Identity and localization of advanced glycation end products on human β2-microglobulin using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Analytical Biochemistry

Volumn 314, Issue 2, 2003, Pages 322-325

  Cocklin, Ross R ^a   Zhang, Yinong ^a   O'Neill, Kalisha D ^a   Chen, Neal X ^a   Moe, Sharon M ^a   Bidasee, Keshore R ^b   Wang, Mu ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DESORPTION;

ADVANCED GLYCATION END PRODUCTS; BETA-2-MICROGLOBULIN; MATRIX-ASSISTED LASER DESORPTION/IONIZATION-TIME-OF-FLIGHT MASS SPECTROMETRY;

MASS SPECTROMETRY;

ADVANCED GLYCATION END PRODUCT; BETA 2 MICROGLOBULIN; IMIDAZOLONE A; IMIDAZOLONE B; N (CARBOXYMETHYL)LYSINE; PENTOSIDINE; PYRRALINE; UNCLASSIFIED DRUG;

ALKYLATION; AMYLOIDOSIS; ARTICLE; CARBOHYDRATE ANALYSIS; COMPUTER PROGRAM; DISEASE COURSE; GLYCATION; HEMODIALYSIS; HUMAN; ISOLATION PROCEDURE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METHODOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PURIFICATION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SPECTROSCOPY; STAINING; TECHNIQUE;

EID: 0037444012     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2697(02)00690-5     Document Type: Article

References (21)

1. Drueke T.B. Beta-2-microglobulin amyloidosis and renal bone disease. Miner. Electrolyte Metab. 17:1991;261-272.
2. Jadoul M., Garbar C., Noel H., Sennesael J., Vanholder R., Bernaert P., Rorive G., Hanique G., van Ypersele de Strihou C. Histological prevalence of beta 2-microglobulin amyloidosis in hemodialysis: a prospective post-mortem study. Kidney Int. 51:1997;1928-1932.
3. Ehlerding G., Schaeffer J., Drommer W., Miyata T., Koch K.M., Floege J. Alterations of synovial tissue and their potential role in the deposition of beta-2-microglobulin-associated amyloid. Nephrol. Dial. Transplant. 13:1998;1465-1475.
4. Argiles A., Mourad G., Kerr P.G., Garcia M., Collins B., Demaille J.G. Cells surrounding hemodialysis-associated amyloid deposits are mainly macrophages. Nephrol. Dial. Transplant. 9:1994;662-667.
5. Garcia-Garcia M., Argiles A., Gouin-Charnet A., Durfort M., Garcia-Valero J., Mourad G. Impaired lysosomal processing of beta-2-microglobulin by infiltrating macrophages in dialysis amyloidosis. Kidney Int. 55:1999;899-906.
6. Miyata T., Oda O., Inagi R., Iida Y., Araki N., Yamada N., Horiuchi S., Taniguchi N., Maeda K., Kinoshita T. Beta-2-microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis. J. Clin. Invest. 92:1993;1243-1252.
7. Vlassara H. Recent progress on the biologic and clinical significance of advanced glycosylation end products. J. Lab. Clin. Med. 124:1994;19-30.
8. Iida Y., Miyata T., Inagi R., Sugiyama S., Maeda K. Beta 2-microglobulin modified with advanced glycation end products induces interleukin-6 from human macrophages: role in the pathogenesis of hemodialysis-associated amyloidosis. Biochem. Biophys. Res. Commun. 201:1994;1235-1241.
9. Owen W.F. Jr., Hou F.F., Stuart R.O., Kay J., Boyce J., Chertow G.M., Schmidt A.M. Beta 2-microglobulin modified with advanced glycation end products modulates collagen synthesis by human fibroblasts. Kidney Int. 53:1998;1365-1373.
10. Yim M.B., Yim H.S., Lee C., Kang S.O., Chock P.B. Protein glycation: creation of catalytic sites for free radical generation. Ann. N Y Acad. Sci. 928:2001;48-53.
11. 2 -Microglobulin dialysis amyloid and its formation: role of 3-deoxyglucosone and advanced glycation end products Nephron. 76:1997;373-391.
12. Jadoul M., Ueda Y., Yasuda Y., Saito A., Robert A., Ishida N., Kurokawa K., van Ypersele de Strihou C., Miyata T. Influence of hemodialysis membrane type on pentosidine plasma level, a marker of "carbonyl stress" Kidney Int. 55:1999;2487-2492.
13. Pongor S., Ulrich P.C., Bencsath F.A., Cerami A. Aging of proteins: isolation and identification of a fluorescent chromophore from the reaction of polypeptides with glucose. Proc. Natl. Acad. Sci. USA. 81:1984;2684-2688.
14. Al-Abed Y., Bucala R. Structure of a synthetic glucose derived advanced glycation end product that is immunologically cross-reactive with its naturally occurring counterparts. Bioconjugate Chem. 11:2000;39-45.
15. Miyata T., Ueda Y., Shinzato T., Iida Y., Tanaka S., Kurokawa K., van Ypersele de Strihou C., Maeda K. Accumulation of albumin-linked and free-form pentosidine in the circulation of uremic patients with end-stage renal failure: renal implications in the pathophysiology of pentosidine. J. Am. Soc. Nephrol. 7:1996;1198-1206.
16. Ahmed N., Argirov O.K., Minhas H.S., Cordeiro C.A., Thornalley P.J. Assay of advanced glycation endproducts (AGEs): surveying AGEs by chromatographic assay with derivatization by 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and application to Nepsilon-carboxymethyl-lysine- and Nepsilon-(1-carboxyethyl)lysine-modified albumin. Biochem. J. 364:2002;1-14.
17. Ahmed N., Thornalley P.J. Chromatographic assay of glycation adducts in human serum albumin glycated in vitro by derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and intrinsic fluorescence. Biochem. J. 364:2002;15-24.
18. Miyata T., Inagi R., Wada Y., Ueda Y., Iida Y., Takahashi M., Taniguchi N., Maeda K. Glycation of human beta-2-microglobulin in patients with hemodialysis-associated amyloidosis: identification of the glycated sites. Biochemistry. 33:1994;12215-12221.
19. Chen N.X., O'Neill K.D., Niwa T., Moe S.M. Signal transduction of beta2m-induced expression of VCAM-1 and COX-2 in synovial fibroblasts. Kidney Int. 61:2002;414-424.
20. Jaradat M.I., Schnizlein-Bick C.T., Singh G.K., Moe S.M. Beta-2-microglobulin increases the expression of vascular cell adhesion molecule on human synovial fibroblasts. Kidney Int. 59:2001;1951-1959.
21. Moe S.M., Singh G.K., Bailey A.M. Beta-2-microglobulin induces MMP-1 but not TIMP-1 expression in human synovial fibroblasts. Kidney Int. 57:2000;2023-2034.