The in vivo but not the in vitro am3 revertant frequencies increase linearly with increased ethylnitrosourea doses in spleen of mice transgenic for phiX174 am3, cs70 using the single burst assay

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 534, Issue 1-2, 2003, Pages 1-13

  Weaver, Robert P ^a   Malling, Heinrich V ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Base substitution; Ethylnitrosourea dose response; In vivo and in vitro mutations; O2 ET dT lesions; PhiX174 transgenic mice; Single burst assay; Spleen

Indexed keywords

ETHYLNITROSOUREA; IMMUNOFERON;

ANIMAL TISSUE; ARTICLE; ASSAY; BASE MISPAIRING; CODON; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; REVERTANT; SEQUENCE ANALYSIS; SPLEEN; TRANSGENIC MOUSE; VALIDATION PROCESS;

ANIMALS; BACTERIOPHAGE PHI X 174; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHYLNITROSOUREA; GENE FREQUENCY; LINEAR MODELS; MALE; MICE; MICE, TRANSGENIC; MUTAGENICITY TESTS; MUTAGENS; MUTATION; ORGAN SIZE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPLEEN;

ANIMALIA; MUS MUSCULUS;

EID: 0037427855     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(02)00242-5     Document Type: Article

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