Enantiospecific synthesis of carbapentostatins

Journal of Organic Chemistry

Volumn 68, Issue 1, 2003, Pages 109-114

  Ho, Jonathan Z ^a   Mohareb, Rafat M ^a,b   Ahn, Jin Hee ^a   Sim, Tae Bo ^a   Rapoport, Henry ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAPENTOSTATINS;

DEHYDRATION; OXIDATION; REDUCTION; SYNTHESIS (CHEMICAL);

AROMATIC COMPOUNDS;

4 AMINO 1 CYCLOPENTENEMETHANOL DERIVATIVE; ALCOHOL; ALDEHYDE; AMINOCYCLITOL; AMINOCYCLOPENTANOL; ASPARTIC ACID; BORANE DERIVATIVE; CARBAPENTOSTATIN; ESTER DERIVATIVE; METHANOL DERIVATIVE; PENTANOL; STATIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; DEHYDRATION; ENANTIOMER; HYDROBORATION; REDUCTION; STEREOSPECIFICITY; SWERN OXIDATION; SYNTHESIS;

COFORMYCIN; COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLIZATION; MOLECULAR STRUCTURE; PENTOSTATIN; STEREOISOMERISM;

EID: 0037427985     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo020612x     Document Type: Article

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26. 3 using TMS as an internal standard. Optical rotations were measured at 25°C. Melting points are uncorrected. Column chromatography was performed using 230-400 mesh silica gel.