trans-targeting of the phage Mu repressor is promoted by conformational changes that expose its ClpX recognition determinant

Journal of Biological Chemistry

Volumn 278, Issue 3, 2003, Pages 1612-1617

  Marshall Batty, Kimberly R ^b   Nakai, Hiroshi ^a  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; FLUORESCENCE; MUTAGENESIS; ORGANIC ACIDS; PROTEINS;

PHOSPHORYLATION;

GENETIC ENGINEERING;

2 (4' MALEIMIDYLANILINO)NAPHTHALENE 6 SULFONIC ACID; CHAPERONE; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENDOPEPTIDASE CLPX; FLUORESCENT DYE; PROTEIN VIR; REPRESSOR PROTEIN; UNCLASSIFIED DRUG; 2-(4'-MALEIMIDYLANILINO)NAPHTHALENE-6-SULFONIC ACID; 8 ANILINO 1 NAPHTHALENESULFONIC ACID; ADENOSINE TRIPHOSPHATASE; CLPX PROTEIN, E COLI; ENDOPEPTIDASE CLP; ESCHERICHIA COLI PROTEIN; PRIMER DNA;

ARTICLE; BACTERIOPHAGE MU; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; GENE FUNCTION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REPRESSOR GENE; WILD TYPE; AMINO ACID SEQUENCE; BINDING SITE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY;

ENTEROBACTERIA PHAGE MU; UNIDENTIFIED BACTERIOPHAGE; VIR;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANILINO NAPHTHALENESULFONATES; BACTERIOPHAGE MU; BASE SEQUENCE; BINDING SITES; DNA PRIMERS; ENDOPEPTIDASE CLP; ESCHERICHIA COLI PROTEINS; FLUORESCENT DYES; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0037449804     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209352200     Document Type: Article

References (48)

