Synthesis and characterization of new ruthenium complexes with active ligands against Chagas' disease

Inorganica Chimica Acta

Volumn 344, Issue , 2003, Pages 85-94

  Otero, Lucía ^a   Noblia, Pabla ^a   Gambino, Dinorah ^a   Cerecetto, Hugo ^a   González, Mercedes ^a   Ellena, Javier A ^b   Piro, Oscar E ^c  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FACULTAD DE CIENCIAS EXACTAS   (Argentina)

Author keywords

Chagas' disease chemotherapy; Ruthenium complexes; Semicarbazone complexes

Indexed keywords

ATOMS; CHELATION; CHEMOTHERAPY; CONDENSATION REACTIONS; CRYSTALS; LIGANDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS (CHEMICAL);

13C NMR SPECTROSCOPY; CHAGAS' DISEASE; CRYSTAL AND MOLECULAR STRUCTURE; OCTAHEDRAL ENVIRONMENT; RUTHENIUM COMPLEXES; SEMICARBAZONES; SYNTHESIS AND CHARACTERIZATIONS; X-RAY DIFFRACTION METHOD;

RUTHENIUM COMPOUNDS;

ALCOHOL; RUTHENIUM COMPLEX; TOLUENE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHAGAS DISEASE; CHEMICAL ANALYSIS; CRYSTAL STRUCTURE; DRUG SYNTHESIS; ELECTRONICS; INFRARED SPECTROSCOPY; MOLECULAR BIOLOGY; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY DIFFRACTION;

EID: 0037455943     PISSN: 00201693     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-1693(02)01277-X     Document Type: Article

References (27)

1. Braga M.S., Lauria-Pires L., Argañaraz E.R., Nascimento R.J., Teixeira A.R. Rev. Inst. Med. Trop. Sao Paulo. 42:2000;157.
2. Gorla N.B., Ledesma O.S., Barbieri G.P., Larripa I.B. Mutat. Res. 2241:1989;263.
3. Olea-Azar C., Atria A.M., Mendizabal F., Di Maio R., Caracalli I., Seoane G., Cerecetto H. Spectrosc. Lett. 31:1998;99.
4. Cerecetto H., Di Maio R., Ibarruri G., Seoane G., Denicola A., Quijano C., Peluffo G., Paulino M. Farmaco. 53:1998;89.
5. Farrell N. Transition Metal Complexes as Drugs and Chemotherapeutic Agents. 11:1989;230 Kluwer Academic Publishers, London.
6. Maestroni G., Alessio E., Sava G., Pacor S., Coluccia M. Metal Complexes in Cancer Chemotherapy. 1993;159-185 VCH, Weinheim.
7. Sánchez Delgado R., Lazardi K., Rincón L., Urbina J. J. Med. Chem. 36:1993;2041.
8. Sánchez Delgado R., Navarro M., Lazardi K., Atencio R., Caparelli M., Vargas F., Urbina J., Boulliez A., Noels A., Masi D. Inorg. Chim. Acta. 1998;275.
9. Navarro M., Lehman T., Cisneros-Fajardo E., Fuentes A., Sánchez Delgado R., Urbina J. Polyhedron. 19:2000;2319.
10. Castilla A.J., Mesa-Valle C.M., Sanchez Moreno M., Arnedo T., Rosales M., Mascaro C., Craciunescu D., Osuna A. Arzneim.-Forsch/Drug Res. 46:1996;990.
11. Mesa-Valle C.M., Moradela V., Craciunescu D., Alonso M.P., Osuna A. Arzneim.-Forsch/Drug Res. 43:1993;1010.
12. Cerecetto H., Di Maio R., González M., Risso M., Sagrera G., Seoane G., Denicola A., Peluffo G., Quijano C., Stoppani A., Paulino M., Olea-Azar C., Basombrio M.A. Eur. J. Med. Chem. 35:2000;343.
13. Henderson G., Ulrich P., Fairlamb A., Rosemberg I., Pereira M., Sela M., Cerami A. Proc. Natl. Acad. Sci. USA. 85:1998;5374.
14. Basuli F., Peng S., Battacharya S. Inorg. Chem. 40:2001;1126.
15. Evans I., Spencer A., Wilkinson G. J. Chem. Soc., Dalton Trans. 1973;204.
16. Wavefunction, Inc., 18401 Von Karman Avenue, Suite 370, Irvine, CA 92612, USA.
17. Blessing R.H. Acta Crystallogr., A. 51:1995;33.
18. Otwinowski Z., Minor W. Methods in Enzymology. 276:1997;307-326 Academic Press, New York.
19. G.M. Sheldrick, SHELXS-97. Program for Crystal Structure Resolution, University of Göttingen, Göttingen, Germany, 1997.
20. G.M. Sheldrick, SHELXL-97. Program for Crystal Structures Analysis, University of Göttingen, Göttingen, Germany, 1997.
21. El Mostapha Jouad, A. Riou, M. Allain, M A. Khan, G. Bouet, Polyhedron 20 (2001) 67.
22. Alessio E., Mestroni G., Nardin G., Attia W., Calligaris M., Sava G., Zorzet S. Inorg. Chem. 27:1988;4099.
23. Padhyé S., Kauffman G. Coord. Chem. Rev. 63:1985;127.
24. C.K. Johnson, ORTEP, Report ORNL-3794, Oak Ridge, TN, 1965.
25. Calligaris M., Carugo O. Coord. Chem. Rev. 153:1996;83.
26. Wolfgang H. Arch. Pharm. 325:1992;769.
27. H. Cerecetto, M. Gonzalez, unpublished results.