3-Methylcholanthrene inhibits lymphocyte proliferation and increases intracellular calcium levels in common carp (Cyprinus carpio L)

Aquatic Toxicology

Volumn 63, Issue 3, 2003, Pages 319-331

  Reynaud, S ^a   Duchiron, C ^a   Deschaux, P ^a  

^a Laboratory of General and Comparative Immunophysiology   (France)

Author keywords

3 Methylcholanthrene; Calcium; Lymphocytes; Proliferation

Indexed keywords

3 METHYLCHOLANTHRENE; ADENOSINE TRIPHOSPHATASE (CALCIUM); ALPHA NAPHTHOFLAVONE; CALCIUM; CONCANAVALIN A; CYTOCHROME P450 1A; ENZYME INHIBITOR; LIPOPOLYSACCHARIDE; RECEPTOR BLOCKING AGENT; THAPSIGARGIN;

PAH; POLLUTION EFFECT;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CARP; CELL ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENDOPLASMIC RETICULUM; LEUKOCYTE; LYMPHOCYTE PROLIFERATION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CALCIUM SIGNALING; CARPS; CELL DIVISION; CYTOPLASM; ENDOPLASMIC RETICULUM; INTRACELLULAR FLUID; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; METHYLCHOLANTHRENE;

CYPRINUS CARPIO;

EID: 0037426588     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-445X(02)00188-1     Document Type: Article

References (39)

