Gαq and Gα11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme

Developmental Biology

Volumn 255, Issue 2, 2003, Pages 230-237

  Ivey, Kathryn ^a,b   Tyson, Brandi ^a   Ukidwe, Pallavi ^b   McFadden, David G ^a   Levi, Giovanni ^c   Olson, Eric N ^a   Srivastava, Deepak ^a,b   Wilkie, Thomas M ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

Craniofacial development; DHAND HAND2; Dl 3; Dl 6; EHAND HAND1; Endothelin; G protein; G q G 11; Neural crest; Pharyngeal arches

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DISTAL LESS HOMEOBOX PROTEINS; DISTAL-LESS HOMEOBOX PROTEINS; DLX6 PROTEIN, MOUSE; DNA BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HAND1 PROTEIN, MOUSE; HAND2 PROTEIN, MOUSE; HAND2 PROTEIN, ZEBRAFISH; HELIX LOOP HELIX PROTEIN, EHAND; HELIX-LOOP-HELIX PROTEIN, EHAND; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MSX1; ZEBRAFISH PROTEIN;

ARTICLE; CLEFT PALATE; CRANIOFACIAL DEVELOPMENT; DOWN REGULATION; EARDRUM; EMBRYO; GENE EXPRESSION; MANDIBLE HYPOPLASIA; MESENCHYME; MOUSE; NEURAL CREST; NONHUMAN; PHARYNX; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; BRANCHIAL ARCH; GENE EXPRESSION REGULATION; GENETICS; IN SITU HYBRIDIZATION; MESODERM; METABOLISM; MOUSE MUTANT; PRENATAL DEVELOPMENT;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BRANCHIAL REGION; DNA-BINDING PROTEINS; ENDOTHELIN-1; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HETEROTRIMERIC GTP-BINDING PROTEINS; HOMEODOMAIN PROTEINS; IN SITU HYBRIDIZATION; MESODERM; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MSX1 TRANSCRIPTION FACTOR; NEURAL CREST; PHENOTYPE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; ZEBRAFISH PROTEINS;

EID: 0037444047     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0012-1606(02)00097-0     Document Type: Article

References (27)

1. Boss V., Talpade D.J., Murphy T.J. Induction of NFAT-mediated transcription by Gq-coupled receptors in lymphoid and non-lymphoid cells. J. Biol. Chem. 271:1996;10429-10432.
2. Charité J., McFadden D.G., Merlo G., Levi G., Clouthier D.E., Yanagisawa M., Richardson J.A., Olson E.N. Role of Dlx6 in regulation of an endothelin-1-dependent, dHAND branchial arch enhancer. Genes Dev. 15:2001;3039-3049.
3. Clouthier D.E., Hosoda K., Richardson J.A., Williams S.C., Yanagisawa H., Kuwaki T., Kumada M., Hammer R.E., Yanagisawa M. Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. Development. 125:1998;813-824.
4. Clouthier D.E., Williams S.C., Yanagisawa H., Wieduwilt M., Richardson J.A., Yanagisawa M. Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. Dev. Biol. 217:2000;10-24.
5. Guillemot F. Vertebrate bHLH genes and the determination of neuronal fates. Exp. Cell Res. 253:1999;357-364.
6. A receptor antagonist blocks cardiac hypertrophy provoked by hemodynamic overload. Circulation. 89:1994;2198-2203.
7. Kurihara Y., Kurihara H., Oda H., Maemura K., Nagai R., Ishikawa T., Yazaki Y. Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1. J. Clin. Invest. 96:1995;293-300.
8. Kurihara Y., Kurihara H., Suzuki H., Kodama T., Maemura K., Nagai R., Oda H., Kuwaki T., Cao W.H., Kamada N., et al. Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1. Nature. 368:1994;703-710.
9. 2+ spike frequency can optimize gene expression. Nature. 392:1998;936-941.
10. McKinsey T., Zhang C.L., Olson E.N. MEF2: a calcium-dependent regulator of cell division, differentiation and death. Trends Biochem. Sci. 27:2002;40-47.
11. Molkentin J.D., Lu J.R., Antos C.L., Markham B., Richardson J., Robbins J., Grant S.R., Olson E.N. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell. 93:1998;215-228.
12. 2+ signaling complexes in secretory cells. Cell Calcium. 26:1999;173-180.
13. Nakagawa O., Nakagawa M., Richardson J.A., Olson E.N., Srivastava D. HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Dev. Biol. 216:1999;72-84.
14. q. Proc. Natl. Acad. Sci. USA. 94:1997;14089-14094.
15. 11 are concurrently activated by bombesin and vasopressin in Swiss 3T3 cells. FEBS Lett. 349:1994;201-204.
16. q-deficient mice. Nature. 389:1997;183-186.
17. 11-mutant mice. EMBO J. 17:1998;4304-4312.
18. Santagata S., Boggon T.J., Baird C.L., Gomez C.A., Zhao J., Shan W.S., Myszka D.G., Shapiro L. G-protein signaling through tubby proteins. Science. 292:2001;2041-2050.
19. Shi C.S., Kehrl J.H. PYK2 links Gqα and G13α signaling to NF-kappa B activation. J. Biol. Chem. 276:2001;31845-31850.
20. Smrcka A.V., Sternweis P.C. Regulation of purified subtypes of phosphatidylinositol-specific phospholipase Cβ by G protein α and βγ subunits. J. Biol. Chem. 268:1993;9667-9674.
21. Thomas T., Kurihara H., Yamagishi H., Kurihara Y., Yazaki Y., Olson E.N., Srivastava D. A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme. Development. 125:1998;3005-3014.
22. Tian J., Ma H.W., Bancroft C. Constitutively active Gqα stimulates prolactin promoter activity via a pathway involving Raf activity. Mol. Cell. Endocrinol. 112:1995;249-256.
23. 11 in cardiomyocytes. Nat. Med. 7:2001;1236-1240.
24. Wilkie T.M., Scherle P.A., Strathmann M.P., Slepak V.Z., Simon M.I. Characterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines. Proc. Natl. Acad. Sci. USA. 88:1991;10049-10053.
25. Xu D., Emoto N., Giaid A., Slaughter C., Kaw S., deWit D., Yanagisawa M. ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1. Cell. 78:1994;473-485.
26. Yamagishi H., Garg V., Matsuoka R., Thomas T., Srivastava D. A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects. Science. 283:1999;1158-1161.
27. Yanagisawa H., Yanagisawa M., Kapur R.P., Richardson J.A., Williams S.C., Clouthier D.E., de Wit D., Emoto N., Hammer R.E. Dual genetic pathways of endothelin- mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene. Development. 125:1998;825-836.