Automated online dual-column extraction coupled with teicoplanin stationary phase for simultaneous determination of (R)- and (S)-propranolol in rat plasma using liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 788, Issue 2, 2003, Pages 317-329

  Xia, Yuan Qing ^a   Bakhtiar, Ray ^a   Franklin, Ronald B ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Enantiomer separation; Propranolol; Stationary phases, LC; Teicoplanin

Indexed keywords

BIOASSAY; BODY FLUIDS; COLUMN CHROMATOGRAPHY; ORGANIC COMPOUNDS;

ENANTIOMERS;

LIQUID CHROMATOGRAPHY;

PROPRANOLOL; TEICOPLANIN;

ACCURACY; ANALYTICAL EQUIPMENT; ANIMAL EXPERIMENT; ARTICLE; AUTOANALYSIS; BLOOD SAMPLING; CALIBRATION; CHIRALITY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG PURIFICATION; ENANTIOMER; EXTRACTION; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; ONLINE ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RACEMIC MIXTURE; RAT; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY; TIME; VALIDATION PROCESS;

EID: 0037466751     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-0232(03)00036-9     Document Type: Article

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