Uroporphyrin accumulation in hepatoma cells expressing human or mouse CYP1A2: Relation to the role of CYP1A2 in human porphyria cutanea tarda

Biochemical Pharmacology

Volumn 65, Issue 4, 2003, Pages 545-550

  Nichols, Ralph C ^a,b   Cooper, Sandra ^a,b   Trask, Heidi W ^a,b   Gorman, Nadia ^a,b   Dalton, Timothy P ^c   Nebert, Daniel W ^c   Sinclair, Jacqueline F ^a,b   Sinclair, Peter R ^a,b  

^a VA MEDICAL CENTER   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

5 Aminolevulinic acid; CYP1A2; Porphyria cutanea tarda; Uroporphyrin; Uroporphyrinogen oxidation

Indexed keywords

AMINOLEVULINIC ACID; CYTOCHROME P450 1A2; ENZYME; METHOXYRESORUFIN DEMETHYLASE; UNCLASSIFIED DRUG; UROPORPHYRIN;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CATALYSIS; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; HEPATOMA CELL; HUMAN; HUMAN CELL; IMMUNODETECTION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PORPHYRIA CUTANEA TARDA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

AMINOLEVULINIC ACID; ANIMALS; CARCINOMA, HEPATOCELLULAR; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; IMMUNOBLOTTING; MICE; OXIDOREDUCTASES; PORPHYRIA CUTANEA TARDA; TRANSFECTION; TUMOR CELLS, CULTURED; UROPORPHYRINS;

EID: 0037441339     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)01550-2     Document Type: Article

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