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57
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0013350805
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note
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H8A(pAp) of 0.12 ppm at the N state and 0.124 ppm in D state.
-
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-
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58
-
-
0013440895
-
-
note
-
N-D: -0.069.
-
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-
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59
-
-
0013403607
-
-
note
-
pKa found is owing to slight changes in the microenvironment of the dimer and as well as the electronic properties trimers with respect to the monomer (see also ref 25).
-
-
-
-
60
-
-
0013394731
-
-
note
-
1p shows a detectable upfield shift over the pH range. Thus, the different pH-dependent tunibility of δH8 and δH2 of adenin-9-yl in pA and pAp, indicates the sequence-dependency owing to differential modulation of the pseudoaromatic character of adenine-9-yl in 2-4 by the effect of the nearest-neighbor.
-
-
-
-
61
-
-
0013349648
-
-
note
-
8,10 to pAp to experience the differential electrostatic interaction from the 5′terminal guanylate to minimize the Coulombic repulsion in GpApA (3). In contrast, the pAp in GpApC (4) is "offset stacked" such that imidazole part of pAp is within the influence of π-electron system of the guanylate anion, whereas the C5-C6 double bond of pC is also "offset stacked" with respect to pAp.
-
-
-
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63
-
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0037154986
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-
For review: Ramakrishnan, V. Cell 2002, 69, 557.
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66
-
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0013447370
-
-
note
-
8,10 which means that the imidazole edge of adenin-9-yl is within the stacking interaction of 9-guaninyl face.
-
-
-
-
67
-
-
0013352521
-
-
note
-
a unit on the terminal guanin-9-yl in Gp in our case) upon an increase of the total number of phosphates in the molecule as a result of chain elongation.
-
-
-
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