C-terminal deletions can suppress temperature-sensitive mutations and change dominance in the phage Mu repressor

Genetics

Volumn 142, Issue 3, 1996, Pages 661-672

  Vogel, Jodi L ^a,b   Geuskens, Vincent ^c   Desmet, Lucie ^c   Higgins, N Patrick ^a,e   Toussaint, Ariane ^c,d  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c U Transposition Bacterienne   (Belgium)

^d UNIV GRENOBLE ALPES   (France)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; BACTERIOPHAGE MU; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA BINDING; ESCHERICHIA COLI; GENE DELETION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REPRESSOR GENE; TEMPERATURE DEPENDENCE; TEMPERATURE SENSITIVE MUTANT;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; BACTERIOPHAGE MU; BASE SEQUENCE; DNA, VIRAL; ENDOPEPTIDASE CLP; GENE DELETION; GENE EXPRESSION REGULATION, VIRAL; MOLECULAR SEQUENCE DATA; REPRESSOR PROTEINS; SERINE ENDOPEPTIDASES; TEMPERATURE SENSE; VIRAL PROTEINS;

EID: 0029905535     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. ALAZARD, R., M. BETERMIER and M. CHANDLER, 1992 Escherichia coli integration host factor stabilizes bacteriophage Mu repressor interactions with operator DNA in vitro. Mol. Microbiol. 6: 1707-1714.
2. ALBER, T., S. DAO-PIN, J. A. NYE, D. C. MUCHMORE and B. W. MATTHEWS, 1987 Temperature-sensitive mutations of bacteriophage T4 lysozyme occur at sites with low mobility and low solvent accessibility in the folded protein. Biochem. 26: 3754-3758.
3. APPLEYARD, R. K., 1954 Segregation of lambda lysogenicity during bacterial recombination in Escherichia coli K12. Genetics 39: 429-439.
4. BALL, C., R. OSUNA, K. FERGUSON and R. JOHNSON, 1992 Dramatic changes in Fis levels upon nutrient upshift in Escherichia coli. J. Bacteriol. 174: 8043-8056.
5. BETERMIER, M., I. POQUET, R. ALAZARD and M. CHANDLER, 1993 Involvement of Escherichia coli FIS protein in maintenance of bacteriophage Mu lysogeny by the repressor: control of early transcription and inhibition of transposition. J. Bacteriol. 175: 3798-3811.
6. CLUBB, R. T , J. G. OMICHINSKI, H. SAVILAHTI, K. MIZUUCHI, A. M. GRONENBORN et al., 1994 A novel class of winged helix-turn-helix protein: the DNA-binding domain of Mu transposase. Structure 2: 1041-1048.
7. COULONDRE, C., and J. H. MILLER, 1977 Genetic studies of the lac repressor III. Additional correlation of mutational sites with specific amino acid residues. J. Mol. Biol. 117: 525-575.
8. CRAIG, N. L., and J. W. ROBERTS, 1980 E. coli recA protein-directed cleavage of phage λ repressor requires polynucleotide. Nature 283: 26-30.
9. CRAIGIE, R., M. MIZUUCHI and K. MIZUUCHI, 1984 Site-specific recognition of the bacteriophage Mu ends by the Mu A protein. Cell 39: 387-394
10. DEGNEN, G. E., and E. C. COX, 1974 Conditional mutator gene in Escherichia coli: isolation, mapping and effector studies. J. Bacteriol. 117: 477-487.
11. DERSCH, P., K. SCHMIDT and E. BREMER, 1993 Synthesis of the Escherichia coli K-12 nucleoid-associated DNA-binding protein H-NS is subjected to growth-phase control and autoregulation. Mol. Microbiol. 8: 875-889.
12. FALCONI, M., V. MCGOVERN, C. GUALERZI, D. HILLYARD and N. P. HIGGINS, 1991 Mutations altering chromosomal protein H-NS induce mini-Mu transposition. New Biol. 3: 615-625.
13. KINKEL, S., and R. JOHNSON, 1992 The Fis protein: it's not just for DNA inversion anymore. Mol. Microbiol. 6: 3257-3265.
14. FOSTER, P. L., and J. CAIRNS, 1994 The occurrence of heritable Mu excisions in starving cells of Escherichia coli. EMBO J. 13: 5240-5244
15. GAMA, M. J , A. TOUSSAINT and N. P. HIGGINS, 1992 Stabilization of bacteriophage Mu repressor-operator complexes by the Escherichia coli integration host factor protein. Mol. Microbiol. 6: 1715-1722.
16. GEUSKENS, V., J. L. VOGEL, R. GRIMAUD, L. DESMET, N. P. HIGGINS et al. 1991 Frameshift mutations in the bacteriophage Mu repressor gene can confer a trans-dominant virulent phenotype to the phage. J. Bacteriol. 173: 6578-6585.
17. GEUSKENS, V., A. MHAMMEDI-ALAOUI, L. DESMET and A. TOUSSAINT, 1992 Virulence in bacteriophage Mu: a case of trans-dominant proteolysis by the Escherichia coli Clp serine protease. EMBO J. 11: 5121-5127.
18. HARSHEY, R. M., E. D. GETZOFF, D. L. BALDWIN, J. L. MILLER and G. CHACONAS, 1985 Primary structure of the phage Mu transposase: homology to Mu repressor. Proc. Natl. Acad. Sci. USA 82: 7676-7680.
19. HEINZ, D., W. BAASE and B. MATTHEWS, 1992 Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence. Proc. Natl. Acad. Sci. USA 89: 3751-3755.
20. HIGGINS, N P., 1992 Death and transfiguration among bacteria. Trends Biochem. Sci. 17: 207-211.
