Alterations of synovial tissue and their potential role in the deposition of β2-microglobulin-associated amyloid

Nephrology Dialysis Transplantation

Volumn 13, Issue 6, 1998, Pages 1465-1475

  Ehlerding, Goetz ^a   Schaeffer, Juergen ^a   Drommer, Werner ^b   Miyata, Toshio ^c   Koch, Karl Martin ^a   Floege, Juergen ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^c TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

2 microglobulin; Advanced glycation end products; Amyloidosis; Dialysis; Immunohistology; Lymphocytes; Macrophages

Indexed keywords

ALPHA ACTIN; AMYLOID; BETA 2 MICROGLOBULIN; ADVANCED GLYCATION END PRODUCT; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; COLLAGEN TYPE 4; PROTEOHEPARAN SULFATE;

ADULT; AGED; AMYLOIDOSIS; ARTICLE; B LYMPHOCYTE; CELL INFILTRATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DIALYSIS; DISEASE PREDISPOSITION; FIBROBLAST; FOREIGN BODY REACTION; HEMODIALYSIS; HEMODIALYSIS PATIENT; HUMAN; IMMUNOHISTOLOGY; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNOVITIS; SYNOVIUM; T LYMPHOCYTE; UREMIA; BETA 2 MICROGLOBULIN ASSOCIATED AMYLOIDOSIS; CELL ACTIVATION; HUMAN TISSUE; MIDDLE AGED; PERITONEAL DIALYSIS; SYNOVIOCYTE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; AMYLOID; AMYLOIDOSIS; BETA 2-MICROGLOBULIN; CASE-CONTROL STUDIES; EXTRACELLULAR MATRIX; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LEUKOCYTES; MIDDLE AGED; PERITONEAL DIALYSIS; RENAL DIALYSIS; SYNOVIAL MEMBRANE; UREMIA;

EID: 0031748257     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/13.6.1465     Document Type: Article

References (52)

