Inhibition of sarco-endoplasmic reticulum calcium ATPases (SERCA) by polycyclic aromatic hydrocarbons: Lack of evidence for direct effects on cloned rat enzymes

International Journal of Immunopharmacology

Volumn 18, Issue 10, 1996, Pages 589-598

  Zhao, Meifen ^a   Lytton, Jonathan ^b   Burchiel, Scott W ^a  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b Health Sciences Centre Calgary   (Canada)

Author keywords

Ca2+ ATPase; Calcium signaling; Polycyclic aromatic hydrocarbons (PAHs); SERCA

Indexed keywords

2,5 DI TERT BUTYLHYDROQUINONE; 3 METHYLCHOLANTHRENE; 7,12 DIMETHYLBENZ[A]ANTHRACENE; ADENOSINE TRIPHOSPHATASE (CALCIUM); ANTHRACENE; BENZ[A]ANTHRACENE; BENZO[A]PYRENE; BENZO[E]PYRENE; POLYCYCLIC AROMATIC HYDROCARBON; THAPSIGARGIN;

ARTICLE; CALCIUM HOMEOSTASIS; COLORIMETRY; ENDOPLASMIC RETICULUM; ENZYME INHIBITION; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; MOLECULAR CLONING; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM-TRANSPORTING ATPASES; CLONING, MOLECULAR; COLORIMETRY; DNA, COMPLEMENTARY; ENDOPLASMIC RETICULUM; HUMANS; HYDROLYSIS; ISOENZYMES; POLYCYCLIC HYDROCARBONS, AROMATIC; RATS; SARCOPLASMIC RETICULUM; SPECTROPHOTOMETRY; T-LYMPHOCYTES;

EID: 0030268314     PISSN: 01920561     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0192-0561(96)00063-X     Document Type: Article

References (29)

1. Archuleta, M. M., Schieven, G. L., Ledbetter, J. A., Deanin, G. G. & Burchiel, S. W. (1993) DMBA activates protein-tyrosine kinases Fyn and Lck in the HPB-ALL human T cell line and increases tyrosine phosphorylation of intracelluar calcium. Proc. natn. Acad. Sci. U.S.A., 90, 6105-6109.
2. 2+ produced by 7,12-dimethylbenz(a)anthracene (DMBA) in the Jurkat human T cell line. Int. J. Immunopharmacol., 13, 109-115.
3. 2+ and DNA damage. Toxicol. Appl. Pharmacol., 113, 126-132.
4. Burchiel, S. W., Davis, D. P., Ray, S. D. & Barton, S. L. (1993) DMBA induces programmed cell death (apotosis) in the A20.1 murine B cell lymphoma. Fund. Appl. Toxicol., 21, 120-124.
5. 2+-stimulated ATPase activity. Analyt. Biochem., 157, 375-380.
6. Conney, A. H. (1982) Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture. Cancer Res., 42, 4875-4917.
7. 2+-associated signaling pathways in the immunotoxicity of polycyclic aromatic hydrocarbons. J. Toxicol. Environ. Health, 44, 101-126.
8. Davila, D. R., Romero, D. L. & Burchiel, S. W. (1996) Human T cells are highly sensitive to suppression of mitogenesis by polycyclic aromatic hydrocarbons and this effect is differentially reversed by α-napthoflavone. Toxicol. Appl. Pharmacol., 139, 333-341.
9. 2+-dependent pathways of B-cell activation by DMBA. Toxicol. Appl. Pharmacol., 116, 202-208.
10. Dipple, A. (1976) Polynuclear aromatic carcinogens. In Chemical Carcinogenesis, Am. Chem. Soc. monograph 173 (ed. Searle, C. E.), pp. 245-314. American Chemical Society, Washington, DC..
11. Gardner, P. (1989) Calcium and T lymphocyte activation. Cell, 59, 15-20.
12. Gelboin, H. V. (1980) Benzo[a]pyrene metabolism, activation, and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes. Physiol. Rev., 60, 1107-1166.
13. Graham, F. L. & Smiley, J. (1977) Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol., 36, 59-72.
14. Holsapple, M. P., Karras, J. G., Ledbetter, J. A., Schieven, G. L., Burchiel, S. W., Davila, D. R., Schatz, A. R. & Kaminski, N. E. (1996) Molecular mechanisms of toxicant-induced immunosuppression: role of second messengers. Ann. Rev. Pharmacol. Toxicol., 36, 131-139.
15. 2+ pool. J. Biol. Chem., 264, 15192-15198.
16. Kaufman, R. J., Davies, M. V., Pathak, V. K. & Hershey, J. W. B. (1989) The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs. Molec. Cell. Biol., 9, 946-958.
17. Krieger, J. A., Born, J. L. & Burchiel, S. W. (1994) Persistence of calcium elevation in the HPB-ALL human T cell line correlates with immunosuppressive properties of polycyclic aromatic hydrocarbons. Toxicol. Appl. Pharmacol., 127, 268-274.
18. Krieger, J. A., Davila, D. R., Lytton, J. L., Born, J. L. & Burchiel, S. W. (1995) Inhibition of sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) by polycyclic aromatic hydrocarbons in HPB-ALL human T cells and other tissues. Toxicol. Appl. Pharmacol., 133, 102-108.
19. 2+ pumps. J. Biol. Chem., 266, 17067-17071.
20. 2+ pumps. J. Biol. Chem., 267, 14483-14489.
21. 2+-ATPase expressed in COS-1 cells. Proc. Natn. Acad. Sci. U.S.A., 85, 3314-3318.
22. 2+-sequestration. FEBS Lett., 224, 331-336.
23. Mudzinski, S. P. (1993) Effects of benzo(a)pyrene on concanavalin A-stimulated human peripheral blood mononuclear cells in vitro: inhibition of proliferation but no effects on parameters related to the G1 phase of the cell cycle. Toxicol. Appl. Pharmacol., 119, 166-174.
24. Okano, P., Miller, H. N., Robinson, R. C. & Gleboin, H. V. (1979) Comparison of benzo(a)pyrene and (-)-trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene metabolism in human blood monocytes and lymphocytes. Cancer Res., 39, 3184-3193.
25. Seals, J. R., McDonald, J. M., Bruns, D. & Jarett, L. (1978) A sensitive and precise isotopic assay of ATPase activity. Analyt. Biochem., 90, 785-795.
26. Thastrup, O., Dawson, A. P., Scharff, O., Foder, B., Cullen, P. J., Drobak, B. K., Bjerrum, S. B., Christensen, S. B. & Handley, M. R. (1989) Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage. Agents Actions, 27, 17-23.
27. 2+-ATPase transcripts. Am. J. Physiol., 269, C775-C784.
28. 2+ pump is expressed in platelets, in lymphoid cells, and in mast cells. J. Biol. Chem., 269, 1410-1416.
29. Zedeck, M. S. (1980) Polycyclic aromatic hydrocarbons, a review. J. Environ. Pathol. Toxicol., 3, 537-567.