Highly enantioenriched tetrahydropyridines from chiral organosilanes: Application to the synthesis of quinolizidine alkaloid (-)-217A

Journal of the American Chemical Society

Volumn 125, Issue 3, 2003, Pages 626-627

  Huang, Hongbing ^a,b   Spande, Thomas F ^a,b   Panek, James S ^a,b  

^a Boston University   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; LEWIS ACID; PYRIDINE DERIVATIVE; QUINOLIZIDINE DERIVATIVE; SILANE DERIVATIVE;

ARTICLE; COMPLEX FORMATION; ENANTIOMER; ENANTIOSELECTIVITY; LOW TEMPERATURE PROCEDURES; REACTION ANALYSIS; REACTION OPTIMIZATION; STEREOCHEMISTRY;

ALKALOIDS; PYRIDINES; QUINOLIZINES; SILANES; STEREOISOMERISM;

EID: 0037460173     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja028937i     Document Type: Article

References (26)

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16. 2, rt, 0.5 h).
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19. Enantiomeric excess (ee) analysis was conducted by chiral HPLC analysis. The detailed experimental procedure including ee analysis can be found in the Supporting Information.
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26. See Supporting Information for details.