Kinetic mechanism and catalysis of a native-state prolyl isomerization reaction

Journal of Molecular Biology

Volumn 326, Issue 1, 2003, Pages 235-246

  Pappenberger, Günter ^a,d   Bachmann, Annett ^a   Müller, Rita ^a   Aygün, Hüseyin ^b,c   Engels, Joachim W ^b   Kiefhaber, Thomas ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b Inst Organische Chem/C   (Germany)

^c BioSpring GmbH   (Germany)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Cyclophilin; Native state heterogeneity; Prolyl cis trans isomerization; Protein folding kinetics; Tendamistat

Indexed keywords

CYCLOPHILIN; ISOMERASE; PEPTIDE; PROLINE DERIVATIVE; PROLYL ISOMERASE; TENDAMISTAT; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; CATALYSIS; CHEMICAL REACTION KINETICS; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ISOMERISM; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE; SPECTROSCOPY;

EID: 0037423711     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)01373-6     Document Type: Article

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