Production of recombinant xenotransplantation antigen in Escherichia coli

Biochemical and Biophysical Research Communications

Volumn 302, Issue 3, 2003, Pages 620-624

  Bettler, Emmanuel ^a,d   Imberty, Anne ^a   Priem, Bernard ^a   Chazalet, Valérie ^a   Heyraud, Alain ^a   Joziasse, David H ^b   Geremia, Roberto A ^c  

^a CENTRE DE RECHERCHES SUR LES MACROMOLÉCULES VÉGÉTALES CERMAV CNRS   (France)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIV GRENOBLE ALPES   (France)

^d RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Carbohydrate biotechnology; Glycosyltransferases; Oligosaccharide production; Xenotransplantation antigen

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL POLYSACCHARIDE; CHITIN; EPITOPE; GALACTOSYLTRANSFERASE; RECOMBINANT ANTIGEN; TRANSPLANTATION ANTIGEN;

ARTICLE; BACTERIAL STRAIN; GRAFT REJECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNTHESIS; XENOGRAFT;

BOVINAE; ESCHERICHIA COLI; SUIDAE;

EID: 0037436833     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00227-4     Document Type: Article

References (24)

1. Fang J., Li J., Chen X., Zhang Y., Wang J., Guo Z., Zhang W., Yu K., Brew K., Wang P.G. Highly efficient chemoenzymatic synthesis of α-galactosyl epitopes with a recombinant α(1-3)-galactosyltransferase. J. Am. Chem. Soc. 120:1998;6635-6638.
2. Koizumi S., Endo T., Tabata K., Ozaki A. Large-scale production of UDP-galactose and globotriose by coupling metabolically engineered bacteria. Nat. Biotechnol. 16:1998;847-850.
3. Endo T., Koizumi S., Tabata K., Kakita S., Ozaki A. Large-scale production of N-acetyllactosamine through bacterial coupling. Carbohydr. Res. 316:1999;179-183.
4. Endo T., Koizumi S., Tabata K., Ozaki A. Large-scale production of CMP-NeuAc and sialylated oligosaccharides through bacterial coupling. Appl. Microbiol. Biotechnol. 53:2000;257-261.
5. Samain E., Drouillard S., Heyraud A., Driguez H., Geremia R.A. Gram-scale synthesis of recombinant chitooligosaccharides in Escherichia coli. Carbohydr. Res. 302:1997;35-42.
6. Samain E., Chazalet V., Geremia R.A. Production of O-acetylated and sulfated chitooligosaccharides by recombinant Escherichia coli strains harboring different combinations of nod genes. J. Biotechnol. 72:1999;33-47.
7. Galili U., Shohet S.B., Kobrin E., Stults C.L., Macher B.A. Man, apes, and Old World monkeys differ from other mammals in the expression of α-galactosyl epitopes on nucleated cells. J. Biol. Chem. 263:1988;17755-17762.
8. Galili U. Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: a major obstacle for xenotransplantation in humans [see comments]. Immunol. Today. 14:1993;480-482.
9. Cooper D.K., Gollackner B., Sachs D.H. Will the pig solve the transplantation backlog? Annu. Rev. Med. 53:2002;133-147.
10. Janczuk A., Li J., Zhang W., Chen X., Chen Y., Fang J., Wang J., Wang P.G. α-Gal oligosaccharides: chemistry and potential biomedical application. Curr. Med. Chem. 6:1999;155-164.
11. Vic G., Tran C.H., Scigelova M., Crout D.H.G. Glycosidase-catalysed synthesis of oligosaccharides: a one step synthesis of lactosamine and of the linear B type 2 trisaccharide α-D-Gal-(1-3)-β-D-Gal-(1-4)-β-D-GlcNAcSEt involved in the hyperacute rejection response in xenotransplantation from pigs to man and as the specific receptor for toxin A from Clostridium difficile. Chem. Commun. 1997;169-170.
12. Chen X., Zhang J., Kowal P., Liu Z., Andreana P.R., Lu Y., Wang P.G. Transferring a biosynthetic cycle into a productive Escherichia coli strain: large-scale synthesis of galactosides. J. Am. Chem. Soc. 123:2001;8866-8867.
13. Chen X., Liu Z., Zhang J., Zhang W., Kowal P., Wang P.G. Reassembled biosynthetic pathway for large-scale carbohydrate synthesis: α-gal epitope producing SUPERBUG. Chem. BioChem. 3:2002;47-53.
14. Geremia R.A., Mergaert P., Geelen D., Van Montagu M., Holsters M. The NodC protein of Azorhizobium caulinodans is a N-acetylglucosaminyl transferase. Proc. Natl. Acad. Sci. USA. 91:1994;2669-2673.
15. Bettler E., Samain E., Chazalet V., Bosso C., Heyraud A., Joziasse D.H., Wakarchuk W.W., Imberty A., Geremia A.R. The living factory: in vivo production of N-acetyllactosamine containing carbohydrates in E. coli. Glycoconj. J. 16:1999;205-212.
16. Joziasse D.H., Shaper J.H., Van den Eijnden D.H., Van Tunen A.J., Shaper N.L. Bovine α1-3-galactosyltransferase: isolation and characterization of a cDNA clone. Identification of homologous sequences in human genomic DNA. J. Biol. Chem. 264:1989;14290-14297.
17. Kovach M.E., Phillips R.W., Elzer P.H., Roop R.M. 2nd, Peterson K.M. pBBR1MCS: a broad-host-range cloning vector. Biotechniques. 16:1994;800-802.
18. Hamilton C.M., Aldea M., Washburn B.K., Babitzke P., Kushner S.R. New method for generating deletions and gene replacements in Escherichia coli. J. Bacteriol. 171:1989;4617-4622.
19. Geremia R.A., Roux M., Ferreiro D.U., Dauphin-Dubois R., Lellouch A.C., Ielpi L. Expression and biochemical characterisation of recombinant AceA, a bacterial α-mannosyltransferase. Mol. Gen. Genet. 261:1999;933-940.
20. Geremia R.A., Samain E. Production of heterologous oligosaccharides by recombinant bacteria (recombinant oligosaccharides). Ernst B., Sinaÿ P., Hart G. Carbohydrates in Chemistry and Biology. 2000;845-860 Wiley-VCH, Weinheim.
21. Kren V., Dvorakova J., Gambert U., Sedmera P., Havlicek V., Thiem J., Bezouska K. β-Glucosylation of chitooligomers by galactosyltransferase. Carbohydr. Res. 305:1997;517-523.
22. Saito T., Itoh T., Adachi S. Chemical structure of three neutral trisaccharides isolated in free form from bovine colostrum. Carbohydr. Res. 165:1987;43-51.
23. Li J., Ksebati M.B., Zhang W., Guo Z., Wang J., Yu L., Fang J., Wang P.G. Conformational analysis of an α-galactosyl trisaccharide epitope involved in hyperacute rejection upon xenotransplantation. Carbohydr. Res. 315:1999;76-88.
24. Chen X., Liu Z., Wang J., Fang J., Fan H., Wang P.G. Changing the donor cofactor of bovine α1,3-galactosyltransferase by fusion with UDP-galactose 4-epimerase. More efficient biocatalysis for synthesis of α-Gal epitopes. J. Biol. Chem. 275:2000;31594-31600.