Indefinite islet protection from autoimmune destruction in nonobese diabetic mice by agarose microencapsulation without immunosuppression

Transplantation

Volumn 75, Issue 5, 2003, Pages 619-625

  Kobayashi, Tsunehiro ^a   Aomatsu, Yukio ^b   Iwata, Hiroo ^c   Kin, Tatsuya ^d   Kanehiro, Hiromichi ^a   Hisanaga, Michiyoshi ^a   Ko, Saiho ^a   Nagao, Mitsuo ^a   Nakajima, Yoshiyuki ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b Matsubara Municipal Hospital   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CAPILLARY; CELL DESTRUCTION; CELL GRANULE; CELL INFILTRATION; CELL ISOLATION; CELL PROTECTION; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOSUPPRESSIVE TREATMENT; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MEMBRANE PERMEABILITY; MICROENCAPSULATION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; RECURRENT DISEASE;

ANIMALS; AUTOIMMUNITY; CAPSULES; DIABETES MELLITUS, TYPE 1; GLUCOSE TOLERANCE TEST; GRAFT SURVIVAL; IMMUNOSUPPRESSION; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, INBRED NOD; OMENTUM; SEPHAROSE; TRANSPLANTATION, HETEROTOPIC;

EID: 0037444016     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000053749.36365.7E     Document Type: Article

References (30)

1. Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000; 343: 230.
2. Ryan EA, Lakey JR, Rajotte RV, et al. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes 2001; 50: 710.
3. Molano RD, Berney T, Li H, et al. Prolonged islet graft survival in NOD mice by blockade of the CD40-CD154 pathway of T-cell costimulation. Diabetes 2001; 50: 270.
4. Guo Z, Wu T, Kirchhof N, et al. Immunotherapy with nondepleting anti-CD4 monoclonal antibodies but not CD28 antagonists protects islet graft in spontaneously diabetic NOD mice from autoimmune destruction and allogeneic and xenogeneic graft rejection. Transplantation 2001; 71: 1656.
5. Adams AB, Shirasugi N, Durham MM, et al. Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates. Diabetes 2002; 51: 265.
6. Yasuda H, Nagata M, Arisawa K, et al. Local expression of Immunoregulatory IL-12p40 gene prolonged syngeneic islet graft survival in diabetic NOD mice. J Clin Invest 1998; 102: 1807.
7. Judge TA, Desai NM, Yang Z, et al. Utility of adenoviral-mediated Fas ligand gene transfer to modulate islet allograft survival. Transplantation 1998; 66: 426.
8. Sun Y, Ma X, Zhou D, et al. Normalization of diabetes in spontaneously diabetic cynomolgus monkeys by xenograft of microencapsulated porcine islets without immunosuppression. J Clin Invest 1996; 98: 1417.
9. Soon-Shiong P, Feldman E, Nelson R, et al. Successful reversal of spontaneous diabetes in dogs by intraperitoneal microencapsulated islets. Transplantation 1992; 54: 769.
10. Lim F, Sun AM. Microencapsulated islets as bioartificial endocrine pancreas. Science 1980; 210: 908.
11. Wang T, Lacik I, Brissova M, et al. An encapsulation system for the immunoisolation of pancreatic islets. Nat Biotechnol 1997; 15: 358.
12. O'Shea GM, Sun AM. Encapsulation of rat islets of Langerhans prolongs xenograft survival in diabetic mice. Diabetes 1986; 35: 943.
13. Weber CJ, Hagler MK, Chryssochoos JT, et al. CTLA4-Ig prolongs survival of microencapsulated neonatal porcine islet xenografts in diabetic NOD mice. Cell Transplant 1997; 6: 505.
14. Duvivier-Kali VF, Omer A, Parent RJ, et al. Complete protection of islets against allorejection and autoimmunity by a simple barium-alginate membrane. Diabetes 2001; 50: 1698.
15. Iwata H, Takagi T, Kobayashi K, et al. Strategy for developing microbeads applicable to islet xenotransplantation into a spontaneously diabetic NOD mice. J Biomed Mater Res 1994; 28: 1201.
16. Iwata H, Amemiya H, Matsuda T, et al. Evaluation of microencapsulated islets in agarose gel as biopancreas by studies of hormone secretion in culture and by xenotransplantation. Diabetes 1989; 38(suppl 1): 224.
17. Iwata H, Takagi T, Amemiya H, et al. Agarose for a bioartificial pancreas. J Biomed Mater Res 1992; 26: 967.
18. Iwata H, Amemiya H, Matsuda T, et al. Microencapsulation of Langerhans islets in agarose bioartificial pancreas. J Bioact Compat Polym 1988; 3: 356.
19. Tashiro H, Iwata H, Warnock GL, et al. Characterization and transplantation of agarose microencapsulated canine islets of Langerhans. Ann Transplant 1997; 2: 33.
20. Ohyama T, Nakajima Y, Kanehiro H, et al. Long-term normalization of diabetes by xenotransplantation of newly developed encapsulated pancreatic islets. Transplant Proc 1998; 30: 3433.
21. Tun T, Inoue K, Hayashi H, et al. A newly developed three-layer agarose microcapsule for a promising biohybrid artificial pancreas: Rat to mouse xenotransplantation. Cell Transplant 1996; 5(5 suppl 1): S59.
22. Kin T, Iwata H, Aomatsu Y, et al. Xenotransplantation of pig islets in diabetic dogs with use of a microcapsule composed of agarose and polystyrene sulfonic acid mixed gel. Pancreas 2002; 25: 94.
23. Lumelsky N, Blondel O, Laeng P, et al. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 2001; 292: 1389.
24. Ramiya VK, Maraist M, Arfors KE, et al. Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells. Nat Med 2000; 6: 278.
25. Gotoh M, Maki T, Kiyoizumi T, et al. An improved method for isolation of mouse pancreatic islets. Transplantation 1985; 40: 437.
26. Lacy PE, Kostianovsky M. Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 1967; 16: 35.
27. Iwata H, Murakami H, Ikada Y, et al. Control of complement activities for immunoisolation. Ann N Y Acad Sci 1999; 875: 7.
28. Kin T, Korbutt GS, Rajotte RV. The outcome of graft survival and function after syngeneic islet transplantation into the omental pouch. Acta Chir Austriaca 2001; 33(suppl): 63.
29. Ao Z, Matayoshi K, Lakey JRT, et al. Survival and function of purified islets in the omental pouch site of outbred dogs. Transplantation 1993; 56: 524.
30. Nishibe T, Satoh Y, Iwashiro N, et al. Expanded polytetrafluoroethylene grafts for portal vein replacement: Use of omentum wrap to promote graft healing. Surg Today 1997; 27: 149.