Whipple's disease - From enigma to genomics

Lancet

Volumn 361, Issue 9358, 2003, Pages 632-

  Schaffner, Andreas ^a   Schneemann, Markus ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMPLICON; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIUM; DIAGNOSTIC TEST; ECOLOGY; ELECTRON MICROSCOPY; FECES ANALYSIS; FIBROBLAST; GENOMICS; IMMUNE DEFICIENCY; IMMUNE SYSTEM; INTESTINE LIPODYSTROPHY; LIPID METABOLISM; LIPODYSTROPHY; MACROPHAGE; MONONUCLEAR PHAGOCYTE; NONHUMAN; NOTE; PATHOGENESIS; PHAGOCYTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SALIVA; SEQUENCE ANALYSIS; TROPHERYMA WHIPPELII; VIRULENCE;

EID: 0037460691     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(03)12616-5     Document Type: Note

References (12)

1. Whipple G.H. A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acids in the intestinal and mesenteric lymphatic tissues. Johns Hopkins Hosp Bull. 18:1907;382-393.
2. Dobbins W.O. Whipple. 1987;CC Thomas, s disease. Springfield, IL.
3. Wilson K.H., Blitchington R., Frothingham R., Wilson J.A.P. Phylogeny of the Whipple's disease-associated bacterium. Lancet. 338:1991;474-475.
4. Relman D.A., Schmidt T.M., MacDermott R.P., Falkow S. Identification of the uncultured bacillus of Whipple's disease. N Engl J Med. 327:1992;293-301.
5. Schoedon G., Goldenberger D., Forrer R., et al. Deactivation of macrophages with interleukin-4 is the key to the isolation of Tropheryma whippelii. J Infect Dis. 176:1997;672-677.
6. Raoult D., Birg M.L., La Scola B., et al. Cultivation of the bacillus of Whipple's disease. N Engl J Med. 342:2000;620-625.
7. The Wellcome Trust Sanger Institute. Tropheryma whippelii, 2002: http://www.sanger.ac.uk/Projects/T_whippelii/ (accessed Feb 11, 2003).
8. Maiwald M., Schuhmacher F., Ditton H.J., von Herbay A. Environmental occurrence of the Whipple's disease bacterium (Tropheryma whippelii). Appl Environ Microbiol. 64:1998;760-762.
9. Maibach R.C., Dutly F., Altwegg M. Detection of Tropheryma whipplei DNA in feces by PCR using a target capture method. J Clin Microbiol. 40:2002;2466-2471.
10. Street S., Donoghue H.D., Neild G.H. Tropheryma whippelii DNA in saliva of healthy people. Lancet. 354:1999;1178-1179.
11. Zinkernagel AS, Gmür R, Fenner L, Schaffner A, Schoedon G, Schneemann M. Marginal and subgingival plaque - a natural habitat of Tropheryma whipplei? Infection (in press).
12. Marth T., Kleen N., Stallmach A., et al. Dysregulated peripheral and mucosal Th1/Th2 response in Whipple's disease. Gastroenterology. 123:2002;1468-1477.