Gene transfer of extracellular superoxide dismutase reduces arterial pressure in spontaneously hypertensive rats: Role of heparin-binding domain

Circulation Research

Volumn 92, Issue 4, 2003, Pages 461-468

  Chu, Yi ^a   Iida, Shinichiro ^a   Lund, Donald D ^a,b   Weiss, Robert M ^a,b   DiBona, Gerald F ^a,b   Watanabe, Yoshimasa ^a   Faraci, Frank M ^a   Heistad, Donald D ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Gene therapy; Hypertension; Oxidative stress; Spontaneously hypertensive rats; Superoxide

Indexed keywords

ACETYLCHOLINE; ADENOVIRUS VECTOR; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL REACTIVITY; CAROTID ARTERY; CELL ADHESION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME MECHANISM; GENE THERAPY; GENE TRANSFER; HEART OUTPUT; IMMUNOHISTOCHEMISTRY; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RAT STRAIN; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTEMIC VASCULAR RESISTANCE; VASOMOTOR REFLEX; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANESTHESIA; ANIMALS; BINDING SITES; BLOOD PRESSURE; CARDIAC OUTPUT; CONSCIOUSNESS; GENE THERAPY; GENETIC VECTORS; HEPARIN; HUMANS; HYPERTENSION; INJECTIONS, INTRAVENOUS; MALE; MUTATION; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SUPEROXIDE DISMUTASE; TIME FACTORS;

EID: 0037423865     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000057755.02845.F9     Document Type: Article

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