Gonadal steroids exert facilitating and 'buffering' effects on glucocorticoid-mediated transcriptional regulation of corticotropin-releasing hormone and corticosteroid receptor genes in rat brain

Journal of Neuroscience

Volumn 16, Issue 21, 1996, Pages 7077-7084

  Patchev, Vladimir K ^a   Almeida, Osborne F X ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

corticosteroid receptors; corticotropin releasing hormone (CRH); gene expression; hippocampus; hypothalamus; sex steroids

Indexed keywords

ANDROSTANOLONE; CORTICOSTEROID RECEPTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR; ESTRADIOL; PROGESTERONE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GONADECTOMY; HIPPOCAMPUS; HORMONAL REGULATION; HORMONE DETERMINATION; HORMONE RECEPTOR INTERACTION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SUBCUTANEOUS DRUG ADMINISTRATION; THALAMUS MIDLINE NUCLEUS; TRANSCRIPTION REGULATION;

EID: 0029961403     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-21-07077.1996     Document Type: Article

References (47)

1. Ahima RS, Lawson ANL, Osei SYS, Harlan RE (1992) Sexual dimorphism in regulation of type II corticosteroid receptor immunoreactivity in the rat hippocampus. Endocrinology 131:1409-1416.
2. Almeida OFX, Hassan AHS, Harbuz MS, Linton EA, Lightman SL (1992) Hypothalamic corticotropin-releasing hormone and opioid peptide neurons: functional changes after adrenalectomy and/or castration. Brain Res 571:189-198.
3. Arriza JL, Simerly WB, Swanson LW, Evans RM (1988) The neuronal mineralocorticoid receptor as a mediator of the glucocorticoid response. Neuron 1:887-900.
4. Bingaman EW, Magnuson DJ, Gray TS, Handa RJ (1994) Androgen inhibits the increases in hypothalamic corticotropin-releasing hormone (CRH) and CRH-immunoreactivity following gonadectomy. Neuroendocrinology 59:228-234.
5. Bohler Jr HCL, Zoeller RT, King JC, Rubin BS, Merriam GR (1990) Corticotropin-releasing hormone mRNA is elevated on the afternoon of proestrus in the parvocellular paraventricular nuclei of the female rat. Mol Brain Res 8:259-262.
6. Brady LS, Smith M, Gold PW, Herkenham M (1990) Altered expression of hypothalamic neuropeptide mRNA in food-restricted and food-deprived rats. Neuroendocrinology 52:441-447.
7. Burgess LH, Handa RJ (1992) Chronic estrogen-induced alterations in adrenocorticotropin and corticosterone secretion, and glucocorticoid receptor-mediated functions in female rats. Endocrinology 131:1261-1269.
8. Carey MP, Deterd CH, de Koning J, Heimerhorst F, de Kloet ER (1995) The influence of ovarian steroids on hypothalamic-pituitary-adrenal regulation in the female rat. J Endocrinol 144:311-321.
9. Carson-Jurica MA, Schrader WT, O'Malley BW (1991) Steroid receptor family: structure and functions. Endocr Rev 11:201-220.
10. Castrén M, Patchev VK, Almeida OFX, Holsboer F, Trapp T, Castrén E (1995) Regulation of rat mineralocorticoid receptor expression in neurons by progesterone. Endocrinology 136:3800-3806.
11. Critchlow V, Liebelt RA, Bar-Sela M, Mountcastle W, Lipscomb HS (1963) Sex difference in resting pituitary-adrenal function in the rat. Am J Physiol 205:807-815.
12. Dallman MF, Akana SF, Scribner KA, Bradbury MJ, Walker C-D, Strack AM, Cascio CS (1992) Stress, feedback and facilitation in the hypothalamo-pituitary-adrenal axis. J Neuroendocrinol 4:517-526.
13. de Kloet ER, Oitzl MS, Joëls M (1993) Functional implications of brain corticosteroid receptor diversity. Cell Mol Neurobiol 13:433-455.
14. Gould E, Wooley CS, McEwen BS (1991) The hippocampal formation: morphological changes induced by thyroid, gonadal and adrenal hormones. Psychoneuroendocrinology 16:67-84.
15. Goy RW, McEwen BS (1980) Sexual differentiation of the brain. Cambridge: MIT.
16. Haas DA, George SR (1988) Gonadal regulation of corticotropin-releasing factor immunoreactivity in hypothalamus. Brain Res Bull 20:361-367.
17. Hagihara K, Hirata S, Osada T, Hirai M, Kato J (1992) Distribution of cells containing progesterone receptor mRNA in the female rat di- and telencephalon: an in situ hybridization study. Mol Brain Res 14:239-249.
18. Handa RJ, Nunley KM, Lorens SA, Louie JP, McGivern RF, Bollnow MR (1994) Androgen regulation of adrenocorticotropin and corticosterone secretion in the male rat following novelty and footshock stressors. Physiol Behav 55:117-124.
19. Herman JP (1993) Regulation of adrenocorticosteroid receptor mRNA expression in the central nervous system. Cell Mol Neurobiol 13:349-371.
20. Jingami H, Mizuno N, Takahashi S, Shibahara S, Furutani Y, Imura H, Numa S (1985) Cloning and sequence analysis of cDNA for rat corticotropin-releasing factor precursor. FEBS Lett 191:63-66.