1. Gottesman, S., Clark, W. P., de Crécy-Lagard, V., and Maurizi., M. R. (1993) J. Biol. Chem. 268, 22618-22626
2. Kim, Y. I., Burton, R. E., Burton, B. M., Sauer, R. T., and Baker, T. A. (2000) Mol. Cell 5, 639-648
3. Singh, S. K., Grimaud, R., Hoskins, J. R., Wickner, S., and Maurizi, M. R. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 8898-8903
4. Wojtkowiak, D., Georgopoulos, C., and Zylicz, M. (1993) J. Biol. Chem. 268, 22609-22617
5. Wang, J., Hartling, J. A., and Flanagan, J. M. (1997) Cell 91, 447-456
6. Grimaud, R., Kessel, M., Beuron, F., Steven, A. C., and Maurizi, M. R. (1998) J. Biol. Chem. 273, 12476-12481
7. Flynn, J. M., Levchenko, I., Seidel, M., Wickner, S. H., Sauer, R. T., and Baker, T. A. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 10584-10589
8. Gonciarz-Swiatek, M., Wawrzynow, A., Um, S. J., Learn, B. A., McMacken, R., Kelley, W. L., Georgopoulos, C., Sliekers, O., and Zylicz, M. (1999) J. Biol. Chem. 274, 13999-14005
9. Levchenko, I., Yamauchi, M., and Baker, T. A. (1997) Genes Dev. 11, 1561-1572
10. Gonzalez, M., Rasulova, F., Maurizi, M. R., and Woodgate, R. (2000) EMBO J. 19, 5251-5258
11. Bearson, S. M., Benjamin, W. H., Jr., Swords, W. E., and Foster, J. W. (1996) J. Bacteriol. 178, 2572-2579
12. Muffler, A., Fischer, D., Altuvia, S., Storz, G., and Hengge-Aronis, R. (1996) EMBO J. 15, 1333-1339
13. Pratt, L. A., and Silhavy, T. J. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 2488-2492
14. Zhou, Y., Gottesman, S., Hoskins, J. R., Maurizi, M. R., and Wickner, S. (2001) Genes Dev. 15, 627-637
15. Levchenko, I., Seidel, M., Sauer, R. T., and Baker, T. A. (2000) Science 289, 2354-2356
16. Geuskens, V., Vogel, J. L., Grimaud, R., Desmet, L., Higgins, N. P., and Toussaint, A. (1991) J. Bacteriol. 173, 6578-6585
17. Geuskens, V., Mhammedi-Alaoui, A., Desmet, L., and Toussaint, A. (1992) EMBO J. 11, 5121-5127
18. Mhammedi-Alaoui, A., Pato, M., Gama, M.-J., and Toussaint, A. (1994) Mol Microbiol. 11, 1109-1116
19. O'Handley, D., and Nakai, H. (2002) J. Mol. Biol. 322, 311-324
20. Symonds, N., Toussaint, A., van de Putte, P., and Howe, M. M. (eds) (1987) Phage Mu, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
21. Krause, H. M., and Higgins, N. P. (1986) J. Biol. Chem. 261, 3744-3752
22. Leung, P. C., Teplow, D. B., and Harshey, R. M. (1989) Nature 338, 656-658
23. Mizuuchi, M., and Mizuuchi, K. (1989) Cell 58, 399-408
24. Lamrani, S., Ranquet, C., Gama, M. J., Nakai, H., Shapiro, J. A., Toussaint, A. and Maenhaut-Michel, G. (1999) Mol. Microbiol. 32, 327-343
25. Shapiro, J. A. (1984) Mol. Gen. Genet. 194, 79-90
26. Maenhaut-Michel, G., and Shapiro, J. A. (1994) EMBO J. 13, 5229-5239
27. Shapiro, J. A., and Leach, D. (1990) Genetics 126, 293-299
28. Keiler, K. C., Waller, P. R. H., and Sauer, R. T. (1996) Science 271, 990-993
29. Atkins, J. F., and Gesteland, R. F. (1996) Nature 379, 769-771
30. Jentsch, S. (1996) Science 271, 955-956
31. Welty, D. J., Jones, J. M., and Nakai, H. (1997) J. Mol. Biol. 272, 31-41
32. Alazard, R., Ebel, C., Venien-Bryan, V., Mourey, L., Samama, J. P., and Chandler, M. (1998) Eur. J. Biochem. 252, 408-415
33. Rousseau, P., Bétermier, M., Chandler, M., and Alazard, R. (1996) J. Biol. Chem. 271, 9739-9745
34. Rai, S. S., O'Handley, D., and Nakai, H. (2001) J. Mol. Biol. 312, 311-322
35. Vogel, J. L., Geuskens, V., Desmet, L., Higgins, N. P., and Toussaint, A. (1996) Genetics 142, 661-672
36. Ranquet, C., Geiselmann, J., and Toussaint, A. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 10220-10225
37. Mukhopadyay, B., Marshall-Batty, K. R., Kim, B. D., O'Handley, D., and Nakai, H. (2002) Mol. Mierobiol., in press
38. Vogel, J. L., Li, Z. J., Howe, M. M., Toussaint, A., and Higgins, N. P. (1991) J. Bacteriol. 173, 6568-6577
39. Kelman, Z., Naktinis, V., and O'Donnell, M. (1995) Methods Enzymol. 262, 430-442
40. Hiratsuka, T. (1992) J. Biol. Chem. 267, 14941-14948
41. Hoskins, J. R., Yanagihara, K., Mizuuchi, K., and Wickner, S. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 11037-11042
42. Prusiner, S. B. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13363-13383
43. Osherovich, L. Z., and Weissman, J. S. (2002) Dev. Cell 2, 143-151
44. Uptain, S. M., and Lindquist, S. (2002) Annu. Rev. Microbiol. 56, 703-741
45. Wickner, R. B., Taylor, K. L., Edskes, H. K., Maddelein, M. L., Moriyama, H., and Roberts, B. T. (2000) J. Struct. Biol. 130, 310-322
46. Cohen, F. E., and Prusiner, S. B. (1998)Annu. Rev. Biochem. 67, 793-819
47. Ilangovan, U., Wojciak, J. M., Connolly, K. M., and Clubb, R. T. (1999) Biochemistry 38, 8367-8376
48. Rousseau, P., Laachouch, J. E., Chandler, M., and Toussaint, A. (2002) Res. Microbiol. 153, 511-518