Reductions in N-acetylaspartylglutamate and the 67 kDa form of glutamic acid decarboxylase immunoreactivities in the visual system of albino and pigmented rats after optic nerve transections

Journal of Comparative Neurology

Volumn 458, Issue 3, 2003, Pages 221-239

  Moffett, John R ^a,b  

^a GEORGETOWN UNIVERSITY   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

GABA; Glutamic acid decarboxylase; Immunohistochemistry; Lateral geniculate; NAAG

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; N ACETYLASPARTYLGLUTAMIC ACID;

ANIMAL TISSUE; ARTICLE; CELL POPULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LATERAL GENICULATE BODY; MALE; NERVE PROJECTION; NERVE TRANSECTION; NEUROTRANSMISSION; NONHUMAN; OPTIC CHIASM; OPTIC NERVE; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; SUPRACHIASMATIC NUCLEUS; SYNAPSE; THALAMUS NUCLEUS; VISUAL SYSTEM;

ANIMALS; BRAIN; DIPEPTIDES; DOWN-REGULATION; FUNCTIONAL LATERALITY; GAMMA-AMINOBUTYRIC ACID; GENICULATE BODIES; GLUTAMATE DECARBOXYLASE; IMMUNOHISTOCHEMISTRY; INTERNEURONS; ISOENZYMES; MALE; NEURAL INHIBITION; OPTIC NERVE; PRESYNAPTIC TERMINALS; RATS; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; RETINAL GANGLION CELLS; SUPERIOR COLLICULUS; VISUAL PATHWAYS;

EID: 0037424674     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/cne.10570     Document Type: Article

References (65)