21. HOHN, B., 1979 In vitro packaging of λ and cosmid DNA. Methods Enzymol. 68: 299-343.
22. KRAUSE, H. M., and N. P. HIGGINS, 1984 On the Mu repressor and early DNA intermediates of transposition. Cold Spring Harbor Symp. Quant. Biol. 49: 827-834.
23. KRAUSE, H. M., and N. P. HIGGINS, 1986 Positive and negative regulation of the Mu operator by Mu repressor and Escherichia coli integration host factor. J. Biol. Chem. 261: 3744-3752.
24. LEACH, D., and N. SYMONDS, 1979 The isolation and characterization of a plaque-forming derivative of bacteriophage Mu carrying a fragment of Tn3 conferring ampicillin resistance. Mol. Gen. Genet. 172: 172-179.
25. LEUNG, P. C., D. B. TEPLOW and R. M. HARSHEY, 1989 Interaction of distinct domains in Mu transposase with Mu DNA ends and an internal transpositional enhancer. Nature 338: 656-658.
26. LIN, W. A., and R. T. SAUER, 1991 The role of internal packing interactions in determining the structure and stability of a protein. J. Mol. Biol. 219: 359-376.
27. LITTLE, J. W., 1984 Autodigestion of lexA and phage 1 repressors Proc. Natl. Acad. Sci. USA 81: 1375-1379.
28. LITTLE, J., 1993 LexA cleavage and other self-processing reactions. J. Bacteriol. 175: 4943-4950.
29. MAENHAUT-MICHEL, G., and J. A. SHAPIRO, 1994 The roles of starvation and selective substrates in the emergence of araB - lacZ fusion clones. EMBO J. 13: 5229-5239.
30. MHAMMEDI-ALAOUI, A., M. L. PATO, M.-J. GAMA and A. TOUSSAINT, 1994 A new component of bacteriophage Mu replicative transposition machinery, the Escherichia coli ClpX protein. Mol. Microbiol. 11: 1109-1116.
31. MILLER, J. H., 1972 Experiments in Molecular Genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
32. MITTLER, J. E., and R. E. LENSKI, 1990 New data on excisions of Mu from E. coli MCS2 cast doubt on directed mutation hypothesis. Nature 344: 173-175.
33. MIZUUCHI, M., and K. MIZUUCHI, 1989 Efficient Mu transposition requires interaction of transposase with a DNA sequence at the Mu operator: implications for regulation. Cell 58: 399-408.
34. MUSTER, C J., and J. A SHAPIRO, 1981 Recombination involving transposable elements: on replicon fusion Cold Spring Harbor Symp. Quant. Biol. 40: 239-242.
35. PAOLOZZI, L., and N. SYMONDS, 1986 The SE region, pp. 53-62 in Bacteriophage Mu, edited by N SYMONDS, A. TOUSSAINT, P. VAN DE PUTTE and M. M HOWE. Cold Spring Harbor Laboratories, Cold Spring Harbor, NY.
36. ROSS, W., S. H. SHORE and M. M. HOWE, 1986 Mutants of Escherichia coli defective for replicative transposition of bacteriophage Mu. J. Bacteriol. 167: 905-919
37. SAUER, R. T., S. JORDAN and C. O. PABO, 1990 λ repressor: a model system for understanding protein-DNA interactions and protein stability. Adv. Protein Chem. 40: 1-61.
38. SHAPIRO, J. A., 1984 Observations on the formation of clones containing araB-lacZ cistron fusions. Mol. Gen. Genet. 194: 79-90.
39. SHAPIRO, J., 1992 Differential action and differential expression of DNA polymerase I during Escherichia coli colony development. J. Bacteriol. 174: 7262-7272.
40. SHAPIRO, J. A., 1993 A role for the Clp protease in activating Mu-mediated DNA rearrangements. J. Bacteriol. 175: 2625-2631.
41. SHAPIRO, J. A., 1994 Pattern and control in bacterial colonies. Sci. Prog. 76: 399-424.
42. SHAPIRO, J. A., and N. P. HIGGINS, 1989 Differential activity of a transposable element in Escherichia coli colonies. J. Bacteriol. 171: 5975-5986.
43. SIMONS, R. W., F. HOUMAN and N. KLECKNER, 1987 Improved single and multicopy lac-based cloning vectors for protein and operon fusions. Gene 53: 85-96.
44. SUSSKIND, M M., and P. YOUDERIAN, 1983 Bacteriophage P22 antirepressor and its control, pp. 251-277 in Lambda 11, edited by R. W. HENDRIX, J. W. ROBERTS, F. W. STAHL and R. A. WEISBERG. Cold Spring Harbor Laboratories, Cold Spring Harbor, NY.
45. TAYLOR, A L., 1963 Bacteriophage-induced mutation in E. coli. Proc. Natl. Acad. Sci. USA 50: 1043-1051.
46. TOUSSAINT, A., L. DESMET, M. FAELEN, R. ALAZARD, M. CHANDLER et al. 1987 In vivo mutagenesis of bacteriophage Mu transposase. J. Bacteriol. 169: 5700-5707.
47. VAN VLIET, F., M. COUTURIER, L. DESMET, M. FAELEN and A. TOUSSAINT, 1978 Virulent mutants of temperate phage Mu-1. Mol. Gen. Genet. 160: 195-202.
48. VOGEL, J. L., J. L. ZHU, M. M. HOWE, A. TOUSSAINT and N. P. HIGGINS, 1991 Temperature sensitive mutations in the bacteriophage Mu c repressor locate a 63-amino-acid DNA-binding domain. J. Bacteriol. 173: 6568-6577.
49. YANISCH-PERRON, C., J. VIERA and J. MESSING, 1985 Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M12mp18 and pUC19 vectors. Gene 33: 103-119.