N-benzoyl amino acids as LFA-1/ICAM inhibitors 1: Amino acid structure-activity relationship

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 6, 2003, Pages 1015-1018

  Burdick, Daniel J ^a   Paris, Ken ^a   Weese, Kenneth ^a   Stanley, Mark ^a   Beresini, Maureen ^a   Clark, Kevin ^a   McDowell, Robert S ^a,b   Marsters Jr , James C ^a   Gadek, Thomas R ^a  

^a GENENTECH INC   (United States)

^b Sunesis Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; HISTIDINE; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; PROTEIN SYNTHESIS INHIBITOR;

ARTICLE; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 0037463763     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00084-2     Document Type: Article

References (16)

1. Hynes R.O. Cell. 48:1987;549.
2. Mazzone A., Ricevute G. Haematology. 80:1995;161.
3. Springer T.A. Nature. 346:1990;425.
4. Carlos T.M., Harlan J.M. Blood. 84:1994;2068.
5. Gahmberg C.G., Tolvanen M., Kotovuori P. Eur. J. Biochem. 245:1997;215.
6. Bevilacqua M.P., Nelson R.M., Mannori G. Ann. Rev. Med. 45:1994;361.
7. Cornejo C.J., Winn R.K., Harlan J.M. Adv. Pharmacol. 39:1997;99.
8. Henricks P.A., Nijkamp F.P. Eur. J. Pharmacol. 344:1998;1.
9. Liu G. Drugs Future. 26:2001;767.
10. Liu G. Expert Opin. Ther. Pat. 11:2001;1383.
11. Yun, W.; Desai, B. B.; Du, Y.; Fotouhi, N.; Gillespie, P.; Guthrie, R. W.; Huang, K.; Kolinsky, K.; Li, S. H.; Mennona, F. A.; Perrota, A.; Pietranico-Cole, S. L.; Portland, L.; Vermeulen, J. Abstracts of Papers, 224 National Meeting of the American Chemical Society, Boston, MA; American Chemical Society: Washington, DC, 2002.
12. Gadek T.R., Burdick D.J., McDowell R.S., Stanley M.S., Marsters J. C., Jr., Paris K.J., Oare D.A., Reynolds M.E., Ladner C., Zioncheck K.A., Lee W.P., Gribling P., Dennis M.S., Skelton N.J., Tumas D.B., Clark K.R., Keating S.M., Beresini M.H., Tilley J.W., Presta L.G., Bodary S.C. Science. 295:2002;1086.
13. Burdick, D. J. In PCT Int. Appl. WO9949856, 1999.
14. Fisher K.L., Lu J., Riddle L., Kim K.J., Presta L.G., Bodary S.C. Mol. Biol. Cell. 8:1997;501.
15. Carpino L., Han G. J. Org. Chem. 37:1981;3404.
16. Fields G., Noble R.L. Int. J. Peptide Protein Res. 35:1990;161.