1. Archuleta M.M., Shieven G.L., Ledbetter J.A., Deanin G.G., Burchiel S.W. 7,12-Dimethylbenz[a]anthracene activates protein-tyrosine kinases Fyn and Lck in the HPB-ALL human T-cell line and increases tyrosine phosphorylation of phospholipase C-γ1, formation of inositol 1,4,5-triphosphate, and mobilization of intracellular calcium. Proc. Natl. Acad. Sci. USA. 90:1993;6105-6109.
2. Arkoosh M.R., Clemons E., Myers M., Casillas E. Suppression of B-cell mediated immunity in juvenile chinook salmon (Oncorhynchus Tsawytscha) after exposure to either a polycyclic aromatic hydrocarbon or to polychlorinated biphenyl. Immunopharmacol. Immunotoxicol. 16:(2):1994;293-314.
3. Bolard J., Henry-Toulmé N. Polyclonal activators. Roitt I.M., Delves P.J. Encyclopedia of Immunology. III:1992;1250-1252 San Diego, USA.
4. Boyum A. Isolation of human blood monocytes with Nicodenz, a new non-ionic iodinated gradient medium. Scand. J. Immunol. 17:1983;429-436.
5. Burchiel S.W., Thompson T.A., Davis D.A.P. Alteration in mitogen-induced calcium mobilization and intracellular free calcium produced by 7,12-dimethylbenz(a) anthracene in the Jurkat human T cell line. Int. J. Immunopharmacol. 13:1991;109-115.
6. Carlson E.A., Li Y., Zelikoff J.T. Exposure of Japanese medaka (Oryzias latipes) to benzo[a]pyrene suppresses immune function and host resistance against bacterial challenge. Aqua. Toxicol. 56:2002;289-301.
7. Chakraborti P., Mukherjee D. Effects of prolactin and fish pituitary extract on plasma calcium levels in common carp, Cyprinus carpio. Gen. Comp. Endocrinol. 97:1995;320-326.
8. 2+-associated signaling pathways in the immunotoxicity of polycyclic aromatic hydrocarbons. J. Toxicol. Environ. Health. 45:1995;101-126.
9. Davila D.R., Romero D.L., Burchiel S.W. Human T cells are highly sensitive to supression of mitogens by polycyclic aromatic hydrocarbons and this effect is differentially reversed by α-naphtoflavone. Toxicol. Appl. Pharmacol. 139:1996;333-341.
10. Evans D.L., Harris D.T., Jaso-Friedmann L. Function associated molecules in non-specific cytotoxic cells: role in calcium signaling, redirected lysis and modulation of toxicity. Dev. Comp. Immunol. 16:1992;383-394.
11. Ferrière F., Khan N.A., Meyniel J.P., Deschaux P. Serotonin-induced calcium-channel gatting in rainbow trout (Oncorhynchus mykiss) peripheral blood lymphocytes. Biochem. J. 323:1997;251-258.
12. 2+ indicators with improved fluorescence properties. J. Biol. Chem. 260:1985;3440-3450.
13. Holsapple M.P., Snyder N.K., Wood S.T., Morris D.L. A review of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced changes in immunocompetence: 1991 update. Toxicology. 69:1991;219-255.
14. House R.V., Dean J.H. Studies on structural requirements for suppression of cytotoxic T lymphocyte induction by polycyclic compounds. In Vitro Toxicol. 1:1987;149-162.
15. Hwang P.P., Tung C.C., Chang M.H. Effect of environmental calcium levels on calcium uptake in tilapia larvae (Oreochromis mossanbicus). Fish Physiol Biochem. 15:1996;363-370.
16. Karras J.G., Morris D.L., Matulka R.A., Kramer C.M., Holsapple M.P. 2,3,78-tetrachlorodibenzo-p-dioxin (TCDD) elevates basal B-cell intracellular calcium concentration and suppresses surface Ig- but not CD40-induced antibody secretion. Toxicol. Appl. Pharmacol. 137:1996;275-284.
17. Kawabata T., White K.L. Suppression of the in vitro humoral immune response of mouse splenocytes by benzo[a]pyrene metabolites and inhibition of benzo[a]pyrene-induced immunosupression by α-naphtoflavone. Cancer Res. 47:1987;2317-2322.
18. Krieger J.A., Born J.L., Burchiel S.W. Persistence of calcium elevation in the HPB-ALL human T cell line correlates with immunosuppressive properties of polycyclic aromatic hydrocarbons. Toxicol. Appl. Pharmacol. 127:1994;268-274.
19. Krieger J.A., Davila D.R., Lytton J., Born J.L., Burchiel S.W. Inhibition of sarcoplasmic/endoplasmic reticulum calcium ATPases (SERCA) by polycyclic aromatic hydrocarbons in HPB-ALL human T cells and other tissues. Toxicol. Appl. Pharmacol. 133:1995;102-108.
20. Ladics G.S., Kawabata T.T., White K.L. Suppression of the in vitro humoral immune response of mouse splenocytes by 7,12-dimethylbenz[a]anthracene metabolites and inhibition of immunosuppression by α-naphtoflavone. Toxicol. Appl. Pharmacol. 110:1991;31-44.
21. Mounho B.J., Burchiel S.W. Alteration in human B cell calcium homeostasis by polycyclic aromatic hydrocarbons: possible association with cytochrome P450 metabolism and increased protein tyrosine phosphorylation. Toxicol. Appl. Pharmacol. 149:1998;80-89.
22. Mundzinski S.P. Effects of benzo[a]pyrene on concanavalin A-stimulated human peripheral blood mononuclear cells in vitro: inhibition of proliferation but no effect on parameters related to the G1 phase of the cell cycle. Toxicol. Appl. Pharmacol. 199:1993;166-174.
23. Putney J.W. Capacitative calcium entry revised. Cell Calcium. 11:1990;611-624.
24. Reynaud S., Duchiron C., Deschaux P. 3-methylcholanthrene increases phorbol 12-myristate 13-acetate-induced respiratory burst and intracellular calcium levels in common carp (Cyprinus carpio L) macrophages. Toxicol. Appl. Pharmacol. 175:2001;1-9.
25. Smialowicz R.J., De Vito M.J., Riddle M.M., Williams W.C., Birnbaum L.S. Opposite effects of 2,2′,4,4′,5,5′-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antibody response to sheep erythrocytes in mice. Fundam. Appl. Toxicol. 37:1997;141-149.
26. Smith D.A., Schurig G.G., Smith S.A., Holladay S.D. The hemolytic plaque-forming cell assay in tilapia (Oreochromis niloticus) exposed to benzo[a]pyrene: enhanced or depressed plaque formation depends on dosing schedule. Toxicol. Methods. 9:1999;57-70.
27. 3H]-methylcholanthrene in the perfused rat liver. Cancer Res. 37:1977;369-375.
28. 2+ in the MCF-10A human mammary epithelial cell line by carcinogenic polycyclic aromatic hydrocarbons. Mol. Carcinog. 25:(1):1999;48-54.
29. 2+-ATPase. Proc. Natl. Acad. Sci. USA. 87:1990;2466-2470.
30. Thurmond L.M., Lauer L.D., House R.V., Cook J.C., Dean J.H. Immunosuppression following exposure to 7, 12-dimethylbenz[a]anthracene (DMBA) in Ah-responsive and Ah-nonresponsive mice. Toxicol. Appl. Pharmacol. 91:1987;450-460.
31. Thurmond L.M., House R.V., Lauer L.D., Dean J.H. Suppression of splenic lymphocyte function by 7, 12-dimethylbenz[a]anthracene (DMBA) in vitro. Toxicol. Appl. Pharmacol. 93:1988;369-377.
32. Tierney B., Hewer A., Rattle H., Sims P. The formation of dihydrodiols by chemical or enzymatic oxidation of 3-methylcholanthrene. Chem. Biol. Interact. 23:1978;121-135.
33. Troutaud D., Le Morvan C., Deschaux P. A serum reduced culture medium for carp lymphocytes in vitro mitogen-induced proliferation. Fish Shellfish Immunol. 5:1995;81-84.
34. 2+ signals during early lymphocyte activation in carp Cyprinus carpio L. J. Exp. Biol. 201:1998;591-598.
35. White K.L. Jr. An overview of immunotoxicology and carcinogenic polycyclic aromatic hydrocarbons. Environ. Carcinogen. Rev. C4:1986;163-202.
36. White K.L., Lysy H.H., Holsapple M.P. Immunosuppression by polycyclic aromatic hydrocarbons: a structure activity relationship in B6C3F1 and DBA/2 mice. Immunopharmacology. 9:1985;155-164.
37. Wood S.C., Holsapple M.P. Effects of 7,12-dimethylbenz[a]anthracene on the superantigen toxic shock syndrome toxin (TSST-1)-induced proliferation and antibody secretion by human lymphocytes. Fundam. Appl. Toxicol. 20:1993;280-287.
38. Zedeck M.S. Polycyclic aromatic hydrocarbons. A review. J. Environ. Pathol. Toxicol. 3:1980;537-567.
39. Zhao M., Lytton J., Burchiel S.W. Inhibition of sarco-endoplasmic reticulum calcium ATPases (SERCA) by polycyclic aromatic hydrocarbons: lack of evidence for direct effects on cloned rat enzymes. Int. J. Immunopharmacol. 18:1996;589-598.