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Volumn 107, Issue 6, 2003, Pages 1466-1472

Significance of charge regulation in the analysis of protein charge ladders

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE CARBONIC ANHYDRASE; CAPILLARY ELECTROPHORESIS; CHARGE REGULATION; ELECTROSTATIC POTENTIAL; HUCKEL THEORY; PROTEIN CHARGE LADDERS;

EID: 0037434749     PISSN: 10895647     EISSN: None     Source Type: Journal    
DOI: 10.1021/jp027066w     Document Type: Article
Times cited : (34)

References (36)
  • 17
    • 0013447389 scopus 로고    scopus 로고
    • note
    • 2 group is 98.8% protonated.
  • 18
    • 0013443723 scopus 로고    scopus 로고
    • note
    • The double layer is a diffuse cloud of ions carrying the charge opposite to that of the charged particle.
  • 20
    • 0013456257 scopus 로고    scopus 로고
    • note
    • The variable x is a dummy variable used to define the integral.
  • 22
    • 0013456258 scopus 로고    scopus 로고
    • note
    • At pH 8.4 in Tris-Gly buffer, the electrostatic potential of the first four rungs of the BCAII ladder is below |25 mV|. The electrostatic potential of the later rungs lies above |25 mV|. In general, in other experimental conditions presented here, the potential of first six rungs in below |25 mV|.
  • 27
    • 0013356222 scopus 로고    scopus 로고
    • note
    • a values.
  • 28
    • 0004140795 scopus 로고
    • W. H. Freeman and Co: New York
    • Average partial specific volume is calculated from the values of partial specific volumes of 20 proteins given in Creighton, T. E. Proteins. Structure and Molecular Properties; W. H. Freeman and Co: New York, 1993; p 266.
    • (1993) Proteins. Structure and Molecular Properties , pp. 266
    • Creighton, T.E.1
  • 31
    • 0013399805 scopus 로고    scopus 로고
    • note
    • The two charges, located on the protein, interact through the low dielectric core of the protein as well as through the high dielectric solvent medium. The screening of charge-charge interactions will, therefore, be less than for small, separate ions in solution.
  • 32
    • 0034669239 scopus 로고    scopus 로고
    • note
    • max between our and Zydney's calculations comes from the number of His and N-terminal acetylations used. We thank Prof. Zydney for helping us determine the reasons for this discrepancy.
    • (2000) Anal. Chem. , vol.72 , pp. 5714-5717
    • Menon, M.K.1    Zydney, A.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.