Synthesis of 2,4-disubstituted quinolines by reactions of o-isocyano-β-methoxystyrene derivatives with organolithiums

Chemistry Letters

Volumn 32, Issue 1, 2003, Pages 76-77

  Kobayashi, Kazuhiro ^a   Yoneda, Keiichi ^a   Mano, Masaaki ^a   Morikawa, Osamu ^a   Konishi, Hisatoshi ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 ISOCYANO BETA METHOXYSTYRENE; KETONE DERIVATIVE; ORGANOLITHIUM COMPOUND; QUINOLINE DERIVATIVE; STYRENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

EID: 0037419576     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.2003.76     Document Type: Article

References (38)

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11. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
12. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
13. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
14. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
15. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
16. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
17. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
18. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
19. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
20. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
21. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
22. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
23. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
24. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
25. For recent excellent reviews: G. Jones, in "Comprehensive Heterocyclic Chemistry II," ed. by A, R. Katritzky, C. W. Rees, E. F. V. Scriven, Pergamon, Oxford (1996), Vol. 5, p 167; J. E. Toomey and R. Murigan, in "Progress in Heterocyclic Chemistry," ed. by H. Suschitzky and G. W. Gribble, Elsevier, Oxford (1996), Vol. 8, p 214; D. L. Commins and S. O'Connor, in "Progress in Heterocyclic Chemistry," ed. by G. W. Gribble and T. L. Gilchrist, Elsevier, Oxford (1997), Vol. 9, p 231; For recent reports: S. Cacchi, G. Fabrizi, and F. Marinelli, Synlett, 1999, 401; C. S. Cho, B. H. Oh, and S. C. Shim, J. Heterocycl. Chem., 36, 1175 (1999); M. Tokunaga, M. Eckert, and Y. Wakatsuki, Angew. Chem., Int. Ed. Engl., 38, 3222 (1999); A. Arcadi, F. Marinelli, and E. Rossi, Tetrahedron, 55, 13233 (1999); B. C. Ranu, A. Hajra, and U. Jana, Tetrahedron Lett., 41, 531 (2000); C. S. Cho, B. Y. Oh, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2000, 1885; C. S. Cho, J. S. Kim, B. H. Oh, T.-J. Kim, S. C. Shim, and N. S. Yoon, Tetrahedron, 56, 7747 (2000); H. Tokuyama, M. Sato, T. Ueda, and T. Fukuyama, Heterocycles, 54, 105 (2001); H. Amii, Y. Kishikawa, and K. Uneyama, Org. Lett., 3, 1109 (2001); M. Karikomi, H. Tsukuda, and T. Toda, Heterocycles, 55, 1249 (2001); N. J. Tom and E. M. Ruel, Synthesis, 2001, 1351; M. Shimizu, A. Oishi, Y. Taguchi, T. Sano, Y. Gama, and I. Shibuya, Heterocycles, 55, 1971 (2001); C. S. Cho, J. S. Kim, T.-J. Kim, and S. C. Shim, Chem. Commun., 2001, 2576; M. A. Fakhfakh, X. Frank, A. Fournet, R. Hocquemiller, and B. Figadère, Tetrahedron Lett., 42, 3847 (2001) and references cited therein.
26. The quinoline synthesis initiated by the addition of nuleophiles to the isocyanide carbon of (o-isocyanophenyl)acetylenes has been reported: M. Suginome, T. Fukuda, and Y. Ito, Org. Lett., 1, 1977 (1999).
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38. 18NCl: C, 77.15; H, 6.13; N, 4.74.