A comparison of the quantitative methods for the analysis of the platinum-containing anticancer drug {cis-[amminedichloro(2-methylpyridine)]-platinum(II)} (ZD0473) by HPLC coupled to either a triple quadrupole mass spectrometer or an inductively coupled plasma mass spectrometer

Analytical Chemistry

Volumn 75, Issue 6, 2003, Pages 1463-1469

  Smith, Christopher J ^a   Wilson, Ian D ^a   Abou Shakra, Fadi ^b   Payne, Richard ^a   Parry, Tony C ^a   Sinclair, Peta ^a   Roberts, David W ^a  

^a ASTRAZENECA   (United Kingdom)

^b MICROMASS UK LTD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ANALYSIS; INDUCTIVELY COUPLED PLASMA; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLATINUM;

AQUA COMPOUNDS;

DRUG PRODUCTS;

AMMINEDICHLORO(2 METHYLPYRIDINE)PLATINUM; ANTINEOPLASTIC AGENT;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; BODY FLUID; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; MALE; MASS SPECTROMETRY; NONHUMAN; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SPIKE; ULTRAFILTRATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; DRUG MONITORING; MASS SPECTROMETRY; PLATINUM COMPOUNDS;

EID: 0037444517     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac025837m     Document Type: Article

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