1. Anderson KJ, Borja MA, Cotman CW, Moffett JR, Namboodiri MA, Neale JH. 1987. N-acetylaspartylglutamate identified in the rat retinal ganglion cells and their projections in the brain. Brain Res 411:172-177.
2. Berg EA, Johnson RJ, Leeman SE, Boyd N, Kimerer L, Fine RE. 2000. Isolation and characterization of substance P-containing dense core vesicles from rabbit optic nerve and termini. J Neurosci Res 62:830-839.
3. Bos NPA, Mirmiran M. 1993. Effects of excitatory and inhibitory amino acids on neuronal discharges in the cultured suprachiasmatic nucleus. Brain Res Bull 31:67-72.
4. Bruno V, Wroblewska B, Wroblewski JT, Fiore L, Nicoletti F. 1998a. Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells. Neuroscience 85:751-757.
5. Bruno V, Battaglia G, Casabona G, Copani A, Caciagli F, Nicoletti F. 1998b. Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta. J Neurosci 18:9594-9600.
6. Cardozo BN, Buijs R, Van der Want J. 1991. Glutamate-like immunoreactivity in retinal terminals in the nucleus of the optic tract in rabbits. J Comp Neurol 309:261-270.
7. Crunelli V, Kelly JS, Leresche N, Pirchio M. 1987. On the excitatory post-synaptic potential evoked by stimulation of the optic tract in the rat lateral geniculate nucleus. J Physiol (London) 384:603-618.
8. Funke K, Eysel UT, FitzGibbon T. 1991. Retinogeniculate transmission by NMDA and non-NMDA receptors in the cat. Brain Res 547;229-238.
9. Galli T, Godeheu G, Artaud F, Desce JM, Pittaluga A, Barbeito L, Glowinski J, Chëramy A. 1991. Specific role of N-acetyl-aspartyl-glutamate in the in vivo regulation of dopamine release from dendrites and nerve terminals of nigrostriatal dopaminergic neurons in the cat. Neuroscience 42:19-28.
10. Ghose S, Wroblewska B, Corsi L, Grayson DR, de Blas AL, Vicini S, Neale JH. 1997. N-acetylaspartylglutamate stimulates metabotropic glutamate receptor 3 to regulate expression of the GABA(A) alpha6 subunit in cerebellar granule cells. J Neurochem 69:2326-2335.
11. Gonzalo-Ruiz A, Sanz JM, Lieberman AR. 1996. Immunohistochemical studies of localization and colocalization of glutamate, aspartate, and GABA in the anterior thalamic nuclei, retrosplenial granular cortex, thalamic reticular nucleus, and mammillary nuclei of the rat. J Chem Neuroanat 12:77-84.
12. Haak LL, Heller HC, Van den Pol AN. 1997. Metabotropic glutamate receptor activation modulates kainate and serotonin calcium response in astrocytes. J Neurosci 17:1825-1837.
13. Henderson Z, Salt TE. 1988. The effects of N-acetylaspartylglutamate and distribution of N-acetylaspartylglutamate-like immunoreactivity in the rat somatosensory thalamus. Neuroscience 25:899-906.
14. Johnson RF, Morin LP, Moore RY. 1988. Retinohypothalamic projections in the hamster and rat demonstrated using cholera toxin. Brain Res 462:301-312.
15. Jones HE, Sillito AM. 1992. The action of the putative neurotransmitters N-acetylaspartylglutamate and L-homocysteate in cat dorsal lateral geniculate nucleus. J Neurophysiol 68:663-672.
16. Kemp JA, Sillito AM. 1982. The nature of the excitatory transmitter mediating X and Y cell inputs to the cat dorsal lateral geniculate nucleus. J Physiol (London) 323:377-391.
17. Kita H, Oomura Y. 1982. An anterograde HRP study of retinal projections to the hypothalamus in the rat. Brain Res Bull 8:249-253.
18. Lea PM, Wroblewska B, Sarvey JM, Neale JH. 2001. Beta-NAAG rescues LTP from blockade by NAAG in rat dentate gyrus via the type 3 metabotropic glutamate receptor. J Neurophysiol 85:1097-1106.
19. Lu XM, Tang Z, Liu W, Lin Q, Slusher BS. 2000. N-acetylaspartylglutamate protects against transient focal cerebral ischemia in rats. Eur J Pharmacol 408:233-239.
20. Moffett JR, Namboodiri MA. 1995. Differential distribution of N-acetylaspartylglutamate and N-acetylaspartate immunoreactivities in rat forebrain. J Neurocytol 24:409-433.
21. Moffett JR, Williamson LC, Palkovits M, Namboodiri MA. 1990. N-acetylaspartylglutamate: a transmitter candidate for the retinohypothalamic tract. Proc Natl Acad Sci USA 87:8065-8069.
22. Moffett JR, Namboodiri MA, Cangro CB, Neale JH. 1991a. Immunohistochemical localization of N-acetylaspartate in rat brain. Neuroreport 2:131-134.
23. Moffett JR, Williamson LC, Neale JH, Palkovits M, Namboodiri MA. 1991b. Effect of optic nerve transection on N-acetylaspartylglutamate immunoreactivity in the primary and accessory optic projection systems in the rat. Brain Res 538:86-94.
24. Moffett JR, Namboodiri MA, Neale JH. 1993. Enhanced carbodiimide fixation for immunohistochemistry: application to the comparative distributions of N-acetylaspartylglutamate and N-acetylaspartate immunoreactivities in rat brain. J Histochem Cytochem 41:559-570.
25. 67 immunoreactivities in the cerebellum and precerebellar nuclei of the rat utilizing enhanced carbodiimide fixation and immunohistochemistry. J Comp Neurol 347:598-618.
26. Molinar-Rode R, Pasik P. 1992. Amino acids and N-acetyl-aspartylglutamate as neurotransmitter candidates in the monkey retinogeniculate pathways. Exp Brain Res 89:40-48.
27. Montero VM. 1990. Quantitative immunogold analysis reveals high glutamate levels in synaptic terminals of retino-geniculate, cortico-geniculate, and geniculo-cortical axons in the cat. Vis Neurosci 4:437-443.
28. Montero VM, Wenthold RJ. 1989. Quantitative immunogold analysis reveals high glutamate levels in retinal and cortical synaptic terminals in the lateral geniculate nucleus of the macaque. Neuroscience 31:639-647.
29. Moore RY, Speh JC. 1993. GABA is the principal neurotransmitter of the circadian system. Neurosci Lett 150:112-116.
30. Neale JH, Bzdega T, Wroblewska B. 2000. N-acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system. J Neurochem 75:443-452.
31. 3H]norepinephrine release from rat hippocampal slices. J Pharmacol Exp Ther 266:796-803.