21. Keller-Wood M, Silbiger J, Wood CE (1988) Progesterone attenuates the inhibition of adrenocorticotropin responses by cortisol in nonpregnant ewes. Endocrinology 123:647-651.
22. Kessler RC, McGonagle KA, Swartz M, Blazer DG, Nelson CB (1993) Sex and depression in the National Comorbidity Survey. I. Lifetime prevalence, chronicity and recurrence. J Affect Disord 29:85-96.
23. Kitay JI (1961) Sex differences in adrenal cortical secretion in the rat. Endocrinology 68:818-824.
24. Loy R, Gerlach JL, McEwen BS (1988) Autoradiographic localization of estradiol-binding neurons in the rat hippocampal formation and entorhinal cortex. Dev Brain Res 39:245-251.
25. Madeira MD, Lieberman AR (1995) Sexual dimorphism in the mammalian limbic system. Prog Neurobiol 45:275-333.
26. Matsumoto A (1991) Synaptogenic action of sex steroids in developing and adult neuroendocrine brain. Psychoneuroendocrinology 16:25-40.
27. McEwen BS, de Kloet ER, Rostene W (1986) Adrenal steroid receptors and actions in the nervous system. Physiol Rev 66:1121-1188.
28. Miesfeld R, Rusconi S, Godowski PJ, Maler BA, Okret S, Wikström A-K, Gustafsson J-Å (1986) Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA. Cell 46:389-399.
29. Miranda RC, Sohrabji F, Toran-Allerand CD (1993) Presumptive estrogen target neurons express mRNAs for both neurotrophins and neurotrophin receptors: a basis for potential developmental interactions of estrogen with the neurotrophins. Mol Cell Neurosci 4:510-525.
30. Patchev VK, Brady LS, Karl M, Chrousos GP (1994) Regulation of HSP90 and corticosteroid receptor mRNA by corticosterone levels in vivo. Mol Cell Endocrinol 103:57-64.
31. Patchev VK, Hayashi S, Orikasa C, Almeida OFX (1995) Implications of estrogen-dependent brain organization for gender differences in hypothalamo-pituitary-adrenal regulation. FASEB J 9:419-423.
32. Peiffer A, Lapointe B, Barden N (1991) Hormonal regulation of type II glucocorticoid receptor messenger ribonucleic acid in rat brain. Endocrinology 129:2166-2174.
33. Pelletier G, Liao N, Follea N, Govindan MV (1988) Mapping of estrogen receptor-producing cells in the rat brain by in situ hybridization. Neurosci Lett 94:23-28,
34. Sapolsky RM, Plotsky PM (1990) Hypercorticalism and its possible neural bases. Biol Psychiatry 27:937-952.
35. Sawchenko PE (1987) Adrenalectomy-induced enhancement of CRF and vasopressin immunoreactivity in parvocellular neurosecretory neurons: anatomic, peptide, and steroid specificity. J Neurosci 7:1093-1106.
36. Simerly RB, Chang C, Muramatsu M, Swanson LW (1990) Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study. J Comp Neurol 294:76-95.
37. Spencer RL, Miller AH, Stein M, McEwen BS (1991) Corticosterone regulation of type I and type II adrenal steroid receptors in brain, pituitary, and immune tissue. Brain Res 549:236-246.
38. Svec F (1988) Differences in the interaction of RU 486 and ketoconazole with the second binding site of the glucocorticoid receptor. Endocrinology 123:1902-1906.
39. Swanson LW, Simmons DM (1989) Differential steroid hormone and neural influences on peptide mRNA levels in CRH cells of the paraventricular nucleus: a hybridization histochemical study in the rat. J Comp Neurol 285:413-435.
40. Trapp T, Rupprecht R, Castrén M, Reul JMHM, Holsboer F (1994) Heterodimerization between mineralocorticoid and glucocorticoid receptor: a new principle of glucocorticoid action in the CNS. Neuron 13:1-20.
41. Turner BA, Weawer DA (1985) Sexual dimorphism of glucocorticoid binding in rat brain. Brain Res 343:16-23.
42. Vamvakopoulos NC, Chrousos GP (1993) Evidence of direct estrogenic regulation of human corticotropin-releasing hormone gene expression: potential implications for the sexual dimorphism of the stress response and immune/inflammatory reaction. J Clin Invest 92:1896-1902.
43. Viau V, Meaney MJ (1991) Variations in the hypothalamic-pituitary-adrenal response to stress during the estrous cycle in the rat. Endocrinology 129:2503-2511.
44. Wahli W, Martinez E (1991) Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression. FASEB J 5:2243-2249.
45. Weissman MM, Bland R, Joyce PR, Newman S, Wells EJ, Wittchen H-U (1993) Sex differences in rates of depression: cross-national perspectives. J Affect Disord 29:77-84.
46. Whitfield Jr HJ, Brady LS, Smith MA, Mamalaki E, Fox R, Herkenham M (1990) Optimization of cRNA probe in situ hybridization methodology for localization of glucocorticoid receptor mRNA in rat brain: a detailed protocol. Cell Mol Neurobiol 10:145-157.
47. Young EA (1995) Glucocorticoid cascade hypothesis revisited: role of gonadal steroids. Depression 3:20-27.