Suppression of lung metastasis of mouse Lewis lung cancer P29 with transfection of the ganglioside GM2/GD2 synthase gene

International Journal of Cancer

Volumn 103, Issue 2, 2003, Pages 169-176

  Chen, Ho Hsiang ^a   Fukumoto, Satoshi ^a   Furukawa, Keiko ^a   Nakao, Akimasa ^a   Akiyama, Seiji ^a   Urano, Takeshi ^a   Furukawa, Koichi ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adhesion; Ganglioside; Glycosyltransferase; Metastasis; Transfection

Indexed keywords

COMPLEMENTARY DNA; FOCAL ADHESION KINASE; GANGLIOSIDE; GANGLIOSIDE GD2; GANGLIOSIDE GM2; HERMES ANTIGEN;

ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LEWIS CARCINOMA; LUNG CANCER; LUNG METASTASIS; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

ANIMALS; CARCINOMA, LEWIS LUNG; CELL MEMBRANE; DNA, COMPLEMENTARY; FEMALE; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; G(M2) GANGLIOSIDE; GANGLIOSIDES; INTEGRINS; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; N-ACETYLGALACTOSAMINYLTRANSFERASES; NEOPLASM TRANSPLANTATION; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; SKIN NEOPLASMS; TRANSFECTION; TUMOR CELLS, CULTURED; TYROSINE; VITRONECTIN;

EID: 0037427804     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10797     Document Type: Article

References (44)