32. Radhakrishnan V, Henry JL. 1993. Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord. Neuroscience 55:531-544.
33. Reese BE. 1988. 'Hidden lamination' in the dorsal lateral geniculate nucleus: the functional organization of this thalamic region in the rat. Brain Res 472:119-137.
34. Rimvall K, Martin DL. 1992. Increased intracellular gamma-aminobutyric acid selectively lowers the level of the larger of two glutamate decarboxylase proteins in cultured GABAergic neurons from rat cerebral cortex. J Neurochem 58:158-166.
35. 67 protein is highly sensitive to small increases in intraneuronal gamma-aminobutyric acid levels. J Neurochem 62:1375-1381.
36. 67 protein and mRNA levels in rat cerebral cortex. J Neurochem 60:714-720.
37. Riveros N, Orrego F. 1984. A study of possible excitatory effects of N-acetylaspartylglutamate in different in vivo and in vitro brain preparations. Brain Res 299:393-395.
38. Schweitzer C, Kratzeisen C, Adam G, Lundstrom K, Malherbe P, Ohresser S, Stadler H, Wichmann J, Woltering T, Mutel V. 2000. Characterization of [(3)H]-LY354740 binding to rat mGlu2 and mGlu3 receptors expressed in CHO cells using semliki forest virus vectors. Neuropharmacology 39:1700-1706.
39. Sekiguchi M, Wada K, Wenthold RJ. 1992. N-acetylaspartylglutamate acts as an agonist upon homomeric NMDA receptor (NMDAR1) expressed in Xenopus oocytes. FEBS Lett 311:285-289.
40. Serval V, Barbeito L, Pittaluga A, Cheramy A, Lavielle S, Glowinski J. 1990. Competitive inhibition of N-acetylated-alpha-linked acidic dipeptidase activity by N-acetyl-L-aspartyl-beta-linked L-glutamate. J Neurochem 55:39-46.
41. Sillito AM, Murphy PC, Salt TE. 1990a. The contribution of the non-N-methyl-D-aspartate group of excitatory amino acid receptors to retinogeniculate transmission in the cat. Neuroscience 34:273-280.
42. Sillito AM, Murphy PC, Salt TE, Moody CI. 1990b. Dependence of retino-geniculate transmission in cat on NMDA receptors. J Neurophysiol 63:347-355.
43. Swanson LW. 1992. Brain maps: structure of the rat brain. Amsterdam: Elsevier.
44. Thomas AG, Vornov JJ, Olkowski JL, Merion AT, Slusher BS. 2000. N-acetylated alpha-linked acidic dipeptidase converts N- acetylaspartylglutamate from a neuroprotectant to a neurotoxin. J Pharmacol Exp Ther 295:16-22.
45. Tieman SB, Tieman DG. 1996. N -acetylaspartylglutamate immunoreactivity in human retina. Vis Res 36:941-947.
46. Tieman SB, Cangro CB, Neale JH. 1987. N-acetylaspartylglutamate immunoreactivity in neurons of the cat's visual system. Brain Res 420:188-193.
47. Tieman SB, Butler K, Neale JH. 1988. N-acetylaspartylglutamate. A neuropeptide in the human visual system. JAMA 259:2020.
48. Tieman SB, Neale JH, Tieman DG. 1991a. N-acetylaspartylglutamate immunoreactivity in neurons of the monkey's visual pathway. J Comp Neurol 313:45-64.
49. Tieman SB, Moffett JR, Irtenkauf SM. 1991b. Effect of eye removal on N-acetylaspartylglutamate immunoreactivity in retinal targets of the cat. Brain Res 562:318-322.
50. Trombley PQ, Westbrook GL. 1990. Excitatory synaptic transmission in cultures of rat olfactory bulb. J Neurophysiol 64:598-606.
51. 3H]acetylaspartylglutamate from the optic pathway. J Neurochem 51:1956-1959.
52. Valivullah HM, Lancaster J, Sweetnam PM, Neale JH. 1994. Interactions between N-acetylaspartylglutamate and AMPA, kianate and NMDA binding sites. J Neurochem 63:1714-1719.
53. Van den Pol AN. 1991. Glutamate and aspartate immunoreactivity in hypothalamic presynaptic axons. J Neurosci 11:2087-2101.
54. Westbrook GL, Mayer ML, Namboodiri MA, Neale JH. 1986. High concentrations of N-acetylaspartylglutamate (NAAG) selectively activate NMDA receptors on mouse spinal cord neurons in cell culture. J Neurosci 6:3385-3392.
55. Whittemore ER, Koerner JF. 1989. An explanation for the purported excitation of piriform cortical neurons by N-acetyl-L-aspartyl-L-glutamic acid (NAAG). Proc Natl Acad Sci USA 86:9602-9605.
56. Williamson LC, Neale JH. 1988. Calcium-dependent release of N-acetylaspartylglutamate from retinal neurons upon depolarization. Brain Res 475:151-155.
57. Williamson LC, Eagles DA, Brady MJ, Moffett JR, Namboodiri MA, Neale JH. 1991. Localization and synaptic release of N-acetylaspartylglutamate in the chick retina and optic tectum. Eur J Neurosci 3:441-451.
58. Wroblewska B, Wroblewski JT, Saab OH, Neale JH. 1993. N-acetylaspartylglutamate inhibits forskolin-stimulated cyclic AMP levels via a metabotropic glutamate receptor in cultured cerebellar granule cells. J Neurochem 61:943-948.
59. Wroblewska B, Wroblewski JT, Pshenichkin S, Surin A, Sullivan SE, Neale JH. 1997. N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells. J Neurochem 69:174-181.
60. Wroblewska B, Santi MR, Neale JH. 1998. N- acetylaspartylglutamate activates cyclic AMP-coupled metabotropic glutamate receptors in cerebellar astrocytes. Glia 24:172-179.
61. Xi ZX, Baker DA, Shen H, Carson DS, Kalivas PW. 2002. Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens. J Pharmacol Exp Ther 300:162-171.
62. Xing LC, Tieman SB. 1993. Relay cells, not interneurons, of cat's lateral geniculate nucleus contain N-acetylaspartylglutamate. J Comp Neurol 330:272-285.
63. Yamamoto T, Nozaki-Taguchi N, Sakashita Y. 2001. Spinal N-acetyl-alpha-linked acidic dipeptidase (NAALADase) inhibition attenuates mechanical allodynia induced by paw carrageenan injection in the rat. Brain Res 909:138-144.
64. Zhao J, Ramadan E, Cappiello M, Wroblewska B, Bzdega T, Neale JH. 2001. NAAG inhibits KCl-induced [(3)H]-GABA release via mGluR3, cAMP, PKA and L-type calcium conductance. Eur J Neurosci 13:340-346.
65. Zollinger M, Amsler U, Do KQ, Streit P, Cuenod M. 1988. Release of N-acetylaspartylglutamate on depolarization of rat brain slices. J Neurochem 51:1919-1923.