A general method for the asymmetric synthesis of both enantiomers of 1-substituted 1,2,3,4-tetrahydro-β-carbolines employing pyroglutamic acid derivatives as chiral auxiliaries

Tetrahedron

Volumn 59, Issue 19, 2003, Pages 3527-3536

  Itoh, Takashi ^a   Miyazaki, Michiko ^a   Ikeda, Sachiko ^a   Nagata, Kazuhiro ^a   Yokoya, Masashi ^a   Matsuya, Yuji ^a   Enomoto, Yasuko ^a   Ohsawa, Akio ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

(S) pyroglutamic acid; Allyltributyltin; Asymmetric addition; Chiral auxiliary; Indole alkaloid; Silyl enol ether; carboline

Indexed keywords

ALLYL COMPOUND; ALLYL TRIBUTYLTIN; CARBOLINE DERIVATIVE; PYROGLUTAMIC ACID DERIVATIVE; SILANE DERIVATIVE; SILYL ETHER; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHIRALITY; CYCLOADDITION; DIASTEREOISOMER; ENANTIOMER; HYDROLYSIS; ISOMER; PRIORITY JOURNAL; STEREOCHEMISTRY; SYNTHESIS; TECHNIQUE;

EID: 0037420873     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(03)00420-4     Document Type: Article

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