 24: 49-54
2. Pin I, Gibson PG, Kolendowicz R, et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992; 47:25-29
3. Popov TA, Pizzichini MMM, Pizzichini E, et al. Some technical factors influencing the induction of sputum for cell analysis. Eur Respir J 1995; 8:559-565
4. Pavia D, Thomson ML, Clarke SW. Enhanced clearance of secretions from the human lung after the administration of hypertonic saline aerosol. Am Rev Respir Dis 1978; 117:199-203
5. Robinson M, Regnis JA, Bailey DL, et al. Effect of hypertonic saline, amiloride, and cough on mucociliary clearance in patients with cystic fibrosis. Am J Respir Crit Care Med 1996; 153:1503-1509
6. Robinson M, Hemming AL, Regnis JA, et al. Effect of increasing doses of hypertonic saline on mucociliary clearance in patients with cystic fibrosis. Thorax 1997; 52:900-903
7. Peatfield AC, Richardson PS, Wells UM. The effect of airflow on mucus secretion into the trachea of the cat. J Physiol 1986; 380:429-439
8. Wills P, Hall RL, Chan WM, et al. Sodium chloride increases the ciliary transportability of cystic fibrosis and bronchiectasis sputum on the mucus-depleted bovine trachea. J Clin Invest 1997; 99:9-13
9. Tomkiewicz RP, App EM, Zayas JG, et al. Amiloride inhalation therapy in cystic fibrosis. Am Rev Respir Dis 1993; 148:1002-1007
10. Hyde DM, Samuelson DA, Blakeney WH, et al. A correlative light microscopy, transmission microscopy and scanning electron microscopy study of the ferret lung. Scan Electron Microsc 1979; 3:891-898
11. Kishioka C, Okamoto K, Kin JS, et al. Regulation of secretion from mucous and serous cells in the excised ferret trachea. Respir Physiol 2001; 126:163-171
12. Kishioka C, Okamoto K, Hassett DJ, et al. Pseudomonas aeruginosa alginate is a potent secretagogue in the isolated ferret trachea. Pediatr Pulmonol 1999; 27:174-179
13. Kishioka C, Dorighi M, Rubin BK. Perflurooctyl bromide (perflubron) stimulates mucin secretion in the ferret trachea. Chest 1999; 115:823-828
14. Tom-Moy M, Basbaum CB, Nadel JA. Localization and release of lysozyme from ferret trachea: effects of adrenergic and cholinergic drugs. Cell Tissue Res 1983; 228:549-562
15. Eng PA, Morton J, Douglass JA, et al. Short term efficacy of ultrasonically nebulized hypertonic saline in cystic fibrosis. Pediatr Pulmonol 1996; 21:77-83
16. Leigh MW, Cheng P-W, Boat TF. Developmental changes of ferret tracheal mucin composition and biosynthesis. Biochemistry 1989; 28:9440-9446
17. Adler KB, Holden SW, Repine JE. Oxygen metabolites stimulate release of high-molecular-weight glycoconjugates by cell and organ cultures of rodent respiratory epithelium via an arachidonic acid-dependent mechanism. J Clin Invest 1990; 85:75-85
18. Lundgren JD, Kaliner M, Logun C, et al. Platelet activating factor and tracheobronchial respiratory glycoconjugate release in feline and human explants: involvement of the lipoxygenase pathway. Agents Actions 1990; 30:329-337
19. Yuta A, Ali M, Baraniuk JN. Hypertonic saline (HTS): comparison of nasal secretion in normal and atopy subjects [abstract]. Am J Respir Crit Care Med 1997; 155:A978
20. Umeno E, MacDonald DM, Nadel JA. Hypertonic saline increases vascular permeability in the rat trachea by producing neurogenic inflammation. J Clin Invest 1990; 85:1905-1908
21. Kowalski ML, Didier A, Kaliner MA. Neurogenic inflammation in the airways: I. Neurogenic stimulation induces plasma protein extravasation into rat airway lumen. Am Rev Respir Dis 1989; 140:101-109
22. Solway J, Lett AR. Sensory neuropeptides and airway function. J Appl Physiol 1991; 71:2077-2087
23. Barnes PJ. Neurogenic inflammation in airways. Int Arch Allergy Appl Immunol 1991; 94:303-309
24. Assouline G, Leibson V, Danon A. Stimulation of prostaglandin output from rat stomach by hypertonic solutions. Eur J Pharmacol 1977; 44:271-273
25. Gravelyn TR, Pan PM, Esheenbacher WL. Mediator release in an isolated segment in subjects with asthma. Am Rev Respir Dis 1988; 137:641-646
26. Folkesson HG, Kheradmand F, Matthay M. The effect of saltwater on alveolar epithelial barrier function. Am J Respir Crit Care Med 1994; 150:1555-1563
27. Daviskas E, Anderson SD, Gonda I, et al. Inhalation of hypertonic saline aerosol enhances mucociliary clearance in asthmatic and healthy subjects. Eur Respir J 1996; 9:725-732
28. Daviskas E, Anderson SD, Brannan JD, et al. Inhalation of dry-powder mannitol increases mucociliary clearance. Eur Respir J 1997; 10:2449-2454
29. Winters SL, Yeates DB. Roles of hydration, sodium, and chloride in regulation of canine mucoeiliary transport system. J Appl Physiol 1997; 83:1360-1369
30. Ingels KJ, Kortmann MJ, Nijziel MR, et al. Factors influencing ciliary beat measurements. Rhinology 1991; 29:17-26
31. van de Donk HJ, Zuidema J, Merkus FW. The influence of the pH and osmotic pressure upon tracheal ciliary beat frequency as determined with a new photo-electric registration device. Rhinology 1908; 18:93-104