The carboxyl side chain of glutamate 681 interacts with a chloride binding modifier site that allosterically modulates the dimeric conformational state of band 3 (AE1). Implications for the mechanism of anion/proton cotransport

Biochemistry

Volumn 42, Issue 6, 2003, Pages 1589-1602

  Salhany, James M ^a,b   Sloan, Renee L ^a   Cordes, Karen S ^a  

^a VA NEBRASKA WESTERN IOWA HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOASSAY; CHEMICAL MODIFICATION; CONFORMATIONS; DIMERS; FLUORESCENCE; ION EXCHANGE; RATE CONSTANTS; TRANSPORT PROPERTIES;

NEUTRALIZATION REACTIONS;

BIOCHEMISTRY;

4,4' DIBENZAMIDO 2,2' STILBENEDISULFONATE; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; ANTIPORTER; BICARBONATE; CARBOXYL GROUP; CHLORIDE; ERYTHROCYTE BAND 3 PROTEIN; GLUTAMIC ACID; SODIUM BOROHYDRIDE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ALLOSTERISM; ANION TRANSPORT; ARTICLE; BINDING SITE; CHEMICAL MODIFICATION; CHLORIDE TRANSPORT; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FLUORESCENCE; HUMAN; HUMAN CELL; IONIC STRENGTH; PRIORITY JOURNAL; PROCESS DESIGN; PROTON TRANSPORT; QUANTUM CHEMISTRY; REACTION ANALYSIS; SPECTROSCOPY; TIME; TITRIMETRY;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; 4-ACETAMIDO-4'-ISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID; ALLOSTERIC REGULATION; ALLOSTERIC SITE; ANION EXCHANGE PROTEIN 1, ERYTHROCYTE; BOROHYDRIDES; CHLORIDES; DIMERIZATION; ERYTHROCYTE MEMBRANE; GLUTAMIC ACID; HUMANS; INDICATORS AND REAGENTS; ION TRANSPORT; ISOXAZOLES; KINETICS; MODELS, CHEMICAL; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SUBUNITS; PROTONS; SPECTROMETRY, FLUORESCENCE;

EID: 0037452558     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0205294     Document Type: Article

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