1. Hakomori S. Glycosphingolipids in cellular interaction, differentiation, and oncogenesis. Annu Rev Biochem 1981;50:733-64.
2. Burns GF, Lucas CM, Krissansen GW, Werkmeister JA, Scanlon DB, Simpson RJ, Vadas MA. Synergism between membrane gangliosides and Arg-Gly-Asp-directed glycoprotein receptors in attachment to matrix proteins by melanoma cells. J Cell Biol 1988;107:1225-30.
3. 3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins. J Cell Biol 1986;102:688-96.
4. 2. Prog Clin Biol Res 1989;288:3-24.
5. Mugnai G, Lewandowska K, Choi HU, Rosenberg LC, Culp LA. Ganglioside-dependent adhesion events of human neuroblastoma cells regulated by the RGDS-dependent fibronectin receptor and proteoglycans. Exp Cell Res 1988;175:229-47.
6. Rauvala H. Neurite outgrowth of neuroblastoma cells: Dependence on adhesion surface-cell surface interactions. J Cell Biol 1984;98:1010-6.
7. Merzak A, Koochekpour S, Pilkington GJ. Adhesion of human glioma cell lines to fibronectin, laminin, vitronectin and collagen 1 is modulated by gangliosides in vitro. Cell Adhes Commun 1995;3:27-43.
8. 1α highly expressed in poorly metastatic FBJ-S1 cells. Biochem Biophys Res Commun 1997;231:340-3.
9. 1α functions in the adhesion of metastatic tumor cells to endothelial cells of the target tissue. Cancer Res 1997;57:1882-8.
10. Saiki I. Cell adhesion molecules and cancer metastasis. Jpn J Pharmacol 1997;75:215-42.
11. Svennerholm L. Chromatographic separation of human brain gangliosides. J Neurochem 1963;10:455-63.
12. Zhang S, Cordon-Cardo C, Zhang HS, Reuter VE, Adluri S, Hamilton WB, Lloyd KO, Livingston PO. Selection of tumor antigens as targets for immune attack using immunohistochemistry: I. Focus on gangliosides. Int J Cancer 1997;73:42-9.
13. 2 synthase mRNA in human gastrointestinal cancer. Cancer 1995;75:1273-80.
14. 2 gangliosides in human cancer cell lines. Cancer Res 1993;53:5395-400.
15. Carubia JM, Yu RK, Macala LJ, Kirkwood JM, Varga JM. Gangliosides of normal and neoplastic human melanocytes. Biochem Biophys Res Commun 1984;120:500-4.
16. Dippold WG, Lloyd KO, Li LT, Ikeda H, Oettgen HF, Old LJ. Cell surface antigens of human malignant melanoma: Definition of six antigenic systems with mouse monoclonal antibodies. Proc Natl Acad Sci USA 1980;77:6114-8.
17. Elder DE, Rodeck U, Thurin J, Cardillo F, Clark WH, Stewart R, Herlyn M. Antigenic profile of tumor progression stages in human melanocytic nevi and melanomas. Cancer Res 1989:49:5091-6.
18. 2 ganglioside biosynthesis is a distinct biochemical event in human melanoma tumor progression. FEBS Lett 1986;208:17-22.
19. Kuo CT, Bostick PJ, Irie RF, Morton DL, Conrad AJ, Hoon DS. Assessment of messenger RNA of β1→4-N-acetylgalactosaminyl-transferase as a molecular marker for metastatic melanoma. Clin Cancer Res 1998;4:411-8.
20. 2 gangliosides. J Biol Chem 1992;267:12082-9.
21. 2 monoclonal antibody. Proc Natl Acad Sci USA 1994;91:10455-9.
22. Fukumoto S, Miyazaki H, Goto G, Urano T, Furukawa K, Furukawa K. Expression cloning of mouse cDNA of CMP-NeuAc:lactosylceramide α2,3-sialyltransferase, an enzyme that initiates the synthesis of gangliosides. J Biol Chem 1999;274:9271-6.
23. 3 synthase) gene in human cancer cell lines: High level expression in melanomas and up-regulation in activated T lymphocytes. Glycoconj J 1995;12:894-900.
24. tax. Proc Natl Acad Sci USA 1993;90:1972-6.
25. Takasu M, Tada Y, Wang JO, Tagawa M, Takenaga K. Resistance to apoptosis induced by microenvironmental stresses is correlated with metastatic potential in Lewis lung carcinoma. Clin Exp Metastasis 1999;17:409-16.
26. Takenaga K. Characterization of low- and high-metastatic clones isolated from a Lewis lung carcinoma. Jpn J Cancer Res 1984;75:61-71.
27. 2 in small cell lung cancer cell lines: Enhancement of cell proliferation and mediation of apoptosis. Cancer Res 2001;61:4244-52.
28. Portoukalian J, Zwingelstein G, Dore JF, Bourgoin JJ. Studies of a ganglioside fraction extracted from human malignant melanoma. Biochimie 1976;58:1285-7.
29. 3 synthase) gene in adult T-cell leukemia cells unrelated to the gene expression of human T-lymphotropic virus type I. Cancer Res 1996;56:2844-8.
30. 2, a relevant target antigen on small cell lung carcinoma for monoclonal antibody-mediated cytolysis. Cancer Res 1986;46:5112-8.
31. Tsurifune T, Ito T, Li XJ, Yamashiro S, Okada M, Kanematsu T, Shiku H, Furukawa K. Alteration of tumor phenotypes of B16 melanoma after genetic remodeling of the ganglioside profile. Int J Oncol 2000;17:159-65.
32. Clark EA, Brugge JS. Integrins and signal transduction pathways: The road taken. Science 1995;268:233-9.
33. Parsons JT, Martin KH, Slack JK, Taylor JM, Weed SA. Focal adhesion kinase: A regulator of focal adhesion dynamics and cell movement. Oncogene 2000;19:5606-13.
34. Hakomori S. Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism. Cancer Res 1996;56:5309-18.
35. Kleinman HK, Martin GR, Fishman PH. Ganglioside inhibition of fibronectin-mediated cell adhesion to collagen. Proc Natl Acad Sci USA 1979;76:3367-71.
36. Mugnai G, Lewandowska K, Culp LA. Multiple and alternative adhesive responses on defined substrata of an immortalized dorsal root neuron hybrid cell line. Eur J Cell Biol 1988;46:352-61.
37. Zheng M, Fang H, Tsuruoka T, Tsuji T, Sasaki T, Hakomori S. Regulatory role of GM3 ganglioside in alpha5beta1 integrin receptor for fibronectin-mediated adhesion of FUA169 cells. J Biol Chem 1993;268:2217-22.
38. Valentino LA, Ladisch S. Tumor gangliosides enhance alpha2beta1 integrin-dependent platelet activation. Biochim Biophys Acta 1996;1316:19-28.
39. 1A of migration capability, adhesion to vitronectin and metastatic potential of highly metastatic FBJ-LL cells. Int J Cancer 1999;83:685-91.
40. Wang X, Sun P, Al-Qamari A, Tai T, Kawashima I, Paller AS. Carbohydrate-carbohydrate binding of ganglioside to integrin α5 modulates α5β1 function. J Biol Chem 2001;276:8436-44.
41. Kazui A, Ono M, Handa K, Hakomori S. Glycosylation affects translocation of integrin, Src, and caveolin into or out of GEM. Biochem Biophys Res Commun 2000;273:159-63.
42. 1 results in the dispersion of platelet-derived growth factor receptor from glycolipid-enriched microdomains and in the suppression of cell growth signals. J Biol Chem 2000;277:11239-46.
43. Brown DA, London E. Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol 1998;14:111-36.
44. Harder T, Simons K. Caveolae, DIGs, and the dynamics of sphingolipid-cholesterol microdomains. Curr Opin Cell Biol 1997;9:534-42.