1. Assenat H, Calemard E, Charra B et al. Haemodialyse syndrome du canal carpien et substance amyloide. Presse Med 1980; 9: 1715
2. Gejyo F, Yamada T, Odani S et al. A new form of amyloid protein associated with chronic hemodialysis was identified as beta 2-microglobulin. Biochem Biophys Res Commun 1985; 129: 701-706
3. Koch KM. Dialysis-related amyloidosis (Clinical conference). Kidney Int 1992; 41: 1416-1429
4. Floege J, Ehlerding G. Beta-2-microglobulin-associated amyloidosis. Nephron 1996; 72: 9-26
5. Linke RP, Hampl H, Lobeck H et al. Lysine-specific cleavage of beta 2-microglobulin in amyloid deposits associated with hemodialysis. Kidney Int 1989; 36: 675-681
6. Odani H, Oyama R, Titani K, Ogawa H, Saito A. Purification and complete amino acid sequence of novel beta 2-microglobulin. Biochem Biophys Res Commun 1990; 168: 1223-1229
7. Miyata T, Oda O, Inagi R et al. Beta 2-microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis. J Clin Invest 1993; 92: 1243-1252
8. Aruga E, Ozasa H, Teraoka S, Ota K. Macromolecules that are colocalized with deposits of beta 2-microglobulin in hemodialysis-associated amyloidosis. Lab Invest 1993; 69: 223-230
9. Ohishi H, Skinner M, Sato AN et al. Glycosaminoglycans of the hemodialysis-associated carpal synovial amyloid and of amyloid-rich tissues and fibrils of heart, liver, and spleen. Clin Chem 1990; 36: 88-91
10. Homma N, Gejyo F, Isemura M, Arakawa M. Collagen-binding affinity of beta 2-microglobulin, a preprotein of hemodialysis-associated amyloidosis. Nephron 1989; 53: 37-40
11. Ogawa H, Saito A, Ono M. Inflammation as the possible cause of cystic radiolucencies in carpal bones of patients on hemodialysis. ASAIO Trans 1989; 35: 317-319
12. Sethi D, Morgan TC, Brown EA et al. Dialysis arthropathy: a clinical, biochemical, radiological and histological study of 36 patients. Q J Med 1990; 77: 1061-1082
13. Coggi G, Maiorano E, Braidotti P, Dell'Orto P, Viale G. Beta 2-microglobulin amyloidosis in synovial membranes: histopathology, immunocytochemistry and electron microscopy. In: Gejyo F, Brancaccio D, Bardin T, ed. Dialysis Amyloidosis. Wichtig Editore, Milan, 1989; 57-78
14. Theaker JM, Raine AE, Rainey AJ et al. Systemic amyloidosis of beta 2-microglobulin type: a complicatipn of long-term hasmodialysis. J Clin Pathol 1987; 40: 1247-1251
15. Argilés A, Mourad G, Kerr PG et al. Cells surrounding haemaodialysis-associated amyloid deposits are mainly macrophages. Nephrol Dial Transplant 1994; 9: 662-667
16. Sole M, Munoz Gomez J, Campistol JM. Role of amyloid in dialysis-related arthropathies. A morphological analysis of 23 cases. Virchows Arch [A] 1990; 417: 523-528
17. Nishi S, Ogino S, Maruyama Y et al. Electron-microscopic and immunohistochemical study of beta 2-microglobulin-related amyloidosis. Nephron 1990; 56: 357-363
18. Hampl H, Lobeck H, Bartel SS et al. Clinical, morphologic, biochemical, and immunohistochemical aspects of dialysis-associated amyloidosis. ASAIO Trans 1987; 33: 250-259
19. Honkanen E, Gronhagen Riska C, Teppo AM, Maury CP, Meri S. Acute-phase proteins during hemodialysis: correlations with serum interleukin-1 beta levels and different dialysis membranes. Nephron 1991; 57: 283-287
20. Heberlin A, Thu Nguyen A, Zingraff J, Urena P, Deschamps-Latscha B. Influence of uremia and hemodialysis on circulating interleukin-1 and tumor necrosis factor a. Kidney Int 1990; 37: 116-125
21. Haeffner-Cavaillon N, Cavaillon JM, Ciancioni C et al. In vivo induction of interleukin-1 during hemodialysis. Kidney Int 1989; 35: 1212-1218
22. Lonnemann G, Bingel M, Floege J et al. Detection of endotoxin-like interleukin-1 inducing activity during in vitro dialysis. Kidney Int 1988; 33: 29-35
23. Lonnemann G, Behme TC, Lenzner B et al. Permeability of dialyzer membranes to TNF-x-inducing substances derived from water bacteria. Kidney Int 1992; 42: 61-69
24. Mahiout A, Shaldon S, M. KK. Production of endotoxin and its related subfragments in contaminated bicarbonate dialysate (abstract). J Am Soc Nephrol 1991; 2: 337
25. Bingel M, Lonnemann G, Koch KM, Shaldon S. Enhancement of in vitro human interleukin-1 production by sodium acetate. Lancet 1987; 1: 14-16
