Structural features of human initiation factor 4E, studied by X-ray crystal analyses and molecular dynamics simulations

Journal of Molecular Biology

Volumn 328, Issue 2, 2003, Pages 365-383

  Tomoo, Koji ^a   Shen, Xu ^a   Okabe, Koumei ^a   Nozoe, Yoshiaki ^a   Fukuhara, Shoichi ^a   Morino, Shigenobu ^a   Sasaki, Masahiro ^b   Taniguchi, Taizo ^b,c   Miyagawa, Hiroo ^d   Kitamura, Kunihiro ^d   Miura, Kin Ichiro ^e   Ishida, Toshimasa ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b Behavioral and Medical Sciences Research Consortium   (Japan)

^c KOBE UNIVERSITY   (Japan)

^d TAISHO PHARMACEUTICAL CO LTD   (Japan)

^e Proteios Research Inc   (Japan)

Author keywords

Initiation factor 4E; m7GpppA; m7GTP; Molecular dynamics simulation; X ray crystal structure

Indexed keywords

ADENOSINE; INITIATION FACTOR 4E; MESSENGER RNA; NUCLEOTIDE; PHOSPHATE; TRIPHOSPHATE; UNCLASSIFIED DRUG; WATER;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME BINDING; HYDROGEN BOND; IONIZATION; MOLECULAR DYNAMICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN STRUCTURE; RNA CAPPING; SIMULATION; X RAY CRYSTALLOGRAPHY;

EID: 0037466314     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(03)00314-0     Document Type: Article

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