26. Depierreux M, Goldman M, Fayt I et al. Osteoarticular amyloidosis associated with haemodialysis: an immunoultrastructural study. J Clin Pathol 1988; 41: 158-162
27. Elghethany MT, Saleem A. Methods for staining amyloid in tissue. Stain Technol 1988; 63: 201-212
28. Puchtler H, Sweat F, Levine M. On the binding of Congo red by amyloid. J Histochem Cytochem 1962; 10: 355-364
29. Athanasou NA. Synovial macrophages. Ann Rheum Dis 1995; 54: 392-394
30. Sappino AP, Schürch W, Gabbiani G. Biology of disease. Differential repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations. Lab Invest 1990; 63: 144-161
31. Campbell SE, Janicki JS, Weber KT. Temporal differences in fibroblast proliferation and phenotype expression in response to chronic administration of angiotensin II or aldosterone. J Mol Cell Cardiol 1995; 27: 1545-1560
32. Hewitson TD, Wu HL, Becker GJ. Interstitial myofibroblasts in experimental renal infection and scarring. Am J Nephrol 1995; 15: 411-417
33. Miyata T, Wada Y, Cai Z et al. Implication of an increased oxidative stress in the formation of advanced glycation end products in renal failure patients. Kidney Int (in press)
34. Bommer J, Waldherr R, Andrassy K, Ritz E. Carpal tunnel syndrome in dialysis patients. No evidence for amyloidosis (abstract). Kidney Int 1985; 28: 711
35. Ladefoged C, Merrild U, Jørgensen B. Amyloid deposits in surgically removed articular and periarticular tissue. Histopathology 1989; 15: 289-296
36. Mohr W. Amyloid deposits in periarticular tissues. Z Rheumatol 1976; 35: 412-417
37. Mitrovic D, Stankovic A, Quintero M, Rueckewaert A. Amyloid deposits in human knees and joints. Rheumatol Int 1985; 5: 83-89
38. Floege J, Schaffer J, Koch KM, Shaldon S. Dialysis related amyloidosis: a disease of chronic retention and inflammation? Kidney Int 1992; 38: S78-S85
39. Drueke TB. Beta-2-microglobulin amyloidosis and renal bone disease. Miner Electrolyte Metab 1991; 17: 261-272
40. Edwards JC. The nature and origins of synovium: experimental approaches to the study of synoviocyte differentiation. J Anal 1994; 184: 493-501
41. Zvaifler NJ. Macrophages and the synovial lining. Scand J Rheumatol Suppl 1995; 101: 67-75
42. Sole M, Cardesa A, Palacin A, Munoz Gomez J, Campistol JM. Morphological and immunohistochemical findings in dialysis-related amyloidosis An analysis of 16 cases. Appl Pathol 1989; 7: 350-360
43. Morita T, Suzuki M, Kamimura A, Hirasawa Y. Amyloidosis of a possible new type in patients receiving long-term hemodialysis. Arch Pathol Lab Med 1985; 109: 1029-1032
44. Campistol JM, Sole M, Bombi JA et al. In vitro spontaneous synthesis of beta 2-microglobulin amyloid fibrils in peripheral blood mononuclear cell culture. Am J Pathol 1992; 141: 241-247
45. Nakashima Y, Akizawa T, Nagai T, Koshikawa S. Role of uremic and endothelial factors in the development of beta 2-microglobulin amyloidosis. Kidney Int 1993; 41: S88-S95
46. Qu Z, Garcia CH, O'Rourke LM et al. Local proliferation of fibroblast-like synoviocytes contributes to synovial hyperplasia. Results of proliferating cell nuclear antigen/cyclin, c-myc, and nucleolar organizer region staining. Arthritis Rheum 1994; 37: 212-220
47. Assounga AG, Bascoul S, Canaud B et al. A study of beta 2-microglobulin skin deposits in dialyzed patients and healthy controls. Am J Kidney Dis 1990; 15: 556-561
48. Snow AD, Willmer J, Kisilevski R. Sulfated glycosaminoglycans: a common constituent of all amyloids? Lab invest 1987; 56: 120-123
49. Snow AD, Bramson R, Mar H, Wight TN, Kisilevsky R. A temporal and ultrastructural relationship between heparan sulfate proteoglycans and AA amyloid in experimental amyloidosis. J Histochem Cytochem 1991; 39: 1321-1330
50. Dodge GR, Boesler EW, Jimenez SA. Expression of the basement membrane heparan sulfate proteoglycan (perlecan) in human synovium and in cultured human synovial cells. Lab Invest 1995; 73: 649-657
51. Miyata T, Ueda Y, Shinzato T et al. Accumulation of albumin-linked and free-form pentosidine in the circulation of uremic patients with end-stage renal failure: renal implications in the pathophysiology of pentosidine. J Am Soc Nephrol 1996; 7: 1198-1206
52. 2-microglobulin-containing amyloid fibrils in patients with dialysis related amyloidosis. Proc Natl Acad Sci USA 1996; 93: 